In silico studies concerning the cytotoxic potential and the inhibition of cytochrome P450 of some bioactive compounds present in Asphodeline lutea root extracts by Irina Lazarova, Emilio Mateev, Gökhan Zengin

“…The goal of our investigation was to determine the physicochemical and pharmacokinetic properties, possible inhibition against CYP450 isoenzymes, and probable cytotoxic effect of some bioactive components isolated from A. lutea roots using in silico methods. Methods: The Absorption, distribution, metabolism, and excretion (ADME) profiles were determined using the freely available SwissADME server. …”
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Diagnostic gaps in vulvar diseases from referral to final diagnosis in a specialized center: analysis of pathways and recommendations for enhancing future diagnostic accuracy by Cornelia Betschart, Tharani Thillainathan, Vera Berger, Isabel Kolm, Brigitte Leeners

“…A systematic diagnostic approach, including symptom evaluation, clinical inspection and appropriate diagnostic testing, is lacking. Standardized methods for symptom documentation, clinical assessment, diagnostic testing, and collaboration with specialized vulvar centers are essential to streamline the precision and efficiency of diagnosis as a basis for optimized treatment strategies. …”
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Outcomes of cemented and uncemented stem fixation in Vancouver B1 periprosthetic femur fractures treated with locking plates by Sezer Astan, Orhan Balta

“…Materials and methods This retrospective analysis included 41 (28 females and 13 males) patients who were treated between 2008 and 2020. …”
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Impact of the COVID-19 pandemic on chest CT scans utilization in Fars province, Iran: an interrupted time series analysis by Mohsen Bayati, Farhad Lotfi, Mohammad Bazyar

“…Conclusions As it is not clear what percent of chest CTs after COVID-19 are really necessary, the findings highlight the need for regulatory policies to optimize CT utilization, reducing unnecessary scans and associated costs while ensuring effective patient care.…”
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Restoring Control: Real-World Success with Imipenem–Relebactam in Critical MDR Infections—A Multicenter Observational Study by Andrea Marino, Giuseppe Pipitone, Emmanuele Venanzi Rullo, Federica Cosentino, Rita Ippolito, Roberta Costa, Sara Bagarello, Ylenia Russotto, Chiara Iaria, Bruno Cacopardo, Giuseppe Nunnari

“…Statistical analysis involved descriptive methods and correlation analysis for mortality predictors. …”
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Analysing the psychological capital influence on academic performance in an e-learning environment by Lama Sameer Khoshaim

“…Hope enhances problem-solving and adaptability, while optimism fosters a proactive attitude and perseverance, both vital for academic excellence. …”
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Removing metals concentration in water and common carp using sheet type adsorbent reared in modified aquarium by N.D. Takarina, N. Matsue, E. Johan, A. Adiwibowo

“…Copper removal in water ranged from 49.12 to 55.56 percent, while removal in carp ranged from 8.08 to 52.33 percent. …”
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CO39 | Artificial intelligence in hemophilia management: challenging the need for experts

“…The integration of AI into clinical practice should be carefully assessed to ensure optimal patient outcomes while preserving the irreplaceable experience and judgment of medical specialists.   …”
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The P Balasubramaniam Award-2024 Singapore Orthopaedic Association Annual Scientific Meeting Award: Novel artificial intelligence algorithm for soft tissue balancing and bone cuts... by Matthew Song Peng Ng, Ryan Wai Keong Loke, Melvin Kian Loong Tan, Yau Hong Ng, Zi Qiang Glen Liau

“…We aim to demonstrate the effectiveness of our novel algorithm in terms of accuracy and surgical duration. Methods We developed a novel AI computational algorithm to optimize rTKA implant positioning in three-dimensional space. …”
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Clinical performance and cost-effectiveness of low-shrinkage giomer resin composite versus resin-modified glass ionomer in cervical carious lesions: a 12-month randomized controlle... by Menna El Ghamrawy, Dina Kamal, Heba Hamza

“…Participants and methods A total of 56 class V cavities were randomly assigned to two groups (n = 28). …”
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Unveiling the perfect workout: exercise modalities and dosages to ameliorate adipokine dysregulation in individuals with overweight and obesity: a systematic review with pairwise,... by Hai Wang, Hao Wang, Enyan Zhan, Xiaodong Liu

“…For leptin levels, COM was the most effective intervention (SMD = −0.99, 95% CrI: −1.48 to −0.51; SUCRA = 84%), followed by AE and HIIT, while RT did not demonstrate a statistically significant effect. …”
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Dataset of apples for grading by sweetness, ripeness and varietyMendeley Data by Shilpa Gaikwad, Sonali Kothari, Ignisha Rajathi G

“…Ripeness evaluation includes 29,160 images documenting the complete maturation cycle over 18 days, while variety classification contains 1683 images from three distinct cultivars. …”
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Dynamic evolutionary game model for coal mine safety monitoring and control and its application by Ruxiang QIN, Tao SHEN, Shihui LI

“…The model takes the strategy changes of the two major subjects as the core, explores the influence of parameter changes on the strategy trend and its convergence state, and proposes the inspection method and reward and punishment system for optimizing monitoring and control. …”
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Placebo-Controlled Trials in the Management of Crohn’s Disease: An Umbrella Review of Meta-Analyses by Richard Silva, José Nunes de Azevedo, Jorge Pereira Machado, Jorge Magalhães Rodrigues

“…More research is needed to confirm the findings and establish optimal treatment strategies. Moreover, while biologic agents show promise, the optimal management of Crohn’s disease requires further research. …”
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Channel and Power Allocation for Multi-Cell NOMA Using Multi-Agent Deep Reinforcement Learning and Unsupervised Learning by Ming Sun, Yihe Zhong, Xiaoou He, Jie Zhang

“…In addition, due to the complex and dynamically changing wireless communication environment and the lack of the near-optimal labels, conventional supervised learning methods cannot be directly applied. …”
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Predictive modeling of oil rate for wells under gas lift using machine learning by Famin Ma, Farag M. A. Altalbawy, Pinank Patel, R. Manjunatha, Rishiv Kalia, Shoira Formanova, P. Raja Naveen, Kamal Kant Joshi, Aashna Sinha, Abdolali Yarahmadi Kandahari, Taqi Mohammed Khattab Al-Rubaye, Mohammad Mahtab Alam

“…Abstract Optimizing oil production in wells employing gas lift systems is a critical challenge due to the complex interplay of operational and reservoir parameters. …”
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Ligation of the Pancreatic Stump With Quantified Force During Distal Pancreatectomy for Postoperative Pancreatic Fistula: Protocol for a Single-Center Nonrandomized Controlled Clin... by Lufeng Chang, Jiongxin Xiong, Ming Yang, Yuxin Yang, Tao Peng, Tao Yin, Heshui Wu, Shanmiao Gou

“…The management of the pancreatic stump is one of the key factors influencing the occurrence of postoperative pancreatic fistula after distal pancreatectomy, but the optimal management approach remains debatable. The main methods for pancreatic stump closure include manual suturing and stapler closure. …”
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Clinical and Diagnostic Efficiency of the Study of the Quality of Life According to the Questionnaires PHEC-22 and Catquest-9SF after Bilateral Cataract Phacoemulsification and Mon... by V. V. Neroev, N. I. Ovechkin

“…The results obtained (taking into account clinical normalization) allow us to recommend the PHEC-22 questionnaire for inclusion in the complex diagnosis of patients with cataracts both before and after surgery in solving a number of urgent problems — a comparative assessment of IOL, a study of the effectiveness of methods for postoperative rehabilitation of patients, the choice of the optimal formula for calculating IOL and some others.…”
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Ethylene scavengers for extended freshness: A critical comparison between physisorption and chemistry process by Yanan Wang, Jingfei Xu, Rinat M. Iskakov, Xicheng Jia

“…This review highlights advancements in ethylene removal technologies tailored for fruit and vegetable (F&V) preservation, with a focus on physical adsorption and chemical elimination methods. Conventional approaches, such as potassium permanganate (KMnO₄) and 1-methylcyclopropene (1-MCP), are limited by toxicity concerns, declining efficiency, and potential fruit disorders. …”
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Blood Urea Nitrogen as a Predictor of Severe Acute Pancreatitis Based on the Revised Atlanta Criteria: Timing of Measurement and Cutoff Points by Suhan Lin, Wandong Hong, Zarrin Basharat, Qipin Wang, Jingye Pan, Mengtao Zhou

“…This study evaluated the prognostic accuracy of BUN for severe acute pancreatitis (SAP) and in-hospital mortality (IHM) in terms of the best timing for BUN measurement and the optimal BUN cutoff points. Methods. BUN determinants at the time of admission and 24 hrs after hospital admission were recorded and analyzed statistically. …”
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