Predicting survival, neurotoxicity and response in B-cell lymphoma patients treated with CAR-T therapy using an imaging features-based model

Predicting survival, neurotoxicity and response in B-cell lymphoma patients treated with CAR-T therapy using an imaging features-based model

Abstract Background This multicentre retrospective observational study aims to develop imaging-based prognostic and predictive models for relapsed/refractory (R/R) B-cell lymphoma patients undergoing CAR-T therapy by integrating clinical data and imaging features. Specifically, our aim was to predic...

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Main Authors: Blanca Ferrer-Lores, Alfonso Ortiz-Algarra, Alfonso Picó-Peris, Alejandra Estepa-Fernández, Fuensanta Bellvís-Bataller, Glen J. Weiss, Almudena Fuster-Matanzo, Juan Pedro Fernández, Ana Jimenez-Pastor, Rafael Hernani, Ana Saus-Carreres, Ana Benzaquen, Laura Ventura, José Luis Piñana, Ana Belén Teruel, Alicia Serrano-Alcalá, Rosa Dosdá, Pablo Sopena-Novales, Aitana Balaguer-Rosello, Manuel Guerreiro, Jaime Sanz, Luis Martí-Bonmatí, María José Terol, Ángel Alberich-Bayarri
Format: Article
Language:English
Published: SpringerOpen 2024-11-01
Series:EJNMMI Research
Subjects:
CAR-T cells therapy
Non-Hodgkin lymphoma
Radiomics
Survival prediction
ICANS prediction
Treatment response prediction
Online Access:https://doi.org/10.1186/s13550-024-01172-9
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https://doi.org/10.1186/s13550-024-01172-9

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