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Lactylation-mediated miRNA regulation in cancer therapy resistance
Published 2025-08-01“…Based on these converging mechanisms, we highlight potential therapeutic strategies, including the co-targeting of LDHA and oncogenic miRNAs (e.g., nanoparticle-mediated delivery of anti-miR-21), as well as liquid biopsy-based monitoring of circulating H3K18la and miRNA signatures to predict emerging resistance. …”
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Unlocking the potential of miRNAs in detecting pulmonary tuberculosis: prospects and pitfalls
Published 2024-01-01“…The review assesses the advantages and obstacles associated with miRNA-based diagnostic biomarkers in pulmonary TB and facilitates rapid, point-of-care testing.…”
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Presymptomatic microRNA-based biomarker signatures for the prognosis of localized radiation injury in mice.
Published 2025-01-01“…In this study, we sought to identify early miRNA signatures for LRI severity prognosis before clinical symptoms appear. …”
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Development and validation of G2M signature-based prognostic model for stratifying colon cancer prognosis
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Identification of a LncRNA based CeRNA network signature to establish a prognostic model and explore potential therapeutic targets in gastric cancer
Published 2025-07-01“…Differentially expressed RNAs, including lncRNA, miRNA, and mRNA, in cancerous and adjacent non-cancerous tissues were analyzed using Weighted correlation network analysis (WGCNA) and construction of a lncRNA-miRNA-mRNA competing endogenous RNA (ceRNA) network. …”
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Circulating miR‐144‐3p as a Novel Independent Biomarker Associated With Low Muscle Strength Among Older Adults
Published 2025-08-01“…We aimed to examine distinct miRNA signatures associated with muscle mass, strength, and performance and to explore independent biomarkers for identifying older adults with low muscle strength. …”
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Circular RNAs: key regulators of paclitaxel sensitivity and resistance in cancer
Published 2025-08-01“…We highlight two major pathways—miRNA sponging and protein interactions—through which circRNAs alter drug sensitivity. …”
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Gastric juice MicroRNAs as biomarkers for functional dyspepsia: an observational case-control study
Published 2025-08-01“…These miRNA alterations align with the symptomatology of FD subtypes and may reflect underlying pathophysiological differences. …”
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Decoding the diagnostic biomarkers of mitochondrial dysfunction related gene variants in pediatric T cell acute lymphoblastic leukemia
Published 2025-07-01“…Additionally, A mitochondrial dysfunction-based signature was created to predict pediatric T-ALL. The mRNA-miRNA and mRNA-TF Regulatory Network were constructed, and the molecular distributions of key genes were calculated. …”
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