Aptamer Combined with Fluorescent Silica Nanoparticles for Detection of Hepatoma Cells by Zixi Hu, Juntao Tan, Zongqiang Lai, Rong Zheng, Jianhong Zhong, Yiwei Wang, Xiaoxue Li, Nuo Yang, Jieping Li, Wei Yang, Yong Huang, Yongxiang Zhao, Xiaoling Lu

“…SA-FSNPs showed no significant toxic effects in vitro or in vivo. Conclusion The combination of biotin-conjugated aptamers and SA-FSNPs shows promise for sensitive detection of hepatoma cells, and potentially of other tumor cell types as well.…”
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Nanofabricated Bacterial Cell Walls with Intrinsic Peroxidase‐Mimicking and Sonodynamic Activities for Cancer Combination Treatment by Meng Yang, Yang Meng, Junling Li, Liya Bai, Yuanyuan Cheng, Yuanyuan Liu, Mingxin Cao, Xiaoying Yang, Yinsong Wang, Yang Liu

“…Porphyromonas gingivalis (Pg), a Gram‐negative pathogenic bacterium, acquires protoporphyrin IX (PpIX) and iron from heme and synthesizes abundant µ‐oxo bisheme on its cell walls (CWs). For the first time, it is found that the CWs extracted from Pg has intrinsic peroxidase (POD)‐mimicking and sonodynamic activities owing to the presence of µ‐oxo bisheme. …”
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The use of T-cells with chimeric antigen receptor (CAR-T) in combination with chemotherapy and radiotherapy for the treatment of solid tumors by M. R. Khaliulin, R. N. Safin, M. A. Kunst, E. R. Bulatov

“…The effectiveness of combining chemotherapy and CAR-T cell therapy relies on various factors such as tumor type, dosage, treatment schedule, CAR-T cell composition, and individual biological traits. …”
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Emerging frontiers in cHCC-CCA organoid models: bridging stem cell innovation to precision oncology by Juntao Sun, Wenqing Liu, Ye Gao, Yuehuan Liu

Subjects: “…Adult stem cell…”
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The combination of paclitaxel and ipatasertib affects the death, proliferation, and autophagy response of oral squamous cell carcinoma cells by CHE Di, XU Pengkun, SONG Zhenyu, REN Baorui, GUAN Jian

“…[Results:] Both paclitaxel and ipatasertib alone and in combination promoted the death and proliferation of Cal-27 cells, and the combination resulted in higher cell lethality and inhibition than alone; both paclitaxel and ipatasertib alone and in combination enhanced autophagy in Cal-27 cells, and the combination was more effective than alone. …”
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SV-MeCa: an XGBoost-based meta-caller approach for structural variant calling from short-read data by Rudel Christian Nkouamedjo Fankep, Arda Söylev, Anna-Lena Kobiela, Jochen Blom, Corinna Ernst, Susanne Motameny

“…Therefore, meta-caller approaches combining the results of multiple standalone tools in a consensus set of reported SV calls, are widely used. …”
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Combination of nucleated red blood cells and inflammatory biomarkers (PCT and CRP) for predicting sepsis and septic shock in children by Kaibin Pu, Kaibin Pu, Kaibin Pu, Chunyi Wang, Jie Cheng, Jie Cheng, Jie Cheng, Dapeng Chen, Liping Tan, Liping Tan, Liping Tan, Jihong Tan, Jihong Tan, Jihong Tan, Hongdong Li, Hongdong Li, Hongdong Li

“…IntroductionSepsis remains a leading cause of mortality and morbidity worldwide. This study aimed to investigate the clinical characteristics of children with sepsis and septic shock, with emphasis to evaluate the predictive value of C-reactive protein (CRP), procalcitonin (PCT), and nucleated red blood cell (NRBC) count in pediatric sepsis and septic shock patients.MethodsWe included a total of 121 children, including 80 with sepsis and 41 with septic shock, who were admitted to the Children’s Hospital of Chongqing Medical University between January 2021 and June 2024.ResultsNo significant differences in sex, age, weight, or basic diseases were observed between the sepsis and septic shock groups (P > 0.05). …”
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Anticancer and Antiproliferative Effects of Combined Treatment with 5-Fluorouracil and Probiotic Lactobacillus Strains against Colorectal Cancer Cells by Sanaz Salek, Elham Moazamian, Afshin Mohammadi Bardbori Mohammadi Bardbori, Seyedeh Azra Shamsdin

“…Results: The results demonstrated the potential probiotic properties of all the studied Lactobacillus strains. The combination of cell extracts from Lactobacillus strains with 5-FU effectively reduced the viability of HT-29 cells.  …”
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The impact of maxillary anterior protraction combined with rapid arch expansion on buccal corridor and smile aesthetics in the treatment of skeletal Class Ⅲ malocclusion by ZHANG Rongxiu, XU Li, LIU Fang, TIAN Ruixue

“…Objective To explore the impact of maxillary anterior traction combined with rapidarch expansion on parabuccal space and smile aesthetics in patients with skeletal Class Ⅲ malocclusion. …”
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Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia by Qitao Chen, Yuqian Li, Qilin Zhu, Zhongming Li, Guanghui Shao, Yanjun Liu, Peixuan Jiang, Qiuwei Tao, Lili Shen, Jing Zhu, Linwei Wei, Yanhua Li, Xufeng Du

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Improving Segmentation of MRI Images of Brain Glial Cells Using Fuzzy C-Means Algorithm and Combination of PET Images by Wei Wang, Wu Beibei

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Gut microbiota and metabolic responses to a 12-week caloric restriction combined with strength and HIIT training in patients with obesity: a randomized trial by Libuša Nechalová, Viktor Bielik, Ivan Hric, Miriam Babicová, Eva Baranovičová, Marián Grendár, Juraj Koška, Adela Penesová

“…Twelve participants completed a 12-week program of caloric restriction combined with strength and HIIT training (INT, pre-BMI 37.33 ± 6.57 kg/m2), and eleven participants were designated as non-intervention controls (pre-BMI 38.65 ± 8.07 kg/m2). …”
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A comparative study of the effectivity of MSC-based, NP-based and combined therapies in an experimental model of NaIO3-induced retinal degeneration by Katerina Palacka, Barbora Hermankova, Tereza Cervena, Pavel Rossner, Vladimir Holan, Eliska Javorkova

“…Abstract Mesenchymal stem cells (MSCs) represent the promising options for retinal therapy and combined therapy with nanoparticles (NPs) could currently provide increased immunoregulatory and neuroprotective effects. …”
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Kidner Procedure: Alone or with Subtalar Arthroeresis for Symptomatic Accessory Navicular in Flexible Flatfoot—Is Combined Treatment Essential? by Thelma R. Jimenez Mosquea MD, Hugo A. Ubillus MD, Raymond J. Walls MD, FRCS (Orth), MFSEM, FAAOS

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Constraint-induced movement therapy combined with mesenchymal stem cell transplantation promotes myelination and functional recovery by inhibiting PRKCD/MEK/ERK pathway in hemiplegic cerebral palsy rats by Xiaolin Guo, Liru Liu, Jie Luo, Tingting Peng Jr., You Wang, Shiya Huang, Xiaoli Zeng, Tingting Peng Sr., Aihua Chen, Mengru Zhong, Yage Zhang, Kaishou Xu, Lu He

Subjects: “…Combination therapy…”
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Adrenocorticotropic hormone combined with vigabatrin as a second-line therapy for West syndrome by Luciana de Paula Souza, Danielle Caldas Bufara, Tallulah Spina Tensini, Sergio Antonio Antoniuk, Gustavo L. Franklin, Ana Chrystina de Souza Crippa

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Combination of αCD4 antibody and retinal antigen injection induces long-term disease control in autoimmune uveitis by Dijie Qiao, Lu Zhang, Yajie Zhong, Dongmei Liu, Zilin Chen, Wai Po Chong, Wai Po Chong, Wai Po Chong, Jun Chen

“…Flow cytometry was employed to analyze immune cell infiltration, and RNA sequencing of ocular tissue was performed to assess gene expression changes.ResultsMice receiving aCD4 antibody and IRBP1-20 showed sustained disease control up to 28 weeks, with reduced ocular inflammation, less retinal damage on OCT, and decreased immune cell infiltration compared to untreated controls. …”
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Predictive value and robustness of the stress hyperglycemia ratio combined with hypertension for stroke risk: evidence from the CHARLS cohort by Yaxuan He, Yu Cao, Rong Xiang, Fang Wang

“…Abstract Background Stroke remains a major cause of death and long-term disability worldwide, particularly in low- and middle-income countries. …”
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Flipped Classroom Combined With Group Awareness by Jian-Wei Lin, Hao-Chiang Koong Lin, Min‑Ling Hung

“…This study proposes a teaching model called “flipped classroom combined with group awareness” (FC+GA) to address the challenge of student preparedness in a traditional flipped classroom (FC) model setting. …”
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Tumor treating fields combined with ionizing radiation inhibit the malignant phenotype of lung cancer brain metastasis cells by suppressing DNA damage repair pathways by Guilong Tanzhu, Haiqin Peng, Liu Chen, Gang Xiao, Jiaoyang Ning, Ling Chen, Rongrong Zhou

“…Conclusions: TTFields combined with IR effectively inhibits LCBM cells. Mechanistically, this combined treatment enhanced DNA damage, suppressed DNA damage repair, and elevates ROS levels.…”
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