Extracellular matrix remodeling in patients with ischemic chronic heart failure with preserved ejection fraction by V. D. Syvolap, D. A. Lashkul

“…It was established that imbalance in the system MMP/TIMP in ischemic heart failure with preserved left ventricular ejection fraction leads to disruption of the extracellular matrix structural functional sufficiency, increases functional failure and is associated with impaired renal function. …”
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Imaging in Heart Failure with Preserved Ejection Fraction: A Multimodality Imaging Point of View by Serkan Ünlü, Özge Özden, Ahmet Çelik

“…HFpEF is an extremely complex syndrome and multimodality imaging is important for diagnosis, identifying its different phenotypes and determining prognosis. Evaluation of left ventricular filling pressures using echocardiographic diastolic function parameters is the first step of imaging in clinical practice. …”
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State of precision medicine for heart failure with preserved ejection fraction in a new therapeutic age by Roy Rasalam, Andrew Sindone, Gary Deed, Ralph G. Audehm, John J. Atherton

“…Two algorithms, the ‘Heavy, 2 or more Hypertensive drugs, atrial Fibrillation, Pulmonary hypertension, Elderly age >60, elevated Filling pressures’ (H2FPEF) and the ‘Heart Failure Association Pre‐test assessment, Echocardiography and natriuretic peptide, Functional testing, Final aetiology’ (HFA‐PEFF), can help to determine the likelihood of HFpEF in individuals with symptoms of HF. …”
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Left Ventricular Systolic Dysfunction Due to Atrial Fibrillation: Clinical and Echocardiographic Predictors by Erez Marcusohn, Ofer Kobo, Maria Postnikov, Danny Epstein, Yoram Agmon, Lior Gepstein, Yaron Hellman, Robert Zukermann

“…Results: Of 482 patients included in the final analysis, 80 (17%) had reduced and 402 (83%) had preserved LV function during the precardioversion transoesophageal echocardiography. …”
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NEW EMPHASES ON THE STUDY OF THE PATHOGENESIS OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION: FOCUS ON INFLAMMATORY MARKERS by O. M. Drapkina, L. O. Palatkina

“…It makes conduct active searches for new biological markers of diastolic heart function. Participation of proinflammatory cytokines, in particular GDF-15, in the process of elasticity reduction and relaxation disorders of left ventricular myocardium, may be of great importance in the development of new medical agents designed to delay the progression of CHF with preserved ejection fraction.…”
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Myocardial electrical activity according to daily ECG monitoring in patients with heart failure with preserved ejection fraction and asymptomatic diastolic dysfunction by V. D. Syvolap, Ya. V. Zemlyaniy, E. V. Nazarenko

“…For evaluating changes in the electrical activity of the myocardium and study their relationship with those structural and functional condition of the heart in 36 patients with preserved left ventricular ejection fraction after myocardial infarction with hypertension the next methods were used: ECG monitoring, echocardiography and serum NTproBNP level detection. …”
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The oxytocin-oxytocin receptors system — a new pathogenetic mechanism in the development of diabetic phenotype of heart failure with preserved ejection fraction in women by A. D. Starchenko, Yu. V. Liskova, A. A. Stadnikov

“…To determine the pathogenetic role of the oxytocinergic system in the development of myocardium structural and functional changes in women with heart failure with preserved ejection fraction (HFpEF) associated with type 2 diabetes mellitus (DM2T) (diabetic phenotype of HFpEF).Material and methods. …”
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Therapeutic Efficacy of Alpha-Lipoic Acid against Acute Myocardial Infarction and Chronic Left Ventricular Remodeling in Mice by Zequan Yang, Yikui Tian, Stuart S. Berr, Brent A. French

“…Daily oral ingestion of ALA not only protects mice against AMI but also attenuates LVR and preserves contractile function in the months that follow.…”
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DIABETIC CARDIOMYOPATHY. RESISTIN: A CONTROL OF A MYOCARDIAL HYPERTROPHY by An. A. Aleksandrov, O. A. Shatskaya, S. S. Kuharenko, M. N. Yadrihinskaya, E. N. Abdalkina, E. N. Drozdova, M. V. Shestakova

“…To evaluate the association of serum resistin with morphological and functional indices of hypertrophic myocardium in patients with type 2 diabetes and chronic heart failure (CHF) with preserved left ventricular ejection fraction.Material and methods. …”
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Diabetes mellitus aggravates myocardial inflammation and oxidative stress in aortic stenosis: a mechanistic link to HFpEF features by Melissa Herwig, Marcel Sieme, Andrea Kovács, Muchtiar Khan, Andreas Mügge, Wolfgang E. Schmidt, Ferhat Elci, Shan Sasidharan, Peter Haldenwang, Jan Wintrich, Benjamin Sasko, Ibrahim Akin, Máthé Domokos, Francesco Paneni, Ibrahim El-Battrawy, Zoltán V. Varga, Francisca Saraiva, Adelino F. Leite-Moreira, Péter Ferdinandy, Loek van Heerebeek, Inês Falcão-Pires, Nazha Hamdani

“…This study aimed to investigate the effects of DM on the left ventricle in AS patients, specifically focusing on the inflammatory response, oxidative stress, and their implications for cardiomyocyte function, titin phosphorylation, and the nitric oxide (NO)-soluble guanylyl cyclase (sGC)-cyclic guanosine monophosphate (cGMP)-protein kinase G (PKG) signaling pathway. …”
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ALCAPA Presents in an Adult with Exercise Intolerance but Preserved Cardiac Function by Yan Liu, Beth W. Miller

“…She had normal left ventricular function without apparent ischemic cardiac symptoms eighteen months after procedure.…”
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Dysregulated inflammation, oxidative stress, and protein quality control in diabetic HFpEF: unraveling mechanisms and therapeutic targets by Simin Delalat, Innas Sultana, Hersh Osman, Marcel Sieme, Saltanat Zhazykbayeva, Melissa Herwig, Heidi Budde, Árpád Kovács, Mustafa Kaçmaz, Eda Göztepe, Natalie Borgmann, Gelareh Shahriari, Benjamin Sasko, Jan Wintrich, Peter Haldenwang, Wolfgang E. Schmidt, Wiebke Fenske, Muchtiar Khan, Kornelia Jaquet, Andreas Mügge, Domokos Máthé, Viktória E. Tóth, Zoltán V. Varga, Péter Ferdinandy, Ibrahim El-Battrawy, Loek van Heerebeek, Nazha Hamdani

“…Methods We conducted an analysis of left ventricular myocardial tissue from HFpEF patients, both with and without diabetes, employing a range of molecular, biochemical, and functional assays. …”
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Severe Left Ventricular Hypertrophy, Small Pericardial Effusion, and Diffuse Late Gadolinium Enhancement by Cardiac Magnetic Resonance Suspecting Cardiac Amyloidosis: Endomyocardia... by Nina P. Hofmann, Sorin Giusca, Karin Klingel, Peter Nunninger, Grigorios Korosoglou

“…Here, we present a case of a patient with severe LV hypertrophy (septal wall thickness of 23 mm, LV mass of 264 g, and LV mass index of 147 g/m2), severely impaired longitudinal function, and preserved radial contractility (ejection fraction = 55%), accompanied by small pericardial effusion and diffuse late gadolinium enhancement (LGE) by cardiac magnetic resonance (CMR). …”
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THE LEFT VENTRICLE DIASTOLIC FUNCTION IN PATIENTS WITH HYPERTENSION UNDER THE USE OF DIFFERENT DRUG GROUPS by A. V. Budnevskij, E. S. Ovsjannikov, L. E. Kulikova

“…Materials and methods: 82 patients (58 women and 24 men) with stage 2 hypertension were examined. The diastolic function was assessed via echocardiography in accordance with the European Association of Cardiovascular Imaging guidelines (2017). …”
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Characteristics of patients with chronic heart failure with mildly reduced ejection fraction: clinical and demographic aspect by M. T. Duishenalieva, A. G. Polupanov, F. T. Rysmatova, E. Zh. Myrzabekova, N. E. Esenbekova, N. Ch. Cholponbekova, E. Sh. Altymyshova, A. T. Arykova, N. B. Cheskidova, E. D. Djyshambaev

“…Type 2 diabetes mellitus was present in approximately one in five patients, regardless of the CHF phenotype. Patients with functional class III (NYHA) predominated among those with HFmrEF (54,5 %) and HFrEF (56,3 %).Conclusion. …”
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Right ventricular visualization at SPECT perfusion imaging before and after revascularization in patients with postinfarction cardiosclerosis by E. N. Ostroumov, E. V. Migunova, E. D. Kotina, E. B. Leonova, I. M. Kuzmina, M. V. Parkhomenko, S. Yu. Kambarov, M. A. Sagirov

“…Globally, only an improvement in the diastolic function of the left and right ventricles was noted in the latter group of patients. …”
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Endothelial Microvascular Dysfunction and Its Relationship with Haptoglobin Levels in Patients with Different Phenotypes of Chronic Heart Failure by V. I. Podzolkov, N. A. Dragomiretskaya, I. G. Beliaev, Ju. S. Kucherova, A. V. Kazadaeva

“…Patients with different phenotypes of functional class II-IV chronic heart failure according to NYHA (n=80) underwent a general clinical examination, determination of the serum haptoglobin level by enzyme-linked immunosorbent assay, as well as an assessment of the MC state on the medial surface of the upper third of the leg by laser Doppler flowmetry (LDF).Results. …”
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STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELS by M. A. Kondratyuk, O. M. Radchenko

“…The patients with the highest MMM levels were specified by low left ventricular ejection fraction (p<0.05), the largest size of right ventricle, the lowest rate of preserved left ventricular function and high rate of diagnosis of increased sizes of the left atrium, interventricular septum and right ventricle.Conclusion. …”
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Multiparity induces persistent myocardial structural, functional and transcriptomic remodelling in mice by Ruth R. Magaye, Bing H. Wang, Hongyi R. Liu, Shanae Bailey, Rithy Nuon, Sabrina Sutano, Michael Nyugen, Helen Kiriazis, Kyah Grigolon, Luchen Shan, William W. H. Ho, Fumihiko Takeuchi, Daniel G. Donner, David M. Kaye

“…We evaluated blood pressure, body composition, gross weight and histologic cardiac structure. Cardiac function was assessed by echocardiography together with transcriptomic analysis of the left ventricular myocardium. …”
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Galectin-3 as a Marker of Cardiorenal Syndrome in Patients with Chronic Heart Failure by V. I. Podzolkov, N. A. Dragomiretskaya, A. V. Kazadaeva, Yu. G. Belyaev, A. V. Tolmacheva

“…Galectin-3 level in patients with HF is more influenced by the degree of reduction in GFR rather than the left ventricular systolic function impairment.…”
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