A comparative study of the developability of full-length antibodies, fragments, and bispecific formats reveals higher stability risks for engineered constructs by Itzel Condado-Morales, Fabian Dingfelder, Isabel Waibel, Oliver M. Turnbull, Bhargav Patel, Zheng Cao, Jais Rose Bjelke, Susanne Nedergaard Grell, Anja Bennet, Alissa M. Hummer, Matthew I. J. Raybould, Charlotte M. Deane, Thomas Egebjerg, Nikolai Lorenzen, Paolo Arosio

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Cellular EMT-status governs contact guidance in an electrospun TACS-mimicking in vitro model by Lorenz Isert, Mehak Passi, Benedikt Freystetter, Maximilian Grab, Andreas Roidl, Christoph Müller, Aditi Mehta, Harini G. Sundararaghavan, Stefan Zahler, Olivia M. Merkel

“…In this study, an advanced nanofiber breast cancer in vitro model was developed and systematically characterized including physico-chemical, cell-biological and biophysical parameters. …”
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Photodegradation of norfloxacin adsorbed on clay and carbon-clay nanomaterials: an evaluation based on antimicrobial tests by Zelaya-Soulé, María Emilia, Horue, Manuel, Torres Sánchez, Rosa María, Castro, Guillermo Raúl, Mártire, Daniel Osvaldo, Fernández, Mariela Alejandra, Arce, Valeria Beatriz

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The bronchoalveolar lavage fluid CD44 as a marker for pulmonary fibrosis in diffuse parenchymal lung diseases by Magda Suchankova, Magda Suchankova, Eszter Zsemlye, Eszter Zsemlye, Jan Urban, Peter Baráth, Lenka Kohútová, Barbara Siváková, Barbara Siváková, Martina Ganovska, Elena Tibenska, Kinga Szaboova, Eva Tedlova, Dominik Juskanic, Dominik Juskanic, Kristina Kluckova, Kristina Kluckova, Michaela Kardohelyova, Tetiana Moskalets, Anna Ohradanova-Repic, Patrik Babulic, Maria Bucova, Vladimir Leksa

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Mass‐Guided Single‐Cell MALDI Imaging of Low‐Mass Metabolites Reveals Cellular Activation Markers by James L. Cairns, Johanna Huber, Andrea Lewen, Jessica Jung, Stefan J. Maurer, Tobias Bausbacher, Stefan Schmidt, Pavel A. Levkin, Daniel Sevin, Kerstin Göpfrich, Philipp Koch, Oliver Kann, Carsten Hopf

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Development of antibacterial magnetic clay-based nanocomposites for water treatment by Horue, Manuel, Barraqué, Facundo, Montes, María Luciana, Zelaya-Soulé, María Emilia, Morantes, César Fernández, Urruchua, Florencia Camila, Correa, Hilda Edith, Castro, Guillermo Raul, Fernandez, Mariela Alejandra

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Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02 by Gwendolin S. Simper, Gia-Gia T. Hò, Alexander A. Celik, Trevor Huyton, Joachim Kuhn, Heike Kunze-Schumacher, Rainer Blasczyk, Christina Bade-Döding

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Bifurcation Analysis and Synchronous Patterns between Field Coupled Neurons with Time Delay by Li Zhang, Xinlei An, Jiangang Zhang, Qianqian Shi

“…From the perspective of biophysics, the activation of magnetic field coupling is the result of the continuous release and propagation of intracellular and extracellular ions, which is very similar to the activation of chemical synaptic coupling through the continuous release of neurotransmitters. …”
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Effects of nanocurcumin supplementation on metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials by Gofarana Wilar, Cecep Suhandi, Kohji Fukunaga, Masanori Shigeno, Ichiro Kawahata, Rizky Abdulah, Takuya Sasaki

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…Both chemotypes covalently modify SYK-tSH2 and inhibit its interaction with FCER1G p-ITAM, however, these compounds lack selectivity and this limits their utility as chemical tools.…”
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Soil Physicochemical Properties Variation under Annual Crop and Coffee Landuse in the Chentale Watershed, Upper Blue Nile Basin, Ethiopia by Feven Azene Tebekew, Teshome Betru Tadesse, Desta Adane Alemu, Amsalu Awoke Ayalew

“…However, most of the physical and chemical properties of the soil did not vary significantly with depth. …”
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Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons by Amir T. Marvian, Tabea Strauss, Qilin Tang, Benjamin J. Tuck, Sophie Keeling, Daniel Rüdiger, Negar Mirzazadeh Dizaji, Hossein Mohammad-Beigi, Brigitte Nuscher, Pijush Chakraborty, Duncan S. Sutherland, William A. McEwan, Thomas Köglsperger, Stefan Zahler, Markus Zweckstetter, Stefan F. Lichtenthaler, Wolfgang Wurst, Sigrid Schwarz, Günter Höglinger

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Modern methods of ablation of malignant tumors of the liver by L. I. Moskvicheva, D. V. Sidorov, M. V. Lozhkin, L. O. Petrov, M. V. Zabelin

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Programming scheduled self-assembly of circadian materials by Gregor Leech, Lauren Melcher, Michelle Chiu, Maya Nugent, Shirlaine Juliano, Lily Burton, Janet Kang, Soo Ji Kim, Sourav Roy, Leila Farhadi, Jennifer L. Ross, Moumita Das, Michael J. Rust, Rae M. Robertson-Anderson

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Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalization by Chuchu Wan, Si He, Quanyong Cheng, Kehan Du, Yuhang Song, Xiang Yu, Hao Jiang, Caili Huang, Jiangping Xu, Cong Ma, Jintao Zhu

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Synthesis and Evaluation of Optical and PET GLP-1 Peptide Analogues for GLP-1R Imaging by Babak Behnam Azad, Vanessa Rota, Lihai Yu, Rebecca Mcgirr, André H. St. Amant, Ting-Yim Lee, Savita Dhanvantari, Leonard G. Luyt PhD

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Synthesis, Anti-Inflammatory Activity, and Docking Simulation of a Novel Styryl Quinolinium Derivative by Mina Todorova, Rumyana Bakalska, Mehran Feizi-Dehnayebi, Ghodsi Mohammadi Ziarani, Mina Pencheva, Kirila Stojnova, Miglena Milusheva, Paraskev Nedialkov, Emiliya Cherneva, Tsonko Kolev, Stoyanka Nikolova

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Prospective de novo drug design with deep interactome learning by Kenneth Atz, Leandro Cotos, Clemens Isert, Maria Håkansson, Dorota Focht, Mattis Hilleke, David F. Nippa, Michael Iff, Jann Ledergerber, Carl C. G. Schiebroek, Valentina Romeo, Jan A. Hiss, Daniel Merk, Petra Schneider, Bernd Kuhn, Uwe Grether, Gisbert Schneider

“…The top-ranking designs are chemically synthesized and computationally, biophysically, and biochemically characterized. …”
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Towards more efficient, more specific, and safer MRI contrast agents: a Portuguese–French collaborative journey by Pinto, Sara Martinho Almeida, Lacerda, Sara, Morfin, Jean-François, Aroso, Rafael Tiago,  Teixeira, Daniela Sofia de Sousa, Garda, Zoltán, Pereira, Maria Miguens,  Geraldes, Carlos Frederico Gusmão Campos, Tóth, Éva

“…Thanks to a collaborative effort between the Centre of Molecular Biophysics in Orléans, France and the Coimbra Chemistry Centre - Institute of Molecular Sciences in Coimbra, Portugal, there have been important advances in the chemistry of MRI probes. …”
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The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Cont... by S. Abramov, S. Sokolovskyi, A. Gozhenko, I. Sobko, G. Titov, V. Gladyshev, M. Khmil, Ugis Kletnieks

“…Due to the well-selected composition of the product, PLANTOR forms a blood clot in the wound through a biophysical process of liquid absorption. Notably, PLANTOR does not contain procoagulant minerals or nanoparticles that could remain in the human body, and therefore does not belong to means with a chemical or biochemical mechanism of action. …”
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