Case Report: A rare case of MET-amplified gastric cancer with systemic metastasis: remarkable efficacy of crizotinib and the role of precision medicine

Gastric cancer remains one of the most prevalent gastrointestinal malignancies, with certain subtypes, such as poorly cohesive carcinoma—including signet ring cell carcinoma (SRCC)—exhibiting aggressive progression and poor prognosis. Mesenchymal epithelial transition (MET) amplification, a relative...

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Bibliographic Details
Main Authors: Yan Shen, Yaxin Xu, Jing Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1555801/full
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