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Does Adiponectin Act as an Antiangiogenic Factor in B-Cell Chronic Lymphocytic Leukemia?
Published 2009-01-01Get full text
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Biometabolic Distribution of Tc-3PRGD2 and its Potential Value in Monitoring Chemotherapeutic Effects
Published 2015-12-01Get full text
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429
The role of Nrf2 transcription factors in various physiological and pathological states
Published 2024-07-01“…Initially recognized for its role in cellular response to oxidative stress, Nrf2 is now known to be involved in a variety of regulatory process, including metabolic regulation, autophagy, protein homeostasis (proteostasis), and mitochondrial biogenesis. The expression of Nrf2 target genes is highly dependent on stimulus activation and interactions with transcription factors, activators, and repressors. …”
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tRNA modifications: greasing the wheels of translation and beyond
Published 2025-12-01“…In this review, we discuss the biogenesis and molecular mechanisms of tRNA modifications, including major tRNA modifications, writer enzymes, and their dynamic regulation. …”
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Protein Machineries Involved in the Attachment of Heme to Cytochrome c: Protein Structures and Molecular Mechanisms
Published 2013-01-01“…This posttranslational process, known as Cyt c biogenesis or Cyt c maturation, ensures the stereospecific formation of the thioether bonds between the heme vinyl groups and the cysteine thiols of the apoCyt heme binding motif. …”
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Emerging role of exosomes in cancer therapy: progress and challenges
Published 2025-01-01“…Abstract This review highlights recent progress in exosome-based drug delivery for cancer therapy, covering exosome biogenesis, cargo selection mechanisms, and their application across multiple cancer types. …”
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The Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes
Published 2014-01-01“…This is because protein components of the RC are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis and maintenance of mitochondria, including mitochondrial DNA (mtDNA) replication, transcription, and translation, require nuclear-encoded genes. …”
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Biology of extracellular vesicles and the potential of tumor-derived vesicles for subverting immunotherapy of cancer
Published 2025-01-01“…EVs are heterogeneous in size, biogenesis, molecular/genetic content and functions. …”
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Signal Transduction of Sphingosine-1-Phosphate G Protein—Coupled Receptors
Published 2006-01-01Get full text
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TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles
Published 2025-02-01“…Nevertheless, whether TGF-β signaling coordinates EV biogenesis is a relevant topic that remains minimally explored. …”
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Impaired Resolution of Inflammation in the Endoglin Heterozygous Mouse Model of Chronic Colitis
Published 2014-01-01Get full text
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