Integrative in Silico modeling for mTOR inhibition: From ridge classifiers to descriptor-free deep neural networks by Seyed Alireza Khanghahi, Hadi Kamkar, Seyedehsamaneh Shojaeilangari, Abdollah Allahverdi, Parviz Abdolmaleki

“…Unlike prior studies that focused on specific algorithms or limited descriptors, we benchmark a wide range of models, from traditional models like Random Forest, logistic regression, and SVM to modern algorithms like CNNs, GRUs, and LSTMs, on both descriptor-based features obtained by Dragon and descriptor-free inputs, including raw SMILES string, and Morgan fingerprints. …”
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Identification and analysis of the endoplasmic reticulum stress hub genes in sepsis-associated ARDS by Ling Gao, Tingting Liu, Xiaoyan Li

“…Endoplasmic reticulum stress (ERS) plays an important role in the pathophysiologic process of sepsis-associated ARDS. …”
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Enhanced identification of Morganella spp. using MALDI-TOF mass spectrometry by Mathilde Duque, Cécile Emeraud, Rémy A. Bonnin, Quentin Giai-Gianetto, Laurent Dortet, Alexandre Godmer

“…Conclusion: Through development of a publicly-available online ML-based classifier, this study has improved the capacity of MALDI-TOF for distinguishing Morganella spp., providing a reliable, user-friendly solution suited to routine clinical diagnostics and supporting a better understanding of the roles of M. morganii and M. sibonii in human pathology.…”
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Causal estimation of the relationship between reproductive performance and the fecal bacteriome in cattle by Yutaka Taguchi, Haruki Yamano, Yudai Inabu, Hirokuni Miyamoto, Koki Hayasaki, Noriyuki Maeda, Yoshiro Kanmera, Seiji Yamasaki, Noboru Ota, Kenji Mukawa, Atsushi Kurotani, Shigeharu Moriya, Teruno Nakaguma, Chitose Ishii, Makiko Matsuura, Tetsuji Etoh, Yuji Shiotsuka, Ryoichi Fujino, Motoaki Udagawa, Satoshi Wada, Jun Kikuchi, Hiroshi Ohno, Hideyuki Takahashi

“…The relationship of the fecal bacteriome at 150 and 300 days of age and reproductive performance was visualized using statistical structural equation modelling between traits based on four types of machine-learning algorithms (linear discriminant analysis, association analysis, random forest, and XGBoost). …”
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Robust Semantic Segmentation of Wafer Transmission Electron Microscopy Image Using Multi-Task Learning With Edge Detection by Yongwon Jo, Jinsoo Bae, Hansam Cho, Sungsu Kim, Heejoong Roh, Kyunghye Kim, Munki Jo, Munuk Kim, Jaeung Tae, Seoung Bum Kim

“…Semantic segmentation for wafer transmission electron microscopy (TEM) images plays a crucial role in the automated measurement of semiconductors. …”
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Development of Smart Models to Accurately Predict Dynamic Viscosity of CO2-Saturated Polyethylene Glycol by Ayat Hussein Adhab, Morug Salih Mahdi, Bhavesh Kanabar, Anupam Yadav, Ranganathaswamy M K, Rishabh Thakur, Parveen Kumar, Braj Krishna, Aseel Salah Mansoor, Usama Kadem Radi, Nasr Saadoun Abd, Samim Sherzod

“…This study, hence, introduces machine learning models utilizing K-nearest neighbors, decision tree, adaptive boosting, multilayer perceptron artificial neural network, convolutional neural network, support vector machine, random forest and ensemble learning algorithms to accurately forecast the dynamic viscosity of CO2-saturated PEG based on PEG molar mass, pressure, and temperature. …”
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Developing a cost-effective tool for choke flow rate prediction in sub-critical oil wells using wellhead data by Zhiwei Xun, Farag M. A. Altalbawy, Prakash Kanjariya, R. Manjunatha, Debasish Shit, M. Nirmala, Ajay Sharma, Sarbeswara Hota, Shirin Shomurotova, Fadhil Faez Sead, Hojjat Abbasi, Mohammad Mahtab Alam

“…Among these, SADE demonstrated superior performance based on metrics such as average absolute relative error (AARE%), R2, and mean squared error (MSE). …”
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Thermal ablation in the management of oligometastatic colorectal cancer by Thierry De Baere, Lambros Tselikas, Alexandre Delpla, Charles Roux, Eloi Varin, Adrian Kobe, Steven Yevich, Frederic Deschamps

“…Ablation outcomes are compared to surgical and radiation therapy literature.Results The application of thermal ablation varies widely based on tumor burden, technical expertise, and local cancer triage algorithms. …”
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Prediction of microbe-drug associations using a CNN-Bernoulli random forest model by Zihao Song, Qingnuo Li, Jincheng Zhao, Qinggang Bu, Zekang Bian, Jia Qu

“…Background Antibiotics play a critical role in treating microbial infections. However, their widespread use has contributed to the growing problem of microbial resistance. …”
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Identification and validation of ubiquitination-related genes for predicting cervical cancer outcome by Ge Jin, Xiaomei Fan, Xiaoliang Liang, Honghong Dai, Jun Wang

“…These findings provide crucial insights into the role of ubiquitination in CC pathogenesis and offer valuable targets for advancing future research and therapeutic strategies.…”
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Conflict management training for future educators by N. A. Sokolova, N. V. Sivrikova, E. G. Chernikova, T. G. Ptashko, E. M. Harlanova, S. V. Roslyakova

“…Most students (97,6%) learned algorithms to solve typical interpersonal conflicts and began to choose more constructive strategies to solve them. …”
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AI for rapid identification of major butyrate-producing bacteria in rhesus macaques (Macaca mulatta) by Annemiek Maaskant, Donghyeok Lee, Huy Ngo, Roy C. Montijn, Jaco Bakker, Jan A. M. Langermans, Evgeni Levin

“…Abstract Background The gut microbiome plays a crucial role in health and disease, influencing digestion, metabolism, and immune function. …”
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Exploring fecal microbiota signatures associated with immune response and antibiotic impact in NSCLC: insights from metagenomic and machine learning approaches by Wenjie Han, Wenjie Han, Yuhang Zhou, Yuhang Zhou, Yiwen Wang, Yiwen Wang, Xiaolin Liu, Tao Sun, Tao Sun, Junnan Xu, Junnan Xu, Junnan Xu

“…KEGG-based functional analysis revealed the enrichment of amino acid metabolism pathways in responders. …”
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Combined impact of semantic segmentation and quantitative structure modelling of Southern pine trees using terrestrial laser scanning by Jinyi Xia, Timothy A. Martin, Gary F. Peter, Kody M. Brock, Jeff W. Atkins, Matthew A. Gitzendanner, Inacio Bueno, Kim Calders, Ana Paula Dalla Corte, Andrew T. Hudak, Monique Bohora Schlickmann, Michael G. Andreu, Caio Hamamura, Carine Klauberg, Carlos A. Silva

“…These findings highlight the importance of selecting segmentation algorithms based on specific research goals, balancing accuracy and computational feasibility in forest structural modeling.…”
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Comparison of methods for resolving the contributions of local emissions to measured concentrations by T. D. Edwards, Y. K. Wong, C.-H. Jeong, J. M. Wang, Y. Su, G. J. Evans

“…Based on our results, we provide ranked recommendations for choosing background estimation methods. …”
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YOLOv8-TF: Transformer-Enhanced YOLOv8 for Underwater Fish Species Recognition with Class Imbalance Handling by Chiranjibi Shah, M M Nabi, Simegnew Yihunie Alaba, Iffat Ara Ebu, Jack Prior, Matthew D. Campbell, Ryan Caillouet, Matthew D. Grossi, Timothy Rowell, Farron Wallace, John E. Ball, Robert Moorhead

“…In video-based fish surveys, species recognition plays a vital role in stock assessments, ecosystem analysis, production management, and protection of endangered species. …”
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A Cross-Sectional Analysis of Oil Pulling on YouTube Shorts by Jun Yaung, Sun Ha Park, Shahed Al Khalifah

“…<b>Methods</b>: On 28 January 2025, a systematic search of YouTube Shorts was performed using the term “oil pulling” in incognito mode to reduce algorithmic bias. English language videos with at least 1000 views were included through purposive sampling. …”
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Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patients by Ran Du, Lijun Jing, Denggang Fu

“…Furthermore, we identify PPP1R8 as a key regulator of GBM cell proliferation and growth, providing insights into the immune microenvironment’s role in GBM progression.…”
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Prediction of Flexural Ultimate Capacity for Reinforced UHPC Beams Using Ensemble Learning and SHAP Method by Zhe Zhang, Xuemei Zhou, Ping Zhu, Zhaochao Li, Yichuan Wang

“…Furthermore, multiple machine learning (ML) algorithms, including both traditional and EL models, are employed to develop optimized predictive models for the flexural ultimate capacity of reinforced UHPC specimens derived from the established database. …”
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Comprehensive analysis of regulatory B Cell related genes in prognosis and therapeutic response in lung adenocarcinoma by Liangyu Zhang, Liangyu Zhang, Jianshen Zeng, Jianshen Zeng, Xun Zhang, Xun Zhang, Menglong Zhang, Menglong Zhang, Yilin Lin, Yilin Lin, Fancai Lai, Fancai Lai

“…BackgroundRegulatory B cells (Bregs) are a distinct subset of B cells that play a crucial role in regulating immune responses and maintaining immune tolerance in cancerous environments. …”
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