Inhibition of the anti-apoptotic protein BCL2 in EML4-ALK cell models as a second proposed therapeutic target for non-small cell lung cancer. by Richard Junior Zapata Dongo, Diletta Fontana, Luca Mologni, Juan Enrique Faya Castillo, Stefany Fiorella Infante Varillas

“…In addition, our analysis using bioinformatics indicated that ABT-199 not only targets BCL2 but also binds to the active site of all ALK mutants, it was contrasted by in vitro ALK kinase activity inhibition by ABT-199 (5.5 μM). …”
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Describing viewpoints on human‐nature relationships to unveil socio‐environmental conflicts and support community‐based projects by Beatriz Demasi, Nina Garcia de Almeida Prado, Flávia Pereira Lima, Charbel N. El‐Hani, Renata Pardini

“…Two viewpoints associated with community members revealed contrasting standpoints about nature resulting from complex transformations—from resource‐dependent to tourism‐dependent—in the community. …”
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Self-assessment of didactic performance of psychology and education professors in Mexico and Peru by Aldo Bazán-Ramírez, Walter Capa-Luque, Roberto Chávez-Nava, Mónica C. Dávila-Navarro, Homero Ango-Aguilar, Edmundo Hervias-Guerra, Catalina Bello-Vidal

“…The self-assessment of didactic performance is analyzed and the general didactic performance of the teacher and of his interactive episodes is contrasted according to some socio-academic characteristics. …”
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NEW ROLE FOR THE TEACHER: PREVENT STUDENTS FROM COMPLETELY ABANDONING THEMSELVES TO AI AND RELINQUISHING CONTROL OVER THEIR LEARNING. Illustration for foreign languages for specifi... by Felicia CONSTANTIN

“…This desire can be achieved by the responsible introduction of AI in the educational process, through contrastive comparison, which allows an almost cinematic viewing. …”
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American struggle for global leadership and the strategic options of Serbia by Lišanin Mladen

“…Contemporary turbulence regarding the issue of global leadership (referred to by some authors as "primacy" or "hegemony") takes place within a specific context, manifested through a single fundamental rift: the one based on key actors' attitudes towards the necessity of structural revision of the world system, contrasted with aspirations to maintain the status quo. …”
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Research on the Seismic Response Law of Complete Morphology of Butted Well Salt Cavern for Large-Scale Underground Energy Storage by Haitao Li, Dewen Zheng, Kang Li, Qiqi Wanyan, Lina Ran, Yanxia Kou, Song Bai, Jianan Wu, Jianchao Jia, Yunfei Wen, Yuanqing Wang, Hongyan Xing, Kuoyuan Zhu, Jingen Deng

“…The horizontal connection channel’s top and bottom surfaces exhibit contrasting reflection patterns, with the top position aligning with the reflection trough and the bottom reflection waveform shifting downward as the channel height increases. …”
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Mechanosensor YAP mediates bone remodeling via NF-κB p65 induced osteoclastogenesis during orthodontic tooth movement by Jie Deng, Yu-Ning Zhang, Ru-Shui Bai, Ting-Ting Yu, Yi Zhao, Hao Liu, Yun-Fan Zhang, Tian-Min Xu, Bing Han

“…Time-course analysis revealed two YAP activity peaks on day1 and 14, contrasting with one peak of type I collagen expression on day14. …”
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Exploring Score-Level and Decision-Level Fusion of Inertial and Video Data for Intake Gesture Detection by Hamid Heydarian, Marc T. P. Adam, Tracy L. Burrows, Megan E. Rollo

“…We first assess the potential of fusion by contrasting the performance of the individual models in intake gesture detection. …”
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Deciphering salt-responsive NB-ARC genes in rice transcriptomic data: A bioinformatics approach with gene expression validation by Saputro Triono Bagus, Wardhani Fila Oxi, Sholihah Nur Fadlilatus, Ermavitalini Dini, Purnama Putut Rakhmad, Nurhidayati Tutik

“…Two varieties with contrasting tolerance levels were selected for validation. …”
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Best organic farming expansion scenarios for pest control: a modeling approach by Delattre, Thomas, Memah, Mohamed-Mahmoud, Franck, Pierre, Valsesia, Pierre, Lavigne, Claire

“…We investigated the impact on pest density and on predator to pest ratio of three contrasted scenarios aiming at 50% organic fields through the progressive conversion of conventional fields. …”
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Qualitative analysis of patients’ feedback from a PROMs survey of cancer patients in England by Richard Wagland, Jessica Corner, Adam Glaser, Sir Mike Richards

“…Almost a fifth (19%) related experiences of excellent care during the treatment phase, with only 8% reporting negative experiences. This contrasted with experiences of care after primary cancer treatment where the majority were negative. …”
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Early childhood deprivation and the impact of negative life events on mental health in later life: a test of the stress sensitization hypothesis by Jala Rizeq, Mark Kennedy, Kirellos Miseih, Wangjingyi Liao, Edmund J. S. Sonuga-Barke

“…To test the specificity of these effects, we contrasted the effects on these outcomes with neuro-developmental problems (autism and disinhibited social engagement), known from previous studies to be associated with deprivation from early childhood.MethodsParticipants were 170 adoptees from the English and Romanian Adoptees study. …”
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Innate Immune Responses Associated with Resistance against Haemonchus contortus in Morada Nova Sheep by João Henrique Barbosa Toscano, Cintia Hiromi Okino, Isabella Barbosa dos Santos, Luciana Aparecida Giraldelo, Marei Borsch von Haehling, Sérgio Novita Esteves, Ana Carolina de Souza Chagas

“…The present study is aimed at evaluating mediators from the innate immune response in lambs of the Morada Nova Brazilian breed with contrasting H. contortus resistance phenotypes. Briefly, 287 lambs were characterized through fecal egg counts (FEC) and packed cell volume (PCV) after two independent experimental parasitic challenges with 4,000 H. contortus L3. 20 extreme resistance phenotypes (10 most resistant and 10 most susceptible) were selected, subjected to a third artificial infection with 4,000 L3, and euthanized 7 days later. …”
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Creep enhancement and sliding in a temperate, hard-bedded alpine glacier by J.-P. Roldán-Blasco, A. Gilbert, L. Piard, F. Gimbert, C. Vincent, O. Gagliardini, A. Togaibekov, A. Togaibekov, A. Walpersdorf, N. Maier

“…We suggest that these changes in deformation rate are due to variations in the stress field, driven by contrasting changes in subglacial hydrology conditions between the sides and center of the glacier. …”
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The good, the bad, and the ugly: Compliance of e-pharmacies serving India and Kenya with regulatory requirements and best practices. by Gautam Satheesh, Sammy Masibo, Sasi Kumar Tiruttani, Irene Khayoni, Benjamin Palafox, Devaki Nambiar, Jaison Joseph, Emmanuel Kweyu, Abdul Salam, Francis Wafula, Catherine Goodman

“…We developed and applied a checklist to assess compliance with best practices and regulations by e-pharmacies serving clients in India and Kenya, two countries with contrasting regulatory environments. We defined e-pharmacies as businesses selling prescription-only medicines directly to consumers through websites or apps. …”
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Distinct spatiotemporal patterns between fungal alpha and beta diversity of soil–plant continuum in rubber tree by Yaqing Wei, Zhixiang Wu, Guoyu Lan

“…Here, we explored the spatiotemporal dynamics of fungal communities across multiple compartments (phyllosphere, leaf endosphere, soil, rhizosphere, rhizoplane, and root endosphere) of rubber tree in two contrasting seasons collected from Hainan Island and Xishuangbanna. …”
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Revisiting Weimar Film Reviewers’ Sentiments: Integrating Lexicon-Based Sentiment Analysis with Large Language Models by Isadora Campregher Paiva, Josephine Diecke

“…Some of our early optimism was misplaced: while LLMs, and in particular ChatGPT, proved indeed to be much more adept at dealing with nuanced language, they are also difficult to control and implement in a consistent and reproducible way -- two things that lexicon-based sentiment analysis excels at. Given these contrasting sets of strengths and weaknesses, we propose an innovative solution which combines the two, and has more accurate results. …”
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ORGANICITY OF THE PHENOMENON OF CULTURE AS AN EXPLICATION OF VITALITY by D. B. Svyrydenko, O. D. Yatsenko, O. V. Prudnikova

“…The analysis performed standing from the point, that contrasting of nature and culture is irrelevant, since culture does not contradict natural determinants and patterns, but rather qualitatively alters them. …”
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Desenvolvimento do ensino remoto emergencial em uma instituição pública do ensino superior by Maria Denise Nunes Rodrigues, Iasmin Ribeiro Diniz, Mônica Carvalho Alves Cappelle

“… O ano 2020 teve uma realidade imposta e fora do controle da humanidade, tivemos que rever determinados comportamentos, bem como readequar a novos procedimentos, dentre estes, restrições quanto aos contatos sociais, de se manter em distanciamento social, tudo isso por conta de uma pandemia gerada pelo vírus COVID-19. …”
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Práticas da Coordenação Técnico-Pedagógica (COTP) do Instituto Federal de Educação, Ciência e Tecnologia do Rio de Janeiro: Ações para os Primeiros Passos do Ensino Remoto na EBTT... by Sílvia Cristina de Souza Trajano, João Vitor Juten

“…A metodologia adotada buscou transpor a experiência da CoTP com o ensino presencial, somada a atividades a distância, como um formado híbrido com apoio das tecnologias digitais e em especial o utilizando o recurso google meet nos primeiros contatos de mediação remota, partindo de temáticas de interesse discentes. …”
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