Clustering cell nuclei on microgrooves for disease diagnosis using deep learning

Abstract Various diseases including laminopathies and certain types of cancer are associated with abnormal nuclear mechanical properties that influence cellular and nuclear deformations in complex environments. Recently, microgroove substrates designed to mimic the anisotropic topography of the base...

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Bibliographic Details
Main Authors: Bettina Roellinger, Francois Thenier, Claire Leclech, Catherine Coirault, Elsa Angelini, Abdul I. Barakat
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-05788-2
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