Temporal analysis of doxorubicin-induced cardiac toxicity and hypertrophy

Abstract Doxorubicin (DOX), although effective in treating cancer, has significant cardiac side effects, which limit its clinical utility. In this study, we collected time-course transcriptomics and metabolomics data from the human cardiomyocyte cell line AC16, which we analyzed along with curated p...

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Bibliographic Details
Main Authors: Yu-Te Lin, Yi-Ju Lee, Wen-Wei Tseng, Zih-Hua Chen, Huai-Ching Hsieh, Ko-Hong Lin, Jin-Yu Su, An-Chi Wei
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-025-00545-7
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