Showing 1 - 15 results of 15 for search 'bistable', query time: 0.04s Refine Results
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    MicroRNA governs bistable cell differentiation and lineage segregation via a noncanonical feedback by Chung‐Jung Li, Ee Shan Liau, Yi‐Han Lee, Yang‐Zhe Huang, Ziyi Liu, Andrew Willems, Victoria Garside, Edwina McGlinn, Jun‐An Chen, Tian Hong

    Published 2021-04-01
    “…Strikingly, we show that a wide range of biologically plausible post‐transcriptional regulatory parameters are sufficient to generate bistable switches, a hallmark of positive feedback. …”
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    Translational switch for long‐term maintenance of synaptic plasticity by Naveed Aslam, Yoshi Kubota, David Wells, Harel Z Shouval

    Published 2009-06-01
    “…Here, we examine the proposal that a self‐sustaining regulation of translation can form a bistable switch that can persistently regulate the on‐site synthesis of plasticity‐related proteins. …”
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    Deriving structure from evolution: metazoan segmentation by Paul François, Vincent Hakim, Eric D Siggia

    Published 2007-12-01
    “…The evolved state is a cell autonomous ‘clock and wavefront’ model, with the new attribute of a separate bistable system driven by an autonomous clock. Early stages in the evolution of both modes of segmentation are functionally similar, and simulations suggest a possible path for their interconversion. …”
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    Ultrasensitive gene regulation by positive feedback loops in nucleosome modification by Kim Sneppen, Mille A Micheelsen, Ian B Dodd

    Published 2008-04-01
    “…This mechanism can also generate bistable promoter responses, allowing a gene to be on in some cells and off in others, despite the cells being in identical conditions. …”
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    Dissection of a Krox20 positive feedback loop driving cell fate choices in hindbrain patterning by Yassine X Bouchoucha, Jürgen Reingruber, Charlotte Labalette, Michel A Wassef, Elodie Thierion, Carole Desmarquet‐Trin Dinh, David Holcman, Pascale Gilardi‐Hebenstreit, Patrick Charnay

    Published 2013-09-01
    “…We find that it underpins a bistable switch that turns a transient input signal into cell fate commitment, as we observe in single cell analyses. …”
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    A minimal deterministic model reveals integration of spindle assembly and position checkpoints in mitosis by Bashar Ibrahim

    Published 2025-07-01
    “…Notably, the model exhibits dual regulatory behavior: a bistable toggle switch within the SAC core driven by autocatalytic feedback, and a graded, rheostat-like output at the level of checkpoint satisfaction. …”
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    How Early Could the Milky Way’s Disk Form? by Vadim A. Semenov, Charlie Conroy, Aaron Smith, Ewald Puchwein, Lars Hernquist

    Published 2025-01-01
    “…In our enhanced-physics simulation, the galaxy develops a bistable ISM structure (warm, with T ∼ 10 ^4 K, and cold, with T < 100 K) and exhibits significantly more efficient, early, and bursty star formation than in TNG. …”
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    Hyperbaric Oxygen Therapy for PTSD: Threshold Effect for Sustained Symptom Improvement in a Biologically Based Treatment by Dor Danan, Yaniv Grosskopf, Avi Mayo, Shai Efrati, Ilan Kutz, Erez Lang, Uri Alon, Keren Doenyas‐Barak

    Published 2025-08-01
    “…The suggested underlying physiological mechanisms, involving bistable circuit dynamics, justify evaluating potential threshold effect in other treatment modalities. …”
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    Non-reciprocal frequency conversion in a non-Hermitian multimode nonlinear system by Sahil Pontula, Sachin Vaidya, Charles Roques-Carmes, Shiekh Zia Uddin, Marin Soljačić, Yannick Salamin

    Published 2025-08-01
    “…Abstract Nonlinear optics has become the workhorse for countless applications in classical and quantum optics, from optical bistability to single photon pair generation. However, the intrinsic weakness of optical nonlinearity and reciprocity of nonlinear interactions generally places stringent limits on the efficiency of nonlinear optical processes and their ability to be tailored for advanced applications in multimode systems. …”
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    Vegetation patterning can both impede and trigger critical transitions from savanna to grassland by Jelle van der Voort, Mara Baudena, Ehud Meron, Max Rietkerk, Arjen Doelman

    Published 2025-01-01
    “…Our model shows that these mechanisms lead to grass-tree coexistence and bistability between savanna and grassland states. Moreover, the model predicts vegetation patterns consisting of trees and grasses, particularly under harsh environmental conditions, which can persist in situations where a non-spatial version of the model predicts ecosystem collapse from savanna to grassland instead (a phenomenon called ‘Turing-evades-tipping’). …”
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