High-flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care: the FIRST-ABC RCTs by Padmanabhan Ramnarayan, Alvin Richards-Belle, Karen Thomas, Laura Drikite, Zia Sadique, Silvia Moler Zapata, Robert Darnell, Carly Au, Peter J Davis, Izabella Orzechowska, Julie Lester, Kevin Morris, Millie Parke, Mark Peters, Sam Peters, Michelle Saull, Lyvonne Tume, Richard G Feltbower, Richard Grieve, Paul R Mouncey, David Harrison, Kathryn Rowan

“…Continuous positive airway pressure Continuous positive airway pressure could be started using any approved medical device and patient interface at a set expiratory pressure of 7–8 cm H2O. To standardise treatment, clinical criteria and guidance for the initiation, maintenance and weaning of CPAP were provided in a trial algorithm. …”
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Novel magnetometer-free inertial-measurement-unit-based orientation estimation approach for measuring upper limb kinematics by Souha Baklouti, Taysir Rezgui, Abdelbadia Chaker, Anis Sahbani, Sami Bennour

“…Our proposed approach utilizes a Kalman-filter-based framework that analyzes the accelerometer’s alignment with the Earth’s frame to estimate orientation and correct gyroscope readings, eliminating reliance on magnetometer inputs. The algorithm was tested on both controlled robotic movements and real-world upper-limb-motion-monitoring scenarios. …”
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Maximizing Energy Efficiency in IRS-Assisted Phase Cooperative PS-SWIPT-Based Self-Sustainable IoT Network by Haleema Sadia, Ahmad Kamal Hassan, Ziaul Haq Abbas, Ghulam Abbas, Thar Baker, Nasir Saeed

“…The proposed solutions’ analysis shows low computational complexity and fast convergence, achieving near-optimal EE performance for different network settings. We conducted extensive simulations to evaluate our proposed framework’s performance and unveiled significant EE performance achieved by the IoT network consistent with the numerical findings. …”
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Compliance of cardiopulmonary resuscitation during in hospital cardiac arrest in a teaching institution by R. Arun Kumar, S. Chandresh, Ahamed Ashar Ali

“…Materials and Methods: Our study was conducted without randomization, blinding, or control groups, in all code blue victims aged between 20 and 80 years, who suffered cardiac arrest. …”
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Trust in Artificial Intelligence–Based Clinical Decision Support Systems Among Health Care Workers: Systematic Review by Hein Minn Tun, Hanif Abdul Rahman, Lin Naing, Owais Ahmed Malik

“…Studies in non–English languages and those unrelated to health care settings were excluded. Two independent reviewers followed the Cochrane Collaboration Handbook and PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 guidelines. …”
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Device-Driven Service Allocation in Mobile Edge Computing with Location Prediction by Qian Zeng, Xiaobo Li, Yixuan Chen, Minghao Yang, Xingbang Liu, Yuetian Liu, Shiwei Xiu

“…To validate the effectiveness of the proposed methods, we conduct multiple controlled experiments focusing on both location prediction models and service allocation algorithms. …”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…The system includes a combination of real-time continuous glucose monitoring from a continuous glucose monitoring device and a control algorithm to direct insulin delivery through an insulin pump. …”
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Comparative Study of Adaptive <i>l</i>₁-Regularization for the Application of Structural Damage Diagnosis Under Seismic Excitation by Weilin Wu, Junfang Wang, Jianfu Lin, Xuanyu Liu

“…These experimental investigations consider the influences of different parameter settings and uncertainties. Subsequently, the effects of damage patterns, available modal information, and solution algorithms are systematically analyzed and discussed. …”
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Remote, smart telemonitoring of COVID-19 survivors for early detection of deterioration in cardiac health (the PARTMO study) by Josephine Sau Fan Chow, Josephine Sau Fan Chow, Josephine Sau Fan Chow, Josephine Sau Fan Chow, Josephine Sau Fan Chow, Nutan Maurya, Nutan Maurya, Susan San Miguel, Rumbidzai Teramayi, Ahilan Parameswaran, Annamarie D’Souza, Gregory Melbourne, Joseph Descallar, Young Juhn, Enoch Chan, Jerome Pong

“…IntroductionThis study aims to implement a virtual model of care in the primary healthcare setting, utilising biosensor technologies (S-Patch EX) to remotely monitor and identify clinical signs and symptoms of cardiovascular conditions (mainly arrhythmias) in patients post-COVID-19 infection.MethodsThis open-label, non-randomised, observational study was conducted in patients aged 18 years and above, clinically diagnosed with COVID-19 after June 2021, and those residing within Greater Western Sydney. …”
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Assessing the causal effect of inflammation‐related genes on myocarditis: A Mendelian randomization study by Huazhen Xiao, Hongkui Chen, Wenjia Liang, Yucheng Liu, Kaiyang Lin, Yansong Guo

“…The GWAS data (finn‐b‐I9 MYOCARD) contained single nucleotide polymorphisms (SNPs) data from 117 755 myocarditis samples (16 379 455 SNPs, 829 cases vs. 116 926 controls). Five algorithms [MR‐Egger, weighted median, inverse variance weighted (IVW), simple mode, and weighted mode regression] were employed for the MR analysis, with IVW as the primary method, and sensitivity analysis was conducted. …”
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Development of Electronic Nose as a Complementary Screening Tool for Breath Testing in Colorectal Cancer by Chih-Dao Chen, Yong-Xiang Zheng, Heng-Fu Lin, Hsiao-Yu Yang

“…The objective of this study was to provide an assessment of the diagnostic performance of an electronic nose serving as a complementary screening tool to improve current screening programs in clinical settings. (2) Methods: We conducted a case–control study that included patients from a medical center with colorectal cancer and non-colorectal cancer controls. …”
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Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2) by Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Lucy Yardley, Beth Stuart, David A Turner, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Stephanie Hughes, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Gemma Mansell, Malcolm White, Firoza Davies, Paul Little

“…Setting Participants were recruited from 179 United Kingdom primary care practices. …”
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Delirium in tetanus patients: a review of clinical features, pathophysiology, and integrated management strategies by Yanwei Rao, Xinzao Xu, Lijing Chen, Di Wang, Lin Liu, Tingting Jiang, Yang Chen, Yongjie Wang

“…Introduction Tetanus remains a significant public health concern in resource-limited settings, with high mortality rates despite advances in critical care. …”
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A radiomics approach for predicting gait freezing in Parkinson’s disease based on resting-state functional magnetic resonance imaging indices: A cross-sectional study by Miaoran Guo, Hu Liu, Long Gao, Hongmei Yu, Yan Ren, Yingmei Li, Huaguang Yang, Chenghao Cao, Guoguang Fan

“…However, the effective integration of the multi-level indices of resting-state functional magnetic resonance imaging into clinical settings for the diagnosis of freezing of gait in Parkinson’s disease remains a challenge. …”
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Cervical cancer demystified: exploring epidemiology, risk factors, screening, treatment modalities, preventive measures, and the role of artificial intelligence by N. Mohammad, M. Khan, M. Maqsood, A. H. K. Naseeb

“…Material and Methods.A comprehensive literature review was conducted using peer-reviewed articles from Google Scholar, PubMed, and Scopus. …”
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CPAP management of COVID-19 respiratory failure: a first quantitative analysis from an inpatient service evaluation by Abdul Ashish, Alison Unsworth, Jane Martindale, Kanishka Kavuri, Luigi Sedda, Martin Farrier

“…Early clinical management with limited use of CPAP (3% of patients) was compared with a later clinical management strategy which had a higher proportion of CPAP use (15%).Design Retrospective case-controlled service evaluation for a single UK National Health Service (NHS) Trust during March–June 2020 designed and conducted solely to estimate the effects of current care.Setting The acute inpatient unit in Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust, a medium-sized English NHS Trust.Participants 206 patients with antigen confirmed COVID-19 disease and severe acute respiratory syndrome admitted between 17 March 2020 and 3 April 2020 for the early group (controls), and between 10 April 2020 and 11 May 2020 for the late group (cases). …”
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Security defense technology of power grid dispatching automation system based on hierarchical protection by ZHU Wen, HU Yaping, NIE Yongquan, JIANG Wei, XIE Hu

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Exploring the role of ferroptosis in pemphigus: identification of diagnostic markers and regulatory mechanisms by Jing Mao, Jianping Lan, Zheyu Zhuang, Ying Chen, Ying Chen, Yushan Ou, Xinhong Su, Xueting Zeng, Fuchen Huang, Zequn Tong, Xiaoqing Lv, Xiaoqing Lv, Xiaoqing Lv, Hui Ke, Zhenlan Wu, Ying Zou, Bo Cheng, Bo Cheng, Bo Cheng, Chao Ji, Chao Ji, Chao Ji, Ting Gong

“…Immune cell infiltration was assessed using CIBERSORT and single-sample Gene Set Enrichment Analysis (ssGSEA). Finally, experimental validation was conducted through real-time quantitative PCR, transmission electron microscopy, and drug prediction.ResultsOur results identified 1,840 DEGs in pemphigus patients compared to controls, with significant enrichment in pathways such as PI3K-Akt signaling and fatty acid metabolism. …”
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Geospatial impact evaluation of a low-cost agricultural intervention for enhancing environmental resilience by Pratap Khattri, Rachel Sayers, Kunwar K. Singh, Ryan Slapikas, Chet Bahadur Tamang, Dinee Tamang, Brad Sagara, Ariel BenYishay

“…However, while uptake was evident, the expected environmental outcomes, such as soil erosion control and riverbank stabilization, did not materialize. …”
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Deployment of real-time particle detection monitoring system in operating theatres for airborne contamination assessments: a methodological evaluation by Frans Stålfelt, Johan Tenghamn, Henrik Malchau, Karin Svensson Malchau

“…Advanced real-time monitoring technologies offer potential for improving infection control in surgical settings. This study evaluated real-time monitoring for airborne contamination; two scenarios were analyzed with the developed system: 1) the use of reusable non-disposable versus disposable surgical sheets; and 2) surgical team shift changes. …”
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