Broad-spectrum antiviral activity of the sigma-1 receptor antagonist PB28 against coronaviruses

The continuous evolution of coronaviruses poses persistent and severe threats to both human and animal health. While α- and β-coronaviruses mainly infect mammals, including humans, γ-coronaviruses predominantly infect poultry, causing substantial economic losses. Their rapid mutation rates and wide...

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Bibliographic Details
Main Authors: Gaojie Song, Lingling Cheng, Xingpeng Dong, Dapeng Li, Jia Cheng, Chao Shang, Xiao Li, Ran Zhu, Cuiling Zhang, Junwei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1636035/full
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