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81
Genetic heterogeneity in familial forms of genetic generalized epilepsy: from mono- to oligogenism
Published 2024-11-01“…Moreover, a polygenic mode of inheritance is suspected in most cases. We performed SNP microarrays and whole exome sequencing in 20 families from Sudan, focusing on those with at least four affected members. …”
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82
Identificación de biomarcadores sanguíneos para la detección de lesiones premalignas y el diagnóstico del cáncer gástrico
Published 2017-03-01“…La sangre se colocó en un tubo de ARN sanguíneo PAXgene; luego, el ARN se extrajo de la sangre y se analizó usando una plataforma de microarrays, los cuales identificaron cambios de expresión de ARN mensajero que permitieron diferenciar cada una de las etapas descritas. …”
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83
HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma
Published 2025-08-01“…By integrating the largest publicly available single‐cell RNA sequencing (scRNA‐seq) dataset of HCC (160 samples from 124 patients) with multi‐scale protein‐level validation using multiplex immunofluorescence and tissue microarrays (198 HCC specimens), HLA‐DR⁺ tumor cells are identified as a distinctive feature of HBV+HCC. …”
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84
Vitamin K‐dependent gamma‐carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGF...
Published 2025-01-01“…Methods Analysis of pancreatic ductal adenocarcinoma (PDAC) datasets, including transcription profiles, clinical data, and tissue microarrays, was conducted to evaluate PRRG1 expression and its clinical relevance. …”
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85
Gene Expression Profiles for Predicting Metastasis in Breast Cancer: A Cross-Study Comparison of Classification Methods
Published 2012-01-01“…Machine learning has increasingly been used with microarray gene expression data and for the development of classifiers using a variety of methods. …”
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86
Gene Expression Music Algorithm-Based Characterization of the Ewing Sarcoma Stem Cell Signature
Published 2016-01-01“…We analyzed the behavior of public microarray data sets from Ewing sarcoma (“Ewing family tumors,” EFT) cell lines and biopsies in GEMusicA after prefiltering DNA microarray data for the probe sets from the stem cell signature. …”
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87
Deep learning-based spatial analysis on tumor and immune cells of pathology images predicts MIBC prognosis.
Published 2025-01-01“…The prognostic value of Lymph_inside % was validated in the HBlaU079Su01 microarray. Multiomics analysis demonstrated that Lymph_inside % demonstrated significant positive correlations with antitumor immune cell abundance and the apoptosis pathway. …”
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88
Assessing the suitability of formalin-fixed paraffin-embedded (FFPE) tissue for genome-wide association studies (GWAS)
Published 2025-07-01“…This, together with the lower cost of genotyping and computational efficiency, makes microarray technology currently the superior method for GWAS using FFPE tissue. …”
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89
D-Mannose Inhibits Adipogenic Differentiation of Adipose Tissue-Derived Stem Cells via the miR669b/MAPK Pathway
Published 2020-01-01“…The microarray data were further analyzed by a Venn diagram and Gene Set Enrichment Analysis (GSEA). …”
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90
The Comparison of Three Measures in Feature Selection
Published 2018-02-01“…By combining them with the fast correlation-based filter ( FCBF) feature selection method,we make the comparison of selected feature subset from 8 gene microarray and image datasets. Experimental results indicate that the feature subsets selected by linear correlation coefficient based FCBF obtain better classification accuracy in gene microarray datasets than in image datasets,while mutual information and symmetrical uncertainty based FCBF tend to obtain better results in image datasets. …”
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91
CFS-MOES Ensemble Model on Metaheuristic Search-Based Feature Selection
Published 2024-01-01“…However, the tremendous dimensionality of the microarray cancer dataset is the greatest challenge in interpreting the data. …”
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92
Identification of Potential Therapeutic Targets in the Liver of Pioglitazone-Treated Type 2 Diabetes Sprague-Dawley Rats via Expression Profile Chip and iTRAQ Assay
Published 2018-01-01“…Furthermore, Western blotting and RT-qPCR were used to validate the results of microarray and iTRAQ. In conclusion, Cyp7a1, Cp, and RT1-EC2 are differentially expressed genes/proteins since they showed a similar trend in rats in the model group and the pioglitazone-treated group.…”
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93
Inhibition of Rho Kinase Induces Antioxidative Molecules and Suppresses Reactive Oxidative Species in Trabecular Meshwork Cells
Published 2017-01-01“…The cynomolgus monkey array and 12,613 probes were used in DNA microarray analysis, and the affected genes were categorized using gene ontology analysis. …”
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94
Transcriptional Profiling of Caudal Fin Regeneration in Zebrafish
Published 2006-01-01“…To elucidate the principles of limb-fin regeneration, we performed an Affymetrix microarray screen on regenerating caudal fins 12, 24, 48, and 72 h post amputation. …”
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95
Identification of Differentially Expressed Genes and Long Noncoding RNAs Associated with Parkinson’s Disease
Published 2019-01-01“…This study aims to determine differentially expressed genes (DEGs) and long noncoding RNAs (lncRNAs) associated with Parkinson’s disease (PD) using a microarray. Methods. We downloaded the microarray data GSE6613 from the Gene Expression Omnibus, which included 105 samples. …”
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96
Knockdown of USF1 and USF2 drives prolonged changes in the gene expression response of M12-5B3 cells to DNA damage.
Published 2025-01-01“…Gene ontology analyses revealed that USF knockdown induced numerous changes in the expression of genes critical for immune development and function while diminishing the responsiveness of genes linked to DNA damage pathways. Microarray findings were confirmed by RT-qPCR for a panel of genes responsive to USF knockdown and/or irradiation. …”
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97
Performance and clinical implications of non-invasive prenatal testing for rare chromosomal abnormalities: a retrospective study of 94,125 cases
Published 2025-08-01“…Concurrent use of karyotyping and chromosome microarray analysis, rather than karyotyping alone, mitigates culture-related bias and enhances the PPV. …”
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98
Expression of Biomarkers CXCR4, IL11-RA, TFF1, MLF1P in Advanced Breast Cancer Patients with Bone Metastatic: a Diagnostic Study
Published 2017-02-01“…Immunohistochemistry and microarray analysis was performed in 81 formalin fixed paraffin embedded (FFPE) samples from 81 patients were used. …”
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99
A Review on the Application of Organoids in Food Science Research
Published 2025-06-01“…This paper introduces the current status of the construction and functional characterization of three major organoids, namely, intestinal, liver and brain organoids, describes recent progress in the application of intestinal, liver and brain organoids in the field of food science, discusses future prospects for the integrated application of organoids with cutting-edge technologies such as microarray technology and microfluidics, and analyzes the challenges and future directions for the application of organoid models in food science. …”
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100
The expression levels of CYP3A4 and CYP3A5 serve as potential prognostic biomarkers in lung adenocarcinoma
Published 2017-04-01“…Here, we explored the prognostic value of CYP3A4 and CYP3A5 in lung adenocarcinoma. The tissue microarray was made up of lung adenocarcinoma samples and corresponding normal lung tissues from Nanjing Medical University affiliated Cancer Hospital Tissue Bank. …”
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