Global deletion of the immune cell transcription factor, T-bet, alters gut microbiota and insulin sensitivity in mice

The gut microbiota plays a role in energy homeostasis: its composition differs in lean and obese mice and may impact insulin sensitivity. The immune system has co-evolved with the gut microbiota, but direct regulation of microbial communities by the immune system and its metabolic impact is unclear....

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Bibliographic Details
Main Authors: E. Stolarczyk, C. T. Vong, N. Garrido-Mesa, E. Marks, D. Abdel-Aziz, Q. Ju, I. Jackson, N. Powell, G. M. Lord, J. K. Howard
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Genetics
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Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1502832/full
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