Tumor Cells and Tumor-Associated Macrophages: Secreted Proteins as Potential Targets for Therapy by Marc Baay, Anja Brouwer, Patrick Pauwels, Marc Peeters, Filip Lardon

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Management of a Patient with Metastatic Colorectal Cancer and Liver Metastases by Muhammad Wasif Saif

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Therapies for Mitochondrial Disorders by Kayli Sousa Smyth, Anne Mulvihill

“…Current therapies include increasing mitochondrial biogenesis, the use of antioxidants, dietary approaches, and exercise. …”
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Mitochondrial Quality Control Orchestrates the Symphony of B Cells and Plays Critical Roles in B Cell-Related Diseases by Wuhao Li, Peiyang Cai, Ye Xu, Weihong Tian, Licong Jing, Qiaoyi Lv, Yangjing Zhao, Hui Wang, Qixiang Shao

“…To maintain metabolic homeostasis, mitochondria dynamically adjust their morphology, distribution, and mass via biogenesis, fusion and fission, translocation, and mitophagy. …”
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Dysfunction in Ribosomal Gene Expression in the Hypothalamus and Hippocampus following Chronic Social Defeat Stress in Male Mice as Revealed by RNA-Seq by Dmitry A. Smagin, Irina L. Kovalenko, Anna G. Galyamina, Anatoly O. Bragin, Yuriy L. Orlov, Natalia N. Kudryavtseva

“…This approach may be used to identify a pharmacological treatment of ribosome biogenesis abnormalities in the brain of patients with “ribosomopathies.”…”
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tRNA-derived small RNAs: their role in the mechanisms, biomarkers, and therapeutic strategies of colorectal cancer by Bo Zhang, Yanru Pan, Zhe Li, Kefeng Hu

“…Although the clinical application of tsRNAs is still in its early stages, recent findings highlight a close relationship between the biogenesis and function of tsRNAs, tRNA chemical modifications, and the tumor immune microenvironment (TIME). …”
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Parkinson’s disease and exosomes: from pathogenesis to diagnosis and treatment by A. Mišeikaitė, P. Vaitkienė

“…The article reviews the biogenesis of exosomes and their potential roles in the diagnosis, treatment, and long-term outcome of Parkinson’s disease. …”
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Two Brothers with Bardet-Biedl Syndrome Presenting with Chronic Renal Failure by Cem Sahin, Bulent Huddam, Gulhan Akbaba, Hasan Tunca, Emine Koca, Mustafa Levent

“…All of the defined BBS genes have been shown to be related to the biogenesis or function of cilia. Renal failure accompanying the syndrome, especially in the advanced stages, is the most common cause of mortality. …”
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Effect of Phosphate Starvation on Gene Expression in <i>Komagataella phaffii</i> Cells by Valeria V. Ishtuganova, Anton V. Sidorin, Anastasiya S. Makeeva, Marina V. Padkina, Andrey M. Rumyantsev

“…In this case, there was a suppression of ribosome biogenesis genes and genes involved in fatty acid beta-oxidation and translation processes.…”
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Extracellular vesicular microRNAs and cardiac hypertrophy by Hai Hu, Hai Hu, Xiulian Wang, Hui Yu, Hui Yu, Zhanli Wang

“…In this review, we briefly review recent advancements in EV research, especially on biogenesis, cargoes and its role in cardiac hypertrophy. …”
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Potential Usefulness of Streptococcus pneumoniae Extracellular Membrane Vesicles as Antibacterial Vaccines by Chi-Won Choi, Edmond Changkyun Park, Sung Ho Yun, Sang-Yeop Lee, Seung Il Kim, Gun-Hwa Kim

“…The EMVs of bacteria play important roles in their virulence, biogenesis mechanisms, and host cell interactions. Bacterial EMVs have recently become the focus of attention because of their potential as highly effective vaccines that cause few side effects. …”
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Anti-inflammatory coupled anti-angiogenic airway stent effectively suppresses tracheal in-stents restenosis by Yanan Zhao, Yiming Liu, Jiheng Shan, Xiaohong Xu, Chengzhi Zhang, Zaoqu Liu, Xiaomeng Li, Zhaoqian Zhong, Yanxia Gao, Kewei Ren, Dechao Jiao, Jianzhuang Ren, Ping Wu, Yong Jiang, Xinwei Han

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Fermented sugarcane juice-derived probiotic Levilactobacillus brevis RAMULAB54 enhances lipid metabolism and glucose homeostasis through PPAR-γ activation by V. B. Chandana Kumari, Ramith Ramu, Sujay S. Huligere, Shashank M. Patil, Shivasharanappa Nayakvadi, Sharath Bijoor, Uma Venkateswaran Manjappara, Mohammad Z. Ahmed, Ling Shing Wong

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Isolation and Characterization of Human Synovial Fluid-Derived Mesenchymal Stromal Cells from Popliteal Cyst by Fang Li, Jianglin Chen, Mengjia Gong, Yang Bi, Chengchen Hu, Yuanyuan Zhang, Ming Li

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The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal Stem/Stromal Cells by Fernanda Vieira Paladino, Juliana de Moraes Rodrigues, Aline da Silva, Anna Carla Goldberg

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Protective Actions of PPAR-γ Activation in Renal Endothelium by Peter E. Westerweel, Marianne C. Verhaar

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Combined Effects of Pericytes in the Tumor Microenvironment by Aline Lopes Ribeiro, Oswaldo Keith Okamoto

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PD-L1 knockout or ZG16 overexpression inhibits PDAC progression and modulates TAM polarization by Hui Meng, Manman Nan, Yizhen Li, Yi Ding, Xiaokun Fang, Weiqian Ma, Mingzhi Zhang

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The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models by Adam B. Glick

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Emerging Roles of BAI Adhesion-GPCRs in Synapse Development and Plasticity by Joseph G. Duman, Yen-Kuei Tu, Kimberley F. Tolias

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