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481
Investigation of the role of afterhyperpolarizaÜon potential in the formation of the electrical signals in some brain cells of mouse, rat and helix aspersa
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482
Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism
Published 2025-01-01“…Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in the parkinsonian condition.ObjectiveInvestigate the impact of parkinsonism on neuronal activity in the dorsolateral prefrontal cortex (DLPFC), a key region in executive control, during a go/nogo reaching task.MethodsUsing a within-subject design, single and multi-unit neuronal activity was recorded in the DLPFC of a nonhuman primate (n = 1) before and after the induction of mild parkinsonism using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).ResultsCoincident with development of mild parkinsonian motor signs, there was a marked reduction in the percentage of DLPFC cells with significant task-related firing rate modulation during go and nogo conditions.ConclusionThese results suggest that DLPFC dysfunction may occur early in parkinsonism and contribute to cognitive impairments and disrupted executive function often observed in PD patients.…”
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483
Electrophysiologically calibrated optogenetic stimulation of dentate granule cells mitigates dendritic spine loss in denervated organotypic entorhino-hippocampal slice cultures
Published 2025-02-01“…Denervated GCs exhibited significant spine loss four days post-denervation, but this detrimental effect was mitigated when AP firing was induced at a physiological GC bursting rate. …”
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484
Impactos atmosféricos das transformações territoriais e do crescimento do agronegócio na Amazônia matogrossense
Published 2010-11-01“…Then, there is little doubt that agribusiness can be regarded as one of the drivers of the increase in biomass burning fires in this State, where a record peak was so far document in September 2004 with almost 25000 occurrences – 35% of all fires detected in Brazil in the same month. …”
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485
Evaluation the Effect of different Cooling Cycles on the Hardness Surface of the Conventional Feldspathic Zirconia
Published 2021-09-01“…Fast cooling group: these specimens were fast cooled after second firing (910C0 -600C0) with opening Oven muffle 25% withholding time for 5 minute and remove from the furnace to cool at room temperature. …”
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486
One in a Million: A Case Report of Stiff Person Syndrome
Published 2022-01-01“…Stiff person syndrome (SPS) is a rare autoimmune disease caused by lack of inhibition to excitatory neurotransmitters in the central nervous system (CNS) leading to inappropriate motor unit firing. The pathophysiology is incompletely understood; however, high titers of antiglutamic acid decarboxylase antibody (anti-GAD Ab) are strongly associated with this disease. …”
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487
Dopaminergic modulation of propofol-induced activation in VLPO neurons: the role of D1 receptors in sleep-promoting neural circuits
Published 2025-01-01“…We assessed the effects of PRO on spontaneous excitatory postsynaptic currents (sEPSCs) and inhibitory postsynaptic currents (sIPSCs) in NA (−) neurons, both in the presence and absence of dopaminergic receptor modulators.ResultsPRO significantly increased the firing frequency of NA (−) neurons while decreasing the firing frequency of NA (+) neurons. …”
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488
Distribution and Fate of Military Explosives and Propellants in Soil: A Review
Published 2012-01-01“…This paper addresses the occurrence of energetic materials in soils including a discussion of their fates after contact with soil. …”
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489
Presynaptic Ionotropic Receptors Controlling and Modulating the Rules for Spike Timing-Dependent Plasticity
Published 2011-01-01“…In addition, timing rules for STDP within synapses are not fixed. They can be altered by activation of ionotropic receptors located at, or close to, synapses. …”
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490
Empowering Aid Personnel That Respond to Disasters
Published 2021-07-01“…Accordingly, the literature on the effects of natural or man-made disasters on victims and communities is abundant. …”
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491
Probing Neural Transplant Networks In Vivo with Optogenetics and Optogenetic fMRI
Published 2016-01-01“…Understanding how stem cell-derived neurons functionally integrate into the brain upon transplantation has been a long sought-after goal of regenerative medicine. However, methodological limitations have stood as a barrier, preventing key insight into this fundamental problem. …”
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492
Quasi-Dimensional Modelling and Parametric Studies of a Heavy-Duty HCCI Engine
Published 2011-01-01“…This study shows that HCCI combustion mode can be employed at part load of 25% varying the EGR rates between 0 and 60%.…”
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493
Iran-Saudi Arabia Rivalry and the Yemen Crisis
Published 2022-12-01“…The Arab Spring process, on the other hand, made the Hobbesian anarchic structure among the Middle Eastern states even more evident. In this respect, after the Arab Spring, an axis of tension has emerged between Iran and Saudi Arabia, covering countries such as Yemen, Syria, Lebanon, Iraq and Bahrain. …”
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494
La prison de Guingamp, de l’ombre à la lumière
Published 2024-01-01“…Without any maintenance, it deteriorated heavily, victim of storms and fires. Purchased in 1992 by the municipality of Guingamp, then listed in the supplementary inventory of historical monuments, the process led to the classification of the former prison and its walls in 1997. …”
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495
Approvisionner les villes en briques et en tuiles : les carrières urbaines d’argile en France
Published 2022-12-01“…The case of Beauvais shows that the extraction and firing of clay contributed to the construction of a peri-urban area.…”
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496
Integrated DEA Models and Grey System Theory to Evaluate Past-to-Future Performance: A Case of Indian Electricity Industry
Published 2015-01-01“…Totally, the realistic data 14 are considered to be in this evaluation after the strict selection from the whole industry. …”
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497
Investigation of the gas-solid and Fuel-N conversion characteristics during pulverized coal preheating with an improved char model
Published 2025-01-01“…Nitrogen oxides (NOx) emissions will exceed the limit when a coal-fired boiler is operated at low load. Preheating is an economically viable technology for reducing NOx emissions. …”
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498
Functional Change in the Caudal Pontine Reticular Nucleus Induced by Age-Related Hearing Loss
Published 2018-01-01“…In this study, the local field potentials and firing rates of the caudal pontine reticular nucleus (PnC), which plays a major role in the ASR pathway, were recorded in 2-month- and 6-month-old C57BL/6 J mice. …”
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499
The Influence of Cochlear Implant-Based Electric Stimulation on the Electrophysiological Characteristics of Cultured Spiral Ganglion Neurons
Published 2020-01-01“…Cochlear implant-based electrical stimulation may be an important reason to induce the residual hearing loss after cochlear implantation. In our previous study, we found that charge-balanced biphasic electrical stimulation inhibited the neurite growth of spiral ganglion neurons (SGNs) and decreased Schwann cell density in vitro. …”
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500
Impact of bottom ash addition on Pleurotus ostreatus cultivation on coffee ground substrate
Published 2024-12-01“…Abstract The study aimed to explore the potential use of coal-fired power plant bottom ashes in Pleurotus ostreatus cultivation using spent coffee grounds. …”
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