Oxidative Stress by H<sub>2</sub>O<sub>2</sub> as a Potential Inductor in the Switch from Commensal to Pathogen in Oncogenic Bacterium <i>Fusobacterium nucleatum</i>

Oxidative Stress by H<sub>2</sub>O<sub>2</sub> as a Potential Inductor in the Switch from Commensal to Pathogen in Oncogenic Bacterium <i>Fusobacterium nucleatum</i>

Background: <i>Fusobacterium nucleatum</i> is a pathobiont that plays a dual role as both a commensal and a pathogen. The oral cavity typically harbors this anaerobic, Gram-negative bacterium. At the same time, it is closely linked to colorectal cancer due to its potential involvement in...

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Main Authors: Alessandra Scano, Sara Fais, Giuliana Ciappina, Martina Genovese, Barbara Granata, Monica Montopoli, Pierluigi Consolo, Patrizia Carroccio, Paola Muscolino, Alessandro Ottaiano, Alessia Bignucolo, Antonio Picone, Enrica Toscano, Germano Orrù, Massimiliano Berretta
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Antioxidants
Subjects:
<i>Fusobacterium nucleatum</i>
colon-rectal cancer
oxidative stress
pri-miRNA
gene expression
Online Access:https://www.mdpi.com/2076-3921/14/3/323
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