Automated segmentation of brain metastases in T1-weighted contrast-enhanced MR images pre and post stereotactic radiosurgery by Hemalatha Kanakarajan, Wouter De Baene, Patrick Hanssens, Margriet Sitskoorn

“…Abstract Background and purpose Accurate segmentation of brain metastases on Magnetic Resonance Imaging (MRI) is tedious and time-consuming for radiologists that could be optimized with deep learning (DL). Previous studies assessed several DL algorithms focusing only on training and testing the models on the planning MRI only. …”
Get full text

The potential role of next-generation sequencing in identifying MET amplification and disclosing resistance mechanisms in NSCLC patients with osimertinib resistance by Xiao Xiao, Xiao Xiao, Ren Xu, Ren Xu, Jun Lu, Beibei Xin, Chenyang Wang, Kexin Zhu, Hao Zhang, Xinyu Chen

“…With FISH results as gold standard, enumeration algorithm was applied to establish the optimal model for identifying MET amplification using gene copy number (GCN) data.ResultsThe optimal model for identifying MET amplification was constructed based on the GCN of MET, BRAF, CDK6 and CYP3A4, which achieved a 74.0% overall agreement with FISH and performed well in identifying MET amplification except polysomy with a sensitivity of 85.7% and a specificity of 93.9%. …”
Get full text

Electrophysiological changes in the acute phase after deep brain stimulation surgery by Lucia K. Feldmann, Diogo Coutinho Soriano, Jeroen Habets, Valentina D'Onofrio, Jonathan Kaplan, Varvara Mathiopoulou, Katharina Faust, Gerd-Helge Schneider, Doreen Gruber, Georg Ebersbach, Hayriye Cagnan, Andrea A. Kühn

“…Background: With the introduction of sensing-enabled deep brain stimulation devices, characterization of long-term biomarker dynamics is of growing importance for treatment optimization. The microlesion effect is a well-known phenomenon of transient clinical improvement in the acute post-operative phase. …”
Get full text

A comprehensive review of data analytics and storage methods in geothermal energy operations by Ali Basem, Ahmed Kateb Jumaah Al-Nussairi, Dana Mohammad Khidhir, Narinderjit Singh Sawaran Singh, Mohammadreza Baghoolizadeh, Mohammad Ali Fazilati, Soheil Salahshour, S. Mohammad Sajadi, Ali Mohammadi Hasanabad

“…The study also delves into the potential of machine learning to optimize geothermal design, monitor performance, improve performance, find errors, and more. …”
Get full text

Machine learning to predict virological failure among HIV patients on antiretroviral therapy in the University of Gondar Comprehensive and Specialized Hospital, in Amhara Region, E... by Daniel Niguse Mamo, Tesfahun Melese Yilma, Makda Fekadie Tewelgne, Yakub Sebastian, Tilahun Bizuayehu, Mequannent Sharew Melaku, Agmasie Damtew Walle

“…Thus, Machine learning predictive algorithms have the potential to improve the quality of care and predict the needs of HIV patients by analyzing huge amounts of data, and enhancing prediction capabilities. …”
Get full text

Early Warning of Axillary Lymph Node Metastasis in Breast Cancer Patients Using Multi-Omics Signature: A Machine Learning-Based Retrospective Study by Ke Z, Shen L, Shao J

“…The AUC of GLRM was 0.818 (95% CI: 0.757~0.879), significantly lower than that of RFM’s AUC 0.893 (95% CI: 0.836~0.950).Conclusion: The prediction models based on machine learning (ML) algorithms and multiomics have shown good performance in predicting ALN metastasis, and RFM shows greater advantages compared to traditional GLRM. …”
Get full text

Histopathological Image Analysis Using Machine Learning to Evaluate Cisplatin and Exosome Effects on Ovarian Tissue in Cancer Patients by Tuğba Şentürk, Fatma Latifoğlu, Çiğdem Gülüzar Altıntop, Arzu Yay, Zeynep Burçin Gönen, Gözde Özge Önder, Özge Cengiz Mat, Yusuf Özkul

“…Further research is warranted to validate these findings and optimize treatment protocols.…”
Get full text

Research on High Arch Dam Deformation Monitoring Model with Deep Capturing Related Features in Factor-time Dimensions by XUE Jianghan, ZHANG Pengtao, TIAN Jichen, LU Xiang, CHEN Jiankang, Guo Yinju

“…However, at the present stage, the dam prediction model based on machine learning mostly adopts the means of data preprocessing, using optimization algorithm, and using the model's characteristics to stack multiple models, lacking in in-depth consideration of the physical mechanism of dam deformation. …”
Get full text

Machine learning for detection of diffusion abnormalities-related respiratory changes among normal, overweight, and obese individuals based on BMI and pulmonary ventilation paramet... by Xin-Yue Song, Xin-Peng Xie, Wen-Jing Xu, Yu-Jia Cao, Bin-Miao Liang

“…We evaluated the effectiveness of various supervised ML algorithms and identified the optimal configurations for these applications. …”
Get full text

HOW I TREAT PH+ ACUTE LYMPHOBLASTIC LEUKEMIA by Robin Foà

“…I have been asked to cover ‘How I Treat Ph+ALL’, which more appropriately should be ‘How Should I Treat Ph+ LL’ Based on the 25-year experience gathered through the GIMEMA trials, the optimal algorithm should be: i) Identify the presence of the BCR/ABL gene lesion within one week from diagnosis; ii) During this time treat patients with steroids; iii) Start induction with dasatinib or ponatinib plus steroids, with no systemic chemotherapy; iv) CNS prophylaxis should be carried out; v) MRD should be monitored molecularly at given timepoints; vi) After induction, all patients should be consolidated with multiple cycles of blinatumomab (up to 5 in our protocols); vii) TKI should not be stopped. …”
Get full text

Approaches to Extracting Patterns of Service Utilization for Patients with Complex Conditions: Graph Community Detection vs. Natural Language Processing Clustering by Jonas Bambi, Hanieh Sadri, Ken Moselle, Ernie Chang, Yudi Santoso, Joseph Howie, Abraham Rudnick, Lloyd T. Elliott, Alex Kuo

“…Once extracted, PSUs can provide quality assurance/quality improvement (QA/QI) efforts with the information required to optimize service system structures and functions. …”
Get full text

A Distributed Collaborative Navigation Strategy Based on Adaptive Extended Kalman Filter Integrated Positioning and Model Predictive Control for Global Navigation Satellite System/... by Wanqiang Chen, Yunpeng Jing, Shuo Zhao, Lei Yan, Quancheng Liu, Zichang He

“…This framework predicts and optimizes each robot’s kinematic model, thereby improving the system’s collaborative operations and dynamic decision-making capabilities. …”
Get full text

Diabetes mellitus in the Russian Federation: dynamics of epidemiological indicators according to the Federal Register of Diabetes Mellitus for the period 2010–2022 by I. I. Dedov, M. V. Shestakova, O. K. Vikulova, A. V. Zheleznyakova, M. A. Isakov, D. V. Sazonova, N. G. Mokrysheva

“…The information-analytical system FDR is a key tool for systematizing the most important epidemiological and clinical characteristics of DM based on data from real clinical practice, which allows optimizing the algorithm of patient management and improving the quality of care for diabetes.…”
Get full text

Beyond the current state of just-in-time adaptive interventions in mental health: a qualitative systematic review by Claire R. van Genugten, Claire R. van Genugten, Melissa S. Y. Thong, Melissa S. Y. Thong, Melissa S. Y. Thong, Wouter van Ballegooijen, Wouter van Ballegooijen, Wouter van Ballegooijen, Annet M. Kleiboer, Annet M. Kleiboer, Donna Spruijt-Metz, Arnout C. Smit, Mirjam A. G. Sprangers, Mirjam A. G. Sprangers, Yannik Terhorst, Yannik Terhorst, Heleen Riper, Heleen Riper, Heleen Riper

“…Regarding the current state of studies, initial findings on usability, feasibility, and effectiveness appear positive.ConclusionsJITAIs for mental health are still in their early stages of development, with opportunities for improvement in both development and testing. For future development, it is recommended that developers utilize complex analytical techniques that can handle real-or near-time data such as machine learning, passive monitoring, and conduct further research into empirical-based decision rules and points for optimization in terms of enhanced effectiveness and user-engagement.…”
Get full text

A Clinically Interpretable Approach for Early Detection of Autism Using Machine Learning With Explainable AI by Oishi Jyoti, Hafsa Binte Kibria, Zareen Tasnim Pear, Md Nahiduzzaman, Md. Faysal Ahamed, Khandaker Reajul Islam, Jaya Kumar, Muhammad E. H. Chowdhury

“…SHAP are also illustrated to improve model interpretability by highlighting the most influential features, thereby aiding physician understanding. …”
Get full text

Exploration of heterogeneity of treatment effects across exercise-based interventions for knee osteoarthritis by Paul A. Dennis, Livia Anderson, Cynthia J. Coffman, Sara Webb, Kelli D. Allen

“…Objective: Variability exists in the degree of improvement patients experience following exercise-based interventions (EBIs) for knee osteoarthritis (KOA), but understanding of this heterogeneity is limited. …”
Get full text

Machine Learning-Driven Prediction of One-Year Readmission in HFrEF Patients: The Key Role of Inflammation by Ma F, Hu Y, Han P, Qiu Y, Liu Y, Ren J

“…SHAP analysis showed that BNP was the most influential feature, followed by NYHA class and LVEF, which were also important predictors. …”
Get full text

Real-time mobile broadband quality of service prediction using AI-driven customer-centric approach by Ayokunle A. Akinlabi, Folasade M. Dahunsi, Jide J. Popoola, Lawrence B. Okegbemi

“…Three (3) classification algorithms including Random Forest (RF), Support Vector Machine (SVM) and Extreme Gradient Boosting (XGBoost) were trained using the QoS dataset and then evaluated in order to determine the most effective model based on certain evaluation metrics – accuracy, precision, F1-Score and recall. …”
Get full text

Breast lesion classification via colorized mammograms and transfer learning in a novel CAD framework by Abbas Ali Hussein, Morteza Valizadeh, Mehdi Chehel Amirani, Sedighe Mirbolouk

“…A variety of techniques are implemented in the pre-processing section to minimize noise and improve image perception; however, the most challenging methodology is the application of creative techniques to adjust pixels’ intensity values in mammography images using a data-driven transfer function derived from tumor intensity histograms. …”
Get full text

Predicting Pathological Complete Response Following Neoadjuvant Therapy in Patients With Breast Cancer: Development of Machine Learning–Based Prediction Models in a Retrospective S... by Chun-Chi Lai, Cheng-Yu Chen, Tzu-Hao Chang

“…The application of logistic regression with recursive feature elimination with cross-validation was found to demonstrate the optimal performance among the various algorithms that were evaluated in this study. …”
Get full text