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  1. 481
  2. 482

    Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism by Noah Hjelle, Biswaranjan Mohanty, Tanner Hubbard, Matthew D. Johnson, Jing Wang, Luke A. Johnson, Jerrold L. Vitek

    Published 2025-01-01
    “…Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in the parkinsonian condition.ObjectiveInvestigate the impact of parkinsonism on neuronal activity in the dorsolateral prefrontal cortex (DLPFC), a key region in executive control, during a go/nogo reaching task.MethodsUsing a within-subject design, single and multi-unit neuronal activity was recorded in the DLPFC of a nonhuman primate (n = 1) before and after the induction of mild parkinsonism using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).ResultsCoincident with development of mild parkinsonian motor signs, there was a marked reduction in the percentage of DLPFC cells with significant task-related firing rate modulation during go and nogo conditions.ConclusionThese results suggest that DLPFC dysfunction may occur early in parkinsonism and contribute to cognitive impairments and disrupted executive function often observed in PD patients.…”
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  3. 483

    Electrophysiologically calibrated optogenetic stimulation of dentate granule cells mitigates dendritic spine loss in denervated organotypic entorhino-hippocampal slice cultures by Tijana Hanauske, Carolin Christina Koretz, Tassilo Jungenitz, Jochen Roeper, Alexander Drakew, Thomas Deller

    Published 2025-02-01
    “…Denervated GCs exhibited significant spine loss four days post-denervation, but this detrimental effect was mitigated when AP firing was induced at a physiological GC bursting rate. …”
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  4. 484

    Impactos atmosféricos das transformações territoriais e do crescimento do agronegócio na Amazônia matogrossense by Andrea Cavicchioli, Ericka Pardini Morrone, Rodrigo Marques, Adalgiza Fornaro

    Published 2010-11-01
    “…Then, there is little doubt that agribusiness can be regarded as one of the drivers of the increase in biomass burning fires in this State, where a record peak was so far document in September 2004 with almost 25000 occurrences – 35% of all fires detected in Brazil in the same month. …”
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  5. 485

    Evaluation the Effect of different Cooling Cycles on the Hardness Surface of the Conventional Feldspathic Zirconia by Shahad Hazim Ali, Lateef Essa Alwan, Abdul Kareem J. Al-Azzawi

    Published 2021-09-01
    “…Fast cooling group: these specimens were fast cooled after second firing (910C0 -600C0) with opening Oven muffle 25% withholding time for 5 minute and remove from the furnace to cool at room temperature. …”
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  6. 486

    One in a Million: A Case Report of Stiff Person Syndrome by Ruchi Yadav, Neeraj Abrol, Sima Terebelo

    Published 2022-01-01
    “…Stiff person syndrome (SPS) is a rare autoimmune disease caused by lack of inhibition to excitatory neurotransmitters in the central nervous system (CNS) leading to inappropriate motor unit firing. The pathophysiology is incompletely understood; however, high titers of antiglutamic acid decarboxylase antibody (anti-GAD Ab) are strongly associated with this disease. …”
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  7. 487

    Dopaminergic modulation of propofol-induced activation in VLPO neurons: the role of D1 receptors in sleep-promoting neural circuits by Kun Qian, Kun Qian, Yu Zhang, Yang Liu, Sisi Wu, Zikun Duan, Jianhao Liao, Jianhao Liao, Wei Luo, Mo Zhou, Xuejiao Dou, Xingkui Liu, Tian Yu

    Published 2025-01-01
    “…We assessed the effects of PRO on spontaneous excitatory postsynaptic currents (sEPSCs) and inhibitory postsynaptic currents (sIPSCs) in NA (−) neurons, both in the presence and absence of dopaminergic receptor modulators.ResultsPRO significantly increased the firing frequency of NA (−) neurons while decreasing the firing frequency of NA (+) neurons. …”
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  8. 488

    Distribution and Fate of Military Explosives and Propellants in Soil: A Review by John Pichtel

    Published 2012-01-01
    “…This paper addresses the occurrence of energetic materials in soils including a discussion of their fates after contact with soil. …”
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  9. 489

    Presynaptic Ionotropic Receptors Controlling and Modulating the Rules for Spike Timing-Dependent Plasticity by Matthijs B. Verhoog, Huibert D. Mansvelder

    Published 2011-01-01
    “…In addition, timing rules for STDP within synapses are not fixed. They can be altered by activation of ionotropic receptors located at, or close to, synapses. …”
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  10. 490

    Empowering Aid Personnel That Respond to Disasters by Vedat Işıkhan

    Published 2021-07-01
    “…Accordingly, the literature on the effects of natural or man-made disasters on victims and communities is abundant. …”
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  11. 491

    Probing Neural Transplant Networks In Vivo with Optogenetics and Optogenetic fMRI by Andrew J. Weitz, Jin Hyung Lee

    Published 2016-01-01
    “…Understanding how stem cell-derived neurons functionally integrate into the brain upon transplantation has been a long sought-after goal of regenerative medicine. However, methodological limitations have stood as a barrier, preventing key insight into this fundamental problem. …”
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  12. 492

    Quasi-Dimensional Modelling and Parametric Studies of a Heavy-Duty HCCI Engine by Sunil Kumar Pandey, Muralitharan N., Ravikrishna R. V.

    Published 2011-01-01
    “…This study shows that HCCI combustion mode can be employed at part load of 25% varying the EGR rates between 0 and 60%.…”
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  13. 493

    Iran-Saudi Arabia Rivalry and the Yemen Crisis by Ramazan İZOL

    Published 2022-12-01
    “…The Arab Spring process, on the other hand, made the Hobbesian anarchic structure among the Middle Eastern states even more evident. In this respect, after the Arab Spring, an axis of tension has emerged between Iran and Saudi Arabia, covering countries such as Yemen, Syria, Lebanon, Iraq and Bahrain. …”
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  14. 494

    La prison de Guingamp, de l’ombre à la lumière by Emmanuel Laot

    Published 2024-01-01
    “…Without any maintenance, it deteriorated heavily, victim of storms and fires. Purchased in 1992 by the municipality of Guingamp, then listed in the supplementary inventory of historical monuments, the process led to the classification of the former prison and its walls in 1997. …”
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  15. 495

    Approvisionner les villes en briques et en tuiles : les carrières urbaines d’argile en France by Bruno Comentale

    Published 2022-12-01
    “…The case of Beauvais shows that the extraction and firing of clay contributed to the construction of a peri-urban area.…”
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  16. 496

    Integrated DEA Models and Grey System Theory to Evaluate Past-to-Future Performance: A Case of Indian Electricity Industry by Chia-Nan Wang, Nhu-Ty Nguyen, Thanh-Tuyen Tran

    Published 2015-01-01
    “…Totally, the realistic data 14 are considered to be in this evaluation after the strict selection from the whole industry. …”
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  17. 497

    Investigation of the gas-solid and Fuel-N conversion characteristics during pulverized coal preheating with an improved char model by Guojia Yao, Xiaoju Han, Hong Tang, Lingfang Sun, Guotao Liu

    Published 2025-01-01
    “…Nitrogen oxides (NOx) emissions will exceed the limit when a coal-fired boiler is operated at low load. Preheating is an economically viable technology for reducing NOx emissions. …”
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  18. 498

    Functional Change in the Caudal Pontine Reticular Nucleus Induced by Age-Related Hearing Loss by Ning Zhao, Ana’am Alkharabsheh, Fei Xu, Wei Sun

    Published 2018-01-01
    “…In this study, the local field potentials and firing rates of the caudal pontine reticular nucleus (PnC), which plays a major role in the ASR pathway, were recorded in 2-month- and 6-month-old C57BL/6 J mice. …”
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  19. 499

    The Influence of Cochlear Implant-Based Electric Stimulation on the Electrophysiological Characteristics of Cultured Spiral Ganglion Neurons by Na Shen, Lei Zhou, Bin Lai, Shufeng Li

    Published 2020-01-01
    “…Cochlear implant-based electrical stimulation may be an important reason to induce the residual hearing loss after cochlear implantation. In our previous study, we found that charge-balanced biphasic electrical stimulation inhibited the neurite growth of spiral ganglion neurons (SGNs) and decreased Schwann cell density in vitro. …”
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  20. 500

    Impact of bottom ash addition on Pleurotus ostreatus cultivation on coffee ground substrate by Anna Hnydiuk-Stefan, Jolanta Beata Królczyk, Dominika Barbara Matuszek, Łukasz Biłos, Żaneta Grzywacz, Marta Bożym, Robert Junga, Karol Bierczyński, Ritu Rai

    Published 2024-12-01
    “…Abstract The study aimed to explore the potential use of coal-fired power plant bottom ashes in Pleurotus ostreatus cultivation using spent coffee grounds. …”
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