Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model

Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model

Correlative studies have linked human gut microbes to specific health conditions. Alistipes is one such microbial genus negatively linked to inflammatory bowel disease (IBD). However, the protective role of Alistipes in IBD is understudied, and the underlying molecular mechanisms remain unknown. In...

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Bibliographic Details
Main Authors: Ethan A. Older, Mary K. Mitchell, Andrew Campbell, Xiaoying Lian, Michael Madden, Yuzhen Wang, Lauren E. van de Wal, Thelma Zaw, Brandon N. VanderVeen, Rodney Tatum, E. Angela Murphy, Yan-Hua Chen, Daping Fan, Melissa Ellermann, Jie Li
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Alistipes
inflammation
IBD
colitis
gut microbes
sulfonolipids
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2517380
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