A bacteriophage-based virus-like particle vaccine induces cross-reactive neutralising antibodies against porcine epidemic diarrhoea viruses (PEDV) by Jixiang Gu, Xu Zheng, Chunhui Li, Shipeng Wang, Xiangyu Xie, Martin F. Bachmann, Yuchen Nan, Liang Li, Pei Sun, Lisha Zha, Xinyue Chang

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Stabilization of norovirus GII.3 virus-like particles by rational disulfide engineering by Christopher Warren, Jennifer D. Galli, Karin Bystol, Gregory O’Donnell, Andrew R. Swartz, Emily A. Dewar, Corey May Fulton, Pamela Shen, Estibaliz Gonzalez-Fernandez, Lizzy Aurora DeWitt, Uijin Jeong, Oscar Chi-Chien Pan, Sean Miller, Arthur Fridman, Courtney David, Zhifeng Chen, Jiajie Wei

“…The major capsid protein, VP1, can self-assemble into non-infectious virus-like particles (VLPs), representing an attractive vaccine platform. …”
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Raman-based PAT for multi-attribute monitoring during VLP recovery by dual-stage CFF: attribute-specific spectral preprocessing for model transfer by Annabelle Dietrich, Luca Heim, Jürgen Hubbuch 

“…In this study, soft sensors based on Raman spectroscopy and linear or partial least squares (PLS) regression were developed and successfully transferred to a filtration-based recovery step of precipitated virus-like particles (VLPs). For near real-time monitoring of product accumulation and precipitant depletion, the dual-stage cross-flow filtration (CFF) set-up was equipped with an on-line loop in the second membrane stage. …”
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Exposure to COVID-19 virus-like particles modulates firing patterns of cortical neurons in the mouse brain by Aniruddha Das, Jacob Icardi, Julie Borovicka, Sarah Holden, Henry F. Harrison, Alec J. Hirsch, Jacob Raber, Hod Dana

“…However, its high infectivity makes comprehensive research with the active virus challenging. Here, we use virus-like particles (VLPs) to explore how exposure to SARS-CoV-2 proteins affects brain activity patterns in wild-type mice and in mice that express the human tau protein. …”
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Impact of specific productivity and operation mode upon the biophysical properties of HIV-1 Gag-based virus-like particles by Pol Pérez-Rubio, Elianet Lorenzo Romero, Josefina Casas, Andy Díaz-Maneh, Francesc Gòdia, Laura Cervera, Jesús Lavado-García

“…Abstract Virus-like particles (VLPs) are non-infective vaccine candidates that have gained interest given their natural ability to elicit strong immune responses. …”
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Multivalent display of VP28 on chimeric virus-like particles enhances binding to shrimp target tissues: A novel antiviral strategy against white spot syndrome virus by Somkid Jaranathummakul, Pitchanee Jariyapong, Orawan Thongsum, Supawich Boonkua, Charoonroj Chotwiwatthanakun, Monsicha Somrit, Somluk Asuvapongpatana, Attaboon Wathammawut, Wattana Weerachatyanukul

“…This study aimed to evaluate the tissue-binding affinity of full-length VP28 and its derived peptides (P1: Residues 35–65; P2: Residues 66–95) as well as a multimeric chimeric virus-like particle (K5-VLP) displaying VP28 on the surface of Macrobrachium rosenbergii nodavirus capsids to enhance host tissue interaction. …”
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THE RECOMBINANT ANTIGENS FOR VACCINES FOR THE TREATMENT OF PAPILLOMAVIRUS (REVIEW) by M. A. Zhuchenko

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Development of an African horse sickness VP6 DIVA diagnostic ELISA by Munyaradzi Tinarwo, Susan J. Dennis, Inga I. Hitzeroth, Ann E. Meyers, Edward P. Rybicki, Sandiswa Mbewana

“…Previously, our group developed recombinant AHSV serotype 4 and 5 virus-like particle (VLP) vaccine candidates in plants that elicited an immune response in guinea pigs and horses. …”
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