Clinical Characteristics and Risk Factors for Multidrug-Resistant Enterobacter cloacae Complex Bacteremia in a Chinese Tertiary Hospital: A Decade Review (2013–2022) by Han M, Hua M, Xie H, Li J, Wang Y, Shen H, Cao X

“…Mei Han,1,2,* Miaomiao Hua,3,* Hui Xie,1 Jia Li,1 Yijun Wang,2,4 Han Shen,1 Xiaoli Cao1 1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, People’s Republic of China; 2Nanjing Field Epidemiology Training Program, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, Jiangsu, People’s Republic of China; 3Department of Laboratory Medicine, The Affiliated Fuyang Hospital of Anhui Medical University, Fuyang, Anhui, People’s Republic of China; 4Nanjing Jiangning District Center for Disease Control and Prevention, Nanjing, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaoli Cao; Han Shen, Email cao-xiao-li@163.com; shenhan10366@sina.comObjective: This study aimed to analyze the antimicrobial resistance profiles, clinical characteristics and risk factors of bacteremia caused by Enterobacter cloacae complex (ECC) strains.Methods: We retrospectively collected clinical data from patients diagnosed with ECC bacteremia between 2013 and 2022 in a tertiary hospital in Jiangsu. …”
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Leucocytosis and Asymptomatic Urinary Tract Infections in Sickle Cell Patients at a Tertiary Hospital in Zambia by Taonga Musonda, Mildred Zulu, Mulemba Samutela, Annie Kalonda, Hamakwa Mantina, Pauline Okuku, Musalula Sinkala, Panji Nkhoma

“…There was a high prevalence of asymptomatic UTIs among SCA patients at UTH, which, when coupled with the marked leukocytosis and anaemia, may negatively impact the clinical outcome of the patients. …”
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Closing the gap while standing still: clinimetric properties of a low-cost balance platform and a user-friendly app for posturography by Tom Vredeveld, John F. Stins, Annelies J. van Vliet, Vincent C.M. Tuinder, Stephan P.J. Ramaekers, Michel W. Coppieters, Annelies L. Pool-Goudzwaard

“…Methods A cross-sectional study was carried out including 30 healthy adults who performed repeated balance tasks including single and double leg standing still with eyes open or eyes closed. …”
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Carbon cycle and climate feedbacks under CO₂ and non-CO₂ overshoot pathways by I. Melnikova, I. Melnikova, P. Ciais, K. Tanaka, K. Tanaka, H. Shiogama, K. Tachiiri, K. Tachiiri, T. Yokohata, O. Boucher

“…This study investigates the impact of <span class="inline-formula">CO₂</span> and non-<span class="inline-formula">CO₂</span> gases with nearly equal levels of effective radiative forcing on the climate and carbon cycle, using the Earth system model (ESM) IPSL-CM6A-LR. …”
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Molecular Docking Appraisal of Phytochemicals as Potential Inhibitors of PI3K/Akt Pathway for Breast Cancer Treatment by Magdalene Eno Effiong, Mercy Bella-Omunagbe, Israel Sunmola Afolabi, Shalom Nwodo Chinedu

“…Phosphoinositide 3-kinase, phosphatase and tensin homolog (PTEN), mTOR, Akt, 3-phosphoinositide-dependent kinase 1 (PDK1), FoxO1, glycogen synthase kinase 3 (GSK-3), mouse double minute 2 (MDM2), H-Ras, and proapoptotic B-cell lymphoma 2 (BCL-2) family protein (BAD) proteins are key drivers of this pathway and potential therapeutic targets. …”
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METHODICAL APPROACH TO THE DETERMINATION OF THE ANTIOXIDANT ACTIVITY OF THE ECHINACEA PURPUREA AND MONARDA FISTULOSA TINCTURES AS A QUALITY CRITERION OF THE DEVELOPMENT OF THEIR CO... by Oksana Yezerska, Nataliia Hudz, Lesya Kobylinska, Anna Filipska, Vira Turkina, Jan Brindza, Piotr Pawel Wieczorek

“…The antioxidant activity of the tinctures of the Monarda fistulosa herb was equal to 2203.6 mg eq-rutin/L and 20.3 mg eq-rutin/g for the tincture and HRM at a ratio of 1 to 9.5 and 2119.4 mg eq-rutin/L and 9.7 mg eq-rutin/g for the tincture at a ratio of 1 to 4.5. …”
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Design and validation of a-SiC/SiN hybrid photonic platform for integrated quantum photonics by Naresh Sharma, Zizheng Li, Bruno Lopez-Rodriguez, Joey Vrugt, Stijn van der Waal, Luozhen Li, Roald van der Kolk, Philip J Poole, Dan Dalacu, Iman Esmaeil Zadeh

“…Furthermore, we design and simulate an adiabatic coupler between two photonic platforms, a-SiC and SiN, by aiming to use the benefits of both platforms, i.e. dense integration and low losses, respectively. Our design couples the light from SiN waveguide to a-SiC waveguide with 96% efficiency at 885 nm wavelength. …”
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Effects of Food on the Pharmacokinetics and Safety of HA121-28 Tablet, a Novel Multi-Targeting Tyrosine Kinase Inhibitor, in Healthy Chinese Subjects: A Phase I Clinical Trial by Liu Y, Li X, Zhang M, Men Y, Wang Y, Zhu X, Zheng L

“…Yixian Liu,1,2,&ast; Xiaoyu Li,1,2,&ast; Mengyu Zhang,1,2 Yuchun Men,1,2 Ying Wang,1,2 Xiaohong Zhu,1,2 Li Zheng1,2 1Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China; 2Clinical Trial Center, NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Li Zheng, Cancer Center, West China Hospital, Sichuan University, No. 5 Telecom Road, Wuhou District, Chengdu, 610041, People’s Republic of China, Email zhengli@wchscu.cnPurpose: HA121-28, a novel multi-targeting tyrosine kinase inhibitor, has dual efficacy against tumor growth and neovascularization. …”
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Prediction and Impact of Supersaturated Total Dissolved Gas in Flood Discharge of Flood Control Reservoirs in Southwest Mountain Areas: A Case Study in Jiangjiakou Reservoir by ZHANG Zhihao, ZHANG Peng, LIANG Ruifeng, WANG Qingfeng, WANG Yuanming, LI Kefeng

Subjects: “…total dissolved gas…”
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Influence of Coal Caving Time and Tail Beam Swing Angle on the Evolution of the Coal Gangue Boundary Line during Top Coal Caving by Qingliang Zeng, Yanpeng Zhu, Yang Yang, Zhe Li, Lirong Wan

“…After the end of coal caving, the coal gangue boundary finally presents a double arch structure. …”
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Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects by Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama

“…In the efficacy study, a randomized, double-blinded, and placebo-controlled crossover trial, the effects of 3-HB at the predicted doses on cognitive function and mood in healthy subjects were assessed by a serial arithmetic test (SAT), the cognitrax, the profile of mood states 2nd edition (POMS2), and fatigue visual analog scale (VAS).ResultsIn the pharmacokinetic study, a one-compartment model that includes saturable and non-saturable absorption pathways, constant biosynthesis, and the linear elimination of 3-HB after oral administration were constructed. …”
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Magnitude and Factors Associated with Precervical Cancer among Screened Women in Southern Ethiopia by Terefu Teka, Mesfin Kote, Gemechu Kejela, Tagel Getachew

“…Data of 528 screened clients were entered into Epi data version 3.1 using checklist, double data entry verification done and exported to SPSS version 20.0. …”
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Direct antiglobulin test for the prediction of neonatal hyperbilirubinemia needing an intervention: a systematic review and diagnostic test accuracy meta-analysis by Vijay Kumar Krishnegowda, Viraraghavan Vadakkencherry Ramaswamy, Thangaraj Abiramalatha, Thangaraj Abiramalatha, Tapas Bandyopadhyay, Abdul Kareem Pullattayil S, Prakash Kannan Loganathan, Prakash Kannan Loganathan, Prakash Kannan Loganathan

“…However, evidence for this approach is limited.ObjectiveThe aim of this study was to evaluate the diagnostic utility of DAT in predicting the need for phototherapy and double volume exchange transfusion (DVET) in neonates with ABO and Rhesus (Rh) incompatibility conditions.MethodsMEDLINE, Embase, CENTRAL, CINAHL, and Web of Science were searched from inception until 1 February 2024. …”
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Fetal Spinal Cord Tissue in Mini-Guidance Channels Promotes Longitudinal Axonal Growth after Grafting into Hemisected Adult Rat Spinal Cords by Norman I. Bamber, Huaying Li, Patrick Aebischer, Xiao Ming Xu

“…Immunofluorescence results indicated that numerous neurofilament-positive axons were present within the FSC tissue cable. Double-labeling of a subpopulation of these axons with calcitonin generelated peptide indicated their peripheral nervous system (PNS) origin. …”
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Placental trophoblast aging in advanced maternal age is related to increased oxidative damage and decreased YAP by Song Guo, Song Guo, Qihao Pan, Qihao Pan, Baokang Chen, Baokang Chen, Yijuan Huang, Yijuan Huang, Si Li, Si Li, Chenyu Gou, Chenyu Gou, Yu Gao, Yu Gao

“…YAP expression in HTR8/SVneo cells was manipulated to investigate its role in trophoblastic senescence and oxidative damage.ResultsCompared with the control group, the AMA placenta exhibits increased aging biomarkers, which is coupled with an elevation in oxidative damage within placental trophoblast cells and a notable decline in YAP levels. …”
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Acceptability and efficacy of the culturally adapted problem management plus intervention for people with disability in Pakistan: a pilot cluster randomized controlled trial by Basharat Hussain, Basharat Hussain, Muhammad Tahir Khalily, Muhammad Tahir Khalily, Ahmed Waqas, Atif Rahman, Ioannis Angelakis, Anum Nisar, Sabir Zaman, Tanveer Akhtar

“…It compared an Active Treatment group, receiving five sessions of the IA-PM+ intervention, against a Delayed Treatment Control group. A total of 148 participants were randomized. Randomization occurred at the village level, with clusters assigned to either the intervention or control group. …”
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Characterization of Pancreatic Infections in Patients with Severe Acute Pancreatitis: A Retrospective Study from 2019 to 2023 by Chen Y, Cui Q, Cao J, Wu Q, Lu P, Li G, Sun N

“…Multivariable logistic regression was used to evaluate the association between multidrug-resistant organism (MDRO) infection and poor prognosis.Results: A total of 1586 pancreatic fluid specimens were analyzed and collected from 843 patients diagnosed with AP. …”
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Clinical Study of MOTOmed Intelligent Training System Combined with Weight Support Gait Training on Improving Hemiplegic Gait of Stroke Patients with Hemiplegia by LI Na, LIANG Xueqin, PAN Fangfang, DUAN Yanan, ZHANG Xiangyu

“…Compared with the control group, after 4 weeks of treatment, the Barthel index score of the experimental group increased (<italic>P</italic>&lt;0.05), the percentage of single support period, step speed, step frequency and step length of the affected side increased, and the percentage of double support period decreased (<italic>P</italic>&lt;0.05). …”
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Hz. Peygamber’in Gazve ve Seriyyeleri’nde İâşe İkmâl Faaliyetleri by Serdar Sevmezler

“…Şahsi yiyecekler, devlet desteği, doğal kaynaklar, harp ganimetleri, satın alımlar, bağış ve yardımlar, antlaşmalar yoluyla tedarik ve avlanma yoluyla edinilenler temel iâşe tedarik kaynaklarını oluşturmaktaydı. …”
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La villégiature anglaise et l’invention de la Côte d’Azur by Alain Bottaro

“…The originality of Nice lies in the double influence of Italian and British models which are interwoven in local bathing practices and architecture.…”
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