Angiogenesis as a Survival Mechanism in Heartworm Disease: The Role of Fructose-Bisphosphate Aldolase and Actin from <i>Dirofilaria immitis</i> in an In Vitro Endothelial Model

Angiogenesis as a Survival Mechanism in Heartworm Disease: The Role of Fructose-Bisphosphate Aldolase and Actin from <i>Dirofilaria immitis</i> in an In Vitro Endothelial Model

Heartworm disease, caused by <i>Dirofilaria immitis,</i> is a vector-borne zoonotic disease, (mainly affecting canids and felids) causing chronic vascular and pulmonary pathology in its early stages, which worsens with parasite load and/or death of adult worms in the pulmonary artery or...

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Bibliographic Details
Main Authors: Manuel Collado-Cuadrado, Claudia Alarcón-Torrecillas, Alfonso Balmori-de la Puente, Iván Rodríguez-Escolar, Elena Infante González-Mohino, Miguel Pericacho, Rodrigo Morchón
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Animals
Subjects:
angiogenesis
<i>Dirofilaria immitis</i> excretory/secretory antigen
actin
fructose-bisphosphate aldolase
VEGF-A
sVEGFR-2
Online Access:https://www.mdpi.com/2076-2615/14/23/3371
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