Exploring genetic associations between immune cells and hypertensive disorder of pregnancy using Mendelian randomization

Exploring genetic associations between immune cells and hypertensive disorder of pregnancy using Mendelian randomization

Abstract Background Observational epidemiological studies suggested that immunological dysregulation and inflammation play a significant role in the placental and renal dysfunction that leads to maternal hypertension. The immunophenotypes' possible causalities with hypertensive disease of pregn...

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Bibliographic Details
Main Authors: Jingting Liu, Yijun Dong, Yawei Zhou, Wendi Wang, Yan Li, Jianying Pei
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Pregnancy and Childbirth
Subjects:
Hypertensive disorders of pregnancy (HDP)
Immunophenotype
Mendelian randomization
Causality
Mediation analysis
Online Access:https://doi.org/10.1186/s12884-024-06950-w
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https://doi.org/10.1186/s12884-024-06950-w

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