Analyzing immune cell infiltrates in skeletal muscle of infantile-onset Pompe disease using bioinformatics and machine learning

Analyzing immune cell infiltrates in skeletal muscle of infantile-onset Pompe disease using bioinformatics and machine learning

Abstract Pompe disease, a severe lysosomal storage disorder, is marked by heart problems, muscle weakness, and respiratory difficulties. This study aimed to identify novel markers for infantile-onset Pompe disease by analyzing key genes and immune cells infiltrating affected skeletal muscles, buildi...

Full description

Saved in:
Bibliographic Details
Main Authors: Jingfei Zhang, Xinyu Lin, Lan Yin, Yue Song, Xinglu Chen, Yingchuan Zhu, Wenhao Jiang, Yilu Lu, Yongxin Ma
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Pompe disease
GEO datasets
Signatures
Immune cells infiltration
Machine learning
Online Access:https://doi.org/10.1038/s41598-024-78634-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-024-78634-6

Similar Items