Language function improvement and cortical activity alteration using scalp acupuncture coupled with speech-language training in post-stroke aphasia: A randomised controlled study by Bingbing Lin, Jinglei Ni, Xiao Xiong, Lanlan Zhang, Jian Song, Mengxue Wang, Linsong Chai, Yunshi Huang, Jia Huang

“…Results: The acupuncture group showed significant improvements in WAB subscales (Spontaneous Speech, Comprehension, Repetition, Naming, and AQ) with all changes statistically significant (P < 0.001). …”
Get full text

Failure to repair damaged NAD(P)H blocks de novo serine synthesis in human cells by Adhish S. Walvekar, Marc Warmoes, Dean Cheung, Tim Sikora, Najmesadat Seyedkatouli, Gemma Gomez-Giro, Sebastian Perrone, Lisa Dengler, François Unger, Bruno F. R. Santos, Floriane Gavotto, Xiangyi Dong, Julia Becker-Kettern, Yong-Jun Kwon, Christian Jäger, Jens C. Schwamborn, Nicole J. Van Bergen, John Christodoulou, Carole L. Linster

“…For instance, the reduced forms of the central metabolic cofactors nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH), can be converted into redox-inactive products, NADHX and NADPHX, through enzymatically catalyzed or spontaneous hydration. The metabolite repair enzymes NAXD and NAXE convert these damaged compounds back to the functional NAD(P)H cofactors. …”
Get full text

Efficacy of TIPS plus extrahepatic collateral embolisation in real-world data: a validation study by Chao Chen, Feng Zhang, Hao Wu, Wei Wu, Hui Xue, Yuzheng Zhuge, Chunqing Zhang, Guangchuan Wang, Zhengjie Li, Qiong Wu, Bo Wei, Jun Tie, Xiubin Sun, Lianhui Zhao, Yifu Xia, Jiao Xu, Peijie Li

“…Significantly, TIPS+E also reduced rebleeding, HE and FDC in subgroup of using 8 mm diameter stents and embolising of gastric varices+spontaneous portosystemic shunts (GV+SPSS). However, there were no differences in overall or subgroup survival analysis. …”
Get full text

Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats by Judith R. A. van Rooij, Judith R. A. van Rooij, Monica van den Berg, Monica van den Berg, Tamara Vasilkovska, Johan Van Audekerke, Johan Van Audekerke, Lauren Kosten, Daniele Bertoglio, Daniele Bertoglio, Mohit H. Adhikari, Mohit H. Adhikari, Marleen Verhoye, Marleen Verhoye

“…Therefore, we aimed to compare and unravel the sex-specific impact of these dietary interventions on spontaneous brain activity.MethodsHere, we used resting-state fMRI to investigate functional connectivity (FC) changes in five prominent resting-state brain networks (RSNs) in healthy 4 month old male and female F344 rats supplemented to either 40% CR or daily Rsv supplementation (10 mg/kg, oral) for the duration of 1 month.ResultsOur results demonstrated a decreased body weight (BW) in CR rats, as well as an increase in body weight in male Rsv supplemented rats, compared to female Rsv supplemented rats, whereas this difference between sexes was not observed in the control or CR groups. …”
Get full text

Fingerprints of surface flows on solid substrates ablated by phase change: from laboratory experiments to planetary landscapes by Carpy, Sabrina, Berhanu, Michael, Chaigne, Martin, Courrech du Pont, Sylvain

“…In nature, the positive feedback between geometry and mass transfer drives the spontaneous formation of characteristic patterns at different scales. …”
Get full text

Antidepressant- and Anxiolytic-like Effects in Mice of Alkaloids from Aerial Parts of <i>Argemone platyceras</i> Link & Otto by Mayra Beatriz Gómez-Patiño, Rosa Estrada-Reyes, Héctor Hugo Hernández-Mendoza, Ángela Suarez-Rojas, Daniel Arrieta-Baez

“…<b>Results:</b> AlkExt was analyzed using mass spectrometry techniques (DI-ESI and UHPLC-MS) to detect 2,3′,4,5′-Tetramethoxystilbene (<i>m</i>/<i>z</i> 301.14, 3%), scoulerine (<i>m</i>/<i>z</i> 328.16, 19.8%), tetrahydro-columbamine (<i>m</i>/<i>z</i> 342.17, 28.8%), 8-(hydroxymethyl)-2,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-1,11-diol (<i>m</i>/<i>z</i> 358.17, 22.8%), and glaucine (<i>m</i>/<i>z</i> 356.19, 11.1%); these were assayed in a single oral administration of AlkExt, which caused robust anxiolytic- and antidepressant-like effects without affecting the spontaneous ambulatory activity of the mice. <b>Conclusions:</b> The easy and standardized AlkExt analyzed in pharmaceuticals assays in this study strongly suggest its therapeutic potential to treat the comorbidity of anxiety and depression disorders and support further investigations in people with these diseases.…”
Get full text

Outcome from out-of-hospital cardiac arrest managed by the pre-hospital emergency medical system in Martinique, a French Caribbean Overseas Territory by Florian Negrello, Jonathan Florentin, Romain Jouffroy, Vianney Aquilina, Rishika Banydeen, Rémi Neviere, Dabor Resiere, Moustapha Drame, Papa Gueye

“…Secondary outcomes were return of spontaneous circulation (ROSC) prior to hospital admission and causes of cardiac arrest in patients with ROSC. …”
Get full text

Comparison of live birth rate and fetal outcomes between fresh embryo and frozen-thawed embryo transfers: a prospective study by Seyedeh Farinaz Fattahpour, Parvin Hakimi, Fatemeh Tabatabaei, Mahsa Hejazad, Maryam Amoozadeh, Leila Sadeghi, Negin Rezaie, Razih Vejdani, Hosein Azizi

“…The incidence of multiple pregnancies and spontaneous abortion was (5% vs. 13.8%) and (22.2% vs. 30.2%) in the fresh embryo and frozen embryo groups, respectively. …”
Get full text

Comparative Analysis of Adverse Drug Reactions Associated with Fluoroquinolones and Other Antibiotics: A Retrospective Pharmacovigilance Study by Alshareef H, Alenzi KA, Albalawi BR, Alanazi RM, Albalawi NS, Alasoufi WS, Alqifari S, Ahmed R, Ali MAS

“…This study assessed the rate, severity, seriousness, outcomes, and types of FQs adverse drug reactions (ADRs) in reports submitted to a regional spontaneous ADR database.Methods: This was a retrospective cross-sectional observational study involving all patients with reported ADRs related to FQs or other antibiotics (ABs) that were submitted to the Regional Pharmacovigilance Center (PVC) database between January 2019 and December 2022. …”
Get full text

Does providing atrial fibrillation patients, after pulmonary vein isolation, with a 1-lead ECG device relieve the emergency department?-A historically controlled prospective trial. by Jasper L Selder, Mark J Mulder, Willem R van de Vijver, Philip M Croon, Leontine E Wentrup, Stéphanie L van der Pas, Jos W R Twisk, Igor I Tulevski, Albert C Van Rossum, Cornelis P Allaart

Get full text

The effect of hyoscine butyl bromide on the active phase of labour among primiparous women delivered at the Jos University Teaching Hospital by George OC, Ajang MF, Anyaka CU

“…Results: Ninety-seven women had spontaneous vaginal delivery, 18 had Caesarean Sections and 5 had operative vaginal delivery. …”
Get full text

Adrenal hemorrhage in neonates: Incidence, perinatal characteristics and follow-up outcomes by Tek-Jū Tân, Yi-Li Hung, Chung-Min Shen, Wu-Shiun Hsieh

“…Neonatal jaundice was the major comorbidity. All infants had spontaneous resolution of AH before 7 months of age.…”
Get full text

Effect and Mechanism of Catalpol on Behavior in Rats with Post-stroke Depression by WANG Xiangyu, ZHOU Xia, LIU Ju, LIU Fuhong, ZHANG Jiale, SUN Liping, LI Wanbin

“…In the elevated plus maze measurement, the OE% and OT% were significantly increased in the catalpol intervention group on the 4th and 7th day after intervention, and the differences were significant (<italic>P</italic>&lt;0.05), indicating that the catalpol could significantly increase the spontaneous activity of rats and relieve depression-like behavior. …”
Get full text

Integrative Bioinformatics Analysis of Pyroptosis-Related Genes and Analysis of Immune Cell Infiltration in Infantile Hemangioma Regression by Liu L, Lin S, Bai J, Zhang B

“…Lan Liu,1,2,&ast; Sheng Lin,1,2,&ast; Jianxi Bai,1,2 Bing Zhang1,2 1Pediatric Surgery Department, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), Fuzhou City, Fujian Province, People’s Republic of China; 2Pediatric Surgery Department, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou City, Fujian Province, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jianxi Bai, Pediatric Surgery Department, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), 966 hengyu Road, Jinan District, Fuzhou City, Fujian Province, People’s Republic of China, Tel +8615806032159, Email bjxqqq@126.comBackground: Infantile hemangiomas (IHs) are characterized by spontaneous regression, and their pathogenesis involves immune cell infiltration and programmed cell death. …”
Get full text

Preparation of coal kaolinite composites and study of adsorption properties by Rui LIU, Yuping FAN, Ruifeng GUO, Xianshu DONG, Xiaomin MA

“…The adsorption kinetics and thermodynamics showed that the adsorption of Pb(II) ions by the composites conformed to the quasi-secondary kinetic model and Langmuir isotherm model, and it was a monomolecular-layer, chemisorption-dominated, heat-absorbing and spontaneous process with a maximum equilibrium adsorption capacity of 195.37 mg/g. …”
Get full text

Impact of Different Serum Potassium Levels on Postresuscitation Heart Function and Hemodynamics in Patients with Nontraumatic Out-of-Hospital Cardiac Arrest by Yan-Ren Lin, Yuan-Jhen Syue, Tsung-Han Lee, Chu-Chung Chou, Chin-Fu Chang, Chao-Jui Li

“…Sustained return of spontaneous circulation (ROSC) can be initially established in patients with out-of-hospital cardiac arrest (OHCA); however, the early postresuscitation hemodynamics can still be impaired by high levels of serum potassium (hyperkalemia). …”
Get full text

Global regional and national burden of intracerebral hemorrhage between 1990 and 2021 by Zhao-wei Wang, Mei-ping Wan, Jia-hui Tai, Yong Wang, Min-yi Yin

“…Abstract Intracerebral hemorrhage (ICH) represents one of the most devastating forms of stroke, characterized by spontaneous bleeding into the brain parenchyma. This neurological emergency carries a substantial burden of mortality and long-term disability worldwide. …”
Get full text

Profile of postpartum patients with urinary retention at Koja Regional Hospital, Jakarta, Indonesia by Suskhan Djusad, Alfa Putri Meutia, Surahman Hakim

“…ABSTRACT Objective: Postpartum urinary retention (PPUR) is a common voiding disorder, defined as the inability to void spontaneously within 6 hours after delivery with a residual bladder volume exceeding 200 mL. …”
Get full text

Att bevisa målbildsuppsåt vid penningtvättsbrott – möjligheter och svårigheter by Jussi Karkkulainen

“…Money laundering is typically a drawn-out process as opposed to a spontaneous crime. This makes it challenging to recognise whether the offender has, at a certain moment, considered the definitional circumstance of his or her target. …”
Get full text

The Pattern of mRNA Expression Is Changed in Sinoatrial Node from Goto-Kakizaki Type 2 Diabetic Rat Heart by F. C. Howarth, M. A. Qureshi, P. Jayaprakash, K. Parekh, M. Oz, H. Dobrzynski, T. E. Adrian

“…Rats aged 12-13 months were employed in these experiments. Results. Isolated spontaneous heart rate was reduced in GK heart (161 ± 12 bpm) compared to controls (229 ± 11 bpm). …”
Get full text