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The integration of quantitative trait locus mapping and transcriptome studies reveals candidate genes for water stress response in St. Augustinegrass
Published 2025-05-01“…Breeding efforts have focused on breeding for drought resistance, and several drought-related quantitative trait loci (QTL) have been identified for St. …”
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Multi-dimensional annotation of porcine variants using genomic and epigenomic features in pigs
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Cross-tissue transcriptome-wide analysis reveals novel insights into thyroid cancer etiology
Published 2025-07-01“…Colocalization analysis further revealed that TGFB2 (rs1764705), SMAD3 (rs17293632), and SDCCAG8 (rs2490395) may share genetic signals between GWAS and expression quantitative trait loci (eQTL), indicating common pathways in TC pathogenesis. …”
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Mapping QTLs Affecting Economic Traits on BTA3 in Chinese Holstein with Microsatellite Markers
Published 2014-09-01“…It had been demonstrated that the strong and highly significant quantitative trait locus (QTL) can affect protein percentage on Bos Taurus Autosome 3 (BTA3) at the position 52 cM, near the microsatellite DIK4353, with the 95% confidence interval spanning from 25 to 57 cM in Chinese Holstein population using QTL-express, MQREML, and GRIDQTL softwares. …”
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Polymorphisms in cathepsin b is associated with growth in Asian seabass
Published 2025-09-01“…We analysed the full-length cDNA of ctsb and mapped it to the major quantitative trait locus (QTL) for growth on linkage group 2 in L. calcarifer. …”
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Deciphering antigen-specific T cell navigation tactics and cancer immune evasion in co-cultures
Published 2025-07-01“…Furthermore, post-interaction, a cancer-cell subpopulation displays immunosuppressive traits, reducing T cell attractant expression, and undergoing epithelial-to-mesenchymal transition. …”
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3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity
Published 2025-01-01“…Interestingly, this observation was also supported through colocalization analysis using expression quantitative trait loci (eQTL) derived from the Genotype-Tissue Expression (GTEx) dataset, supporting an inflammatory and neurologic component to the pathogenesis of childhood obesity. …”
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Deciphering the role of acetylation-related gene NAT10 in colon cancer progression and immune evasion: implications for overcoming drug resistance
Published 2025-05-01“…In the MR analysis, a significant positive correlation was observed between NAT10 and colorectal cancer risk using summary data from genome-wide association studies (GWAS) and expression quantitative trait loci (eQTL) studies (β_SMR = 0.004, p_SMR = 0.041, p_HEIDI = 0.737). …”
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Association studies for leaf rust resistance earmark differential genomic regions for silicon (Si) responsiveness in bread wheat (Triticum aestivum L.)
Published 2025-08-01“…A diverse wheat genotype panel, coupled with multi-year data, was utilized to perform genome-wide association studies (GWAS) to identify quantitative trait loci (QTLs) associated with Si response. …”
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