Data-driven analyses of human antibody variable domain germlines: pairings, sequences and structural features

The Observed Antibody Space provides the most abundant collection of annotated paired antibody variable domain sequences, thus offering a unique platform for the systematic investigation of the factors governing the pairing of antibody heavy and light chains. By examining a range of characteristics,...

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Bibliographic Details
Main Authors: Clarissa A. Seidler, Vera A. Spanke, Jakob Gamper, Alexander Bujotzek, Guy Georges, Klaus R. Liedl
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:mAbs
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2025.2507950
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