Carcinoma hepatocelular gigante en hígado cirrótico. Presentación de un caso y revisión de la literatura by Jorge Luis Montes de Oca Mastrapa, Johnny Pérez Betancourt, Alejandro Cisneros Carmenate

“…Por ultrasonografía abdominal y tomografía simple y contrastada se realizó el diagnóstico inicial de un carcinoma hepatocelular gigante de más de 16 centímetros en segmentos II y III. …”
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"Hot Issue" no Mercado de IPO e suas Consequências para as Empresas Emitentes e Investidores: o Mercado do Reino Unido em 2000 by João Batista Amorim Toniato

“…Este trabalho oferece a evidência de cincos estudos clínicos realizados no Mercado IPO em 2000 no Reino Unido, sugerindo que os mercados chamados de "Hot Issue" intensificam duas outras anomalias bem documentadas na área de finanças: o underpricing inicial e o desempenho inferior em longo prazo de emissões novas. …”
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RNAI-MEDIATED SILENCING OF MATRIX METALLOPROTEINASE 1 IN EPIDERMAL KERATINOCYTES INFLUENCES THE BIOLOGICAL EFFECTS OF INTERLEUKIN 17A by J. A. Mogulevtseva, A. V. Mezentsev, S. A. Bruskin

“…Thus, MMP1-deficiency in epidermal keratinocytes can be beneficial for psoriasis patients that experience an accumulation of IL-17 in lesional skin. Knocking MMP1 down could influence migration and proliferation of epidermal keratinocytes in vivo, as well as help to control the expression of MMP1, -2, -9 и -12, CCNA2, CCND1, KRT14 and -17 that are crucial for the pathogenesis of psoriasis.…”
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Educación en adultos mayores, mito o realidad by Luis Rodrigo Muñoz Correa

“…El éxito radica en una buena valoración inicial, determinar necesidades individuales y grupales, para así planificar y ejecutar una educación dirigida y acorde a las carencias del grupo, por lo que es fundamental apuntar al fortalecimiento de la autoestima, así lo plantea C. …”
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Endoplasmic Reticulum Stress Regulates Scleral Remodeling in a Guinea Pig Model of Form-Deprivation Myopia by Chengcheng Zhu, Qingzhong Chen, Ying Yuan, Min Li, Bilian Ke

“…Scleral fibroblasts from guinea pigs were cultured and exposed to the ER stress inducer tunicamycin (TM) or the ER stress inhibitor 4-phenylbutyric acid (4-PBA). CRT was knocked down by lentivirus-mediated CRT shRNA transfection. …”
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Heterogeneity of cancer-associated fibroblast subpopulations in prostate cancer: Implications for prognosis and immunotherapy by Chen Ding, Jiange Wang, Jie Wang, Jiqiang Niu, Zhikai Xiahou, Zhou Sun, Zhenzhen Zhao, Dongyang Zeng

“…In vitro experiments verified that the T transcription factor NFAT5 of C1 ABCA8+ fibroblasts subpopulation was knocked down in LNCaP clone FGC and 22Rv1 cell lines, which was closely related to the proliferation of PC. …”
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Molecular subtype of gastric cancer based on apoptosis-related genes reveals differential immune microenvironment and intratumoral microorganisms distribution by Xuan Yu, Yongfu Shao, Haotian Dong, Jianing Yan, Xinjun Zhang, Guoliang Ye

“…Furthermore, PCR assays validated that these three key genes exhibited significantly low expression levels in both GC cell lines and tissues. Finally, knocking down key genes expression significantly promoted cell proliferation, colony formation and invasion of GC. …”
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A REVITIMIZAÇÃO DAS MULHERES EM MINAS GERAIS by Gabriela Maia Salomão, Ana Carolina Souto Fernandes, Izabela Rebentisch Santos Silva, Ludmila Ribeiro

“…Para tanto, foi realizado um exame inicial de todos os acórdãos que tratam de temas interseccionais envolvendo a aplicação da Lei Maria da Penha (LMP) (Lei 11.340/2006), como violência de gênero, guarda, alimentos e outras. …”
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Informe geomorfológico área a afectar por las represas hidroeléctricas Chiuidos I y Chihuidos II-río Neuquén. by Olga Capua

“…El presente trabajo se realizó a partir de un Convenio entre la UNC -Facultad de Humanidades- y Agua y Energía de la Nación, Delegación Alto Valle. …”
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Educación patrimonial: necesidades sentidas por el profesorado de infantil, primaria y secundaria by Leticia CASTRO CALVIÑO, Ramón LÓPEZ FACAL

“…Este estudio muestra varias líneas en las que sería deseable trabajar para la implementación de programas o prácticas de educación patrimonial: la adecuación de los diseños al diagnóstico de necesidades, la incidencia en la formación en educación patrimonial tanto inicial como continua del profesorado y la relación y vinculación de los programas con el entorno local de los centros.…”
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Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhanced Proangiogenic Potential of Cardiac Fibroblasts via Angiopoietin-Like 4 by Jiejie Li, Xin Xu, Suyan Fei, Ren Wang, Hua Wang, Wei Zhu, Yuanyuan Zhao

“…The proangiogenic potential of CFs was decreased when Angptl4 was knocked down in CFs and in hucMSCs. Conclusions. The sEVs regulated CFs to promote angiogenesis via Angptl4 in an inflammatory environment. …”
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ENSINO DE LÍNGUA ESPANHOLA NA EDUCAÇÃO PROFISSIONAL E TECNOLÓGICA by Renata Costa Fonseca Artiles, Thiago Soares de Oliveira

“…No âmbito da Educação Profissional e Tecnológica, o CELIFF emerge no sentido de fomentar a capacitação, seja como como formação inicial, seja como formação continuada, a fim de atender as demandas da contemporaneidade, considerando, inclusive, a similaridade com a Língua Portuguesa e o advento do Tratado do Mercosul. …”
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IMPACTO DE UM PROGRAMA DE INTERVENÇÃO PARA MUDANÇA DO ESTILO DE VIDA SOBRE INDICADORES DE APTIDÃO FÍSICA, OBESIDADE E INGESTÃO ALIMENTAR DE INDIVÍDUOS ADULTOS by Christianne de Faria Coelho, Avany Fernandes Pereira, Fabrício César de Paula Ravagnani, Edilaine Michelin, José Eduardo Corrente, Roberto Carlos Burini

“…No período de 2001-2004, 104 indivíduos (77 mulheres e 27 homens; 54,04±7,7 anos) preencheram os critérios deinclusão comparecendo a sessões de exercícios físicos supervisionados, a reuniões nutricionaise avaliações a cada seis meses por dois anos. Após triagem médica inicial, para exclusão de doençasincapacitantes à atividade motora, foram avaliados o consumo alimentar, antropometriae aptidão física. …”
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Nueva Enfermedad de Schizolobium parahybum (Vell.) S.F. Blake (pachaco) en Plantaciones del Trópico Húmedo Ecuatoriano by Carlos Belezaca Pinargote, Alex Paul Solano Apuntes, Brithany Michelle Belezaca Pinargote, Edison Hidalgo Solano Apuntes, Marcelino Santiago Guachambala Cando, Paola Eunice Díaz Navarrete

“…La incidencia de la enfermedad fue baja (1,7% = 13 árboles enfermos ha-1), con severidad en categoría 2, lo cual indica que están en un estado inicial de la enfermedad. Los árboles enfermos mostraron pérdida de turgencia, palidez y amarillamiento de foliolos, con hojas jóvenes de tamaño reducido, y mala formación. …”
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Conducting and automating the water Morris maze test in SPF conditions by N. V. Khotskin, V. A. Kulikov, E. L. Zavyalov, D. V. Fursenko, A. V. Kulikov

“…With this installation, we were able to study the spatial ability to learn and spatial memory in mice of the C57BL/6 strain and in mice of the C57BL/6/ Kaiso strain developed on the C57BL/6 background, with the gene encoding the methyl-DNA binding Kaiso protein knocked-out. It has been demonstrated that mice of these strains are able to learn to find the platform in the water Morris maze and have the location of the platform in their memory for at least the next four days.…”
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Electricity Generation from Cow Dung Biogas by J. Akpojaro, G. Ofualagba, M.A. Akpojaro

“…We successfully modified the internal combustion engine, which works smoothly without any sign of audible knocking during the entire experimentation. Comparatively, results show that 1.8kg of biogas runs for 127 minutes with a load capacity of 1400 watts while 1 liter of fuel runs on the power generating system with a load input of 1400 watt. 1 liter of fuel operated on the power generating system for a period of 42 minutes after which the system shutdown due to complete consumption of the available fuel. …”
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Interrelación humanos-naturaleza en el Departamento Magallanes, Santa Cruz, Patagonia Argentina by Larry Andrade, Carla Araceli Moscardi, Fernando Salomone

“… La Meseta Central Santacruceña fue ocupada productivamente con ovinos a fines de 1800 y principios de 1900. La productividad inicial del pastizal natural, que soportó altas cargas instantáneas, llevó a no tener en cuenta el impacto que el pastoreo año redondo trajo consigo y que llevaría, en años posteriores, al agotamiento de ese recurso. …”
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Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo by Chien-Wei Feng, Nan-Fu Chen, Te-Fu Chan, Wu-Fu Chen

“…PTP1B inhibition also reversed 6-hydroxydopamine- (6-OHDA-) induced downregulation of phospho-cAMP response element-binding protein (p-CREB) and brain-derived neurotrophic factor (BDNF) in SH-SY5Y cells. Besides, we knocked down and overexpressed PTP1B in the SH-SY5Y cells to confirm its role in neuroprotection. …”
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Contenido y características de la ivermectina en fórmulas magistrales by Jenny Rosalyn Huerta León, Jhonnel Williams Samaniego Joaquin, Jessica Benites Guerrero, Haydee Reyes de la Cruz, Lizbeth Sánchez Pillaca, Luz Mery Tito Quispe, Gerson Córdova Serrano

“…En Perú, la ivermectina se propuso como tratamiento inicial por su supuesta seguridad, recomendándose para reducir la carga viral. …”
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Expansión urbana y transformación de coberturas y usos de suelo en la Aglomeración Urbana de Murcia by Rubén Giménez García, Ramón García Marín

“…La conjunción de ambos fenómenos urbanos, concentración inicial y posterior desconcentración, ha provocado infinidad de cambios en las coberturas y usos de suelo que precisan examen. …”
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