KDM6A facilitates Xist upregulation at the onset of X inactivation by Josephine Lin, Jinli Zhang, Li Ma, He Fang, Rui Ma, Camille Groneck, Galina N. Filippova, Xinxian Deng, Chizuru Kinoshita, Jessica E. Young, Wenxiu Ma, Christine M. Disteche, Joel B. Berletch

“…This was associated with aberrant overexpression of genes from the Xi after differentiation, indicating loss of X inactivation potency. Consistent with KDM6A having a direct role in Xist regulation, we found that the histone demethylase binds to the Xist promoter and KO cells show an increase in H3K27me3 at Xist, consistent with reduced expression. …”
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Efek Pemberian Vitamin C terhadap Gambaran Histopatologi Hati Tikus Wistar yang Terpapar Timbal Asetat by Arifuddin ., Aswiyanti Asri, Elmatris .

“…Vitamin C is a natural compound as potent antioxidant and free radical binding.The objective of this study was to determine the effect of vitamin C on liver histopathology in exposed lead acetate wistar rats. …”
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Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia by Jana Lücht, Nele Rolfs, Sylvia J. Wowro, Felix Berger, Katharina R. L. Schmitt, Giang Tong

“…However, cooling resulted in a significant decrease of extracellular CIRBP, which has recently been characterized as a novel DAMP and a potent initiator and mediator of inflammation.…”
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Pemeriksaan Laboratorium Cystatin C Untuk Uji Fungsi Ginjal by Rismawati Yaswir, Afrida Maiyesi

“…Untuk menilai penurunan LFG, nilai sensitivitas, spesifisitas, dan efisiensi diagnostik CysC yang paling baik (98%) didapatkan jika digunakan titik potong batas atas kadar CysC 1,31 mg/l. Pemeriksaaan kadar CysC urine dapat dilakukan untuk mengetahui adanya disfungsi tubulus proksimal. …”
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Approaches to modulate buffalo gut microbiome for efficient feed utilization and reduced environmental pollution by Vijit Dey, Puran C. Lailer, Tirtha K. Datta

“…At the same time, ammonia is a potent environmental pollutant and is liable for the depletion of oxygen in the body water, reduction of soil pH, and generation of harmful aerosol fine particles accompanied by the augmented menace of pulmonary diseases. …”
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Incidence of self-reported tuberculosis treatment with community-wide universal testing and treatment for HIV and tuberculosis screening in Zambia and South Africa: A planned analy... by L Telisinghe, S Floyd, D MacLeod, A Schaap, R Dunbar, J Bwalya, N Bell-Mandla, E Piwowar-Manning, D Donnell, K Shaunaube, P Bock, S Fidler, R J Hayes, H M Ayles, HPTN 071 (PopART) study team

“…<h4>Background</h4>HIV is a potent risk factor for tuberculosis (TB). Therefore, community-wide universal testing and treatment for HIV (UTT) could contribute to TB control, but evidence for this is limited. …”
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Hubungan Faktor Risiko Terhadap Kejadian Sindroma Koroner Akut pada Pasien Dewasa Muda di RSUP Dr. M. Djamil Padang by Anggita Tiara Pramadiaz, Muhammad Fadil, Henny Mulyani

“…Tujuan penelitian ini adalah menentukan hubungan faktor risiko dengan kejadian SKA pada dewasa muda..Ini merupakan penelitian analitik observasional dengan desain potong lintang yang dilakukan di RSUP.M. Djamil Padang dari Juni 2014 sampai Oktober 2014. …”
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Acid-Unlocked Two-Layer Ca-Loaded Nanoplatform to Interfere With Mitochondria for Synergistic Tumor Therapy by Zheng Y, Williams GR, Hu R, Tong S, Xu J, Wang T, Zhang Y, Wu J, Li F, Cai Y, Zhu LM

“…Yilu Zheng,1 Gareth R Williams,2 Ran Hu,1 Sen Tong,3 Jianxiang Xu,1 Tong Wang,1 Yanyan Zhang,1 Junzi Wu,3 Fan Li,4 Yingyu Cai,4 Li-Min Zhu1 1College of Biological Science and Medical Engineering, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, Donghua University, Shanghai, 201620, People’s Republic of China; 2UCL School of Pharmacy, University College London, London, WC1N 1AX, UK; 3The Key Laboratory of Microcosmic Syndrome Differentiation, Education Department of Yunnan, Yunnan University of Chinese Medicine, Kunming, 650500, People’s Republic of China; 4Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, People’s Republic of ChinaCorrespondence: Yingyu Cai, Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, People’s Republic of China, Email yingyu.cai@shgh.cn Li-Min Zhu, College of Biological Science and Medical Engineering, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, Donghua University, Shanghai, 201620, People’s Republic of China, Email lzhu@dhu.edu.cnBackground: The development of selective formulations able to target and kill tumor cells without the application of external energy has shown great promise for anti-tumor therapy.Methods: Here, we report a “nanobomb” that explosively increases Ca content within cells. …”
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When specific exercise is more effective than medication - Sensorimotor training is currently the most promising option to treat and prevent chemotherapy-induced peripheral neuropa... by Fiona Streckmann, Maryam Balke, Céline Hammadou, Bianca Schmidli, Oliver Faude, Sarah Koch

“…., Oschwald, V., Koliamitra, C., Otten, S., Draube, A., Heinen, P., Steinmetz, T., Hallek, M., Leitzmann, M., Bloch, W., & Balke, M. (2024). …”
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Improving Growth Performance, Biochemical Parameters and Reducing Mortality due to Ascites in Broilers by Propranolol Inclusion by Shahriar Saidian, Somaya Farahmand, Mokhtar Fathi, Salar Saifi

“…Of the five b-blockers examined, propranolol was the most potent agent, and the activities seemed to correlate with the drugs’ hydrophobicity. …”
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Application of Concentration-Area fractal modeling and artificial neural network to identify Cu, Zn±Pb geochemical anomalies in Hashtjin area, NW of Iran by Ali Imamalipour, Hamed Ebrahimi, Amir reza Abdollahpur

“…Considering the evidence of the fractal nature of element distribution, the use of these methods in geochemical exploration for separating anomalous populations from the background with high confidence levels is one of the most potent known methods. The concentration-area fractal method is based on the amount of area occupied by a particular concentration in the study area. …”
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Analysis of the Effect of Social Capital on Brand Performance with the Mediating Role of Employees’ Brand Citizenship Behavior by Naser Seifollahi

“…Social capital has been defined as the total of real and potential resources hidden inside, available and emerging from the network of relationships belonging to an individual or social unit (Joeng & et al, 2021). According to Putnam, social capital refers to the connections between people - social networks and mutual and reliable norms that arise from them. …”
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Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2<small.letters>dmepda</small.letters>H<mml:math> <mml:mrow>...

“…The 1,10-phenanthroline containing complex [Cu(2dmepda)(phen)<mml:math> <mml:mrow> <mml:msub> <mml:mrow> <mml:mrow><mml:mrow> <mml:mrow><mml:mo>(</mml:mo> <mml:mrow><mml:msub> <mml:mtext>H</mml:mtext> <mml:mn>2</mml:mn> </mml:msub> <mml:mtext>O</mml:mtext> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow> </mml:mrow> <mml:mo>]</mml:mo></mml:mrow> </mml:mrow> <mml:mn>2</mml:mn> </mml:msub> </mml:mrow> </mml:math>0.5phen (<bold>3</bold>) was the most potent with activity that compares well to that of <emph>cis</emph>platin.…”
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Summatory Multiplicative Arithmetic Functions: Scaling and Renormalization by Leonid G. Fel

“…We apply the derived formulas to a large number of basic summatory functions including the Euler <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>ϕ</mi><mo>(</mo><mi>k</mi><mo>)</mo></mrow></semantics></math></inline-formula> and Dedekind <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>ψ</mi><mo>(</mo><mi>k</mi><mo>)</mo></mrow></semantics></math></inline-formula> totient functions, divisor <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>σ</mi><mi>n</mi></msub><mrow><mo>(</mo><mi>k</mi><mo>)</mo></mrow></mrow></semantics></math></inline-formula> and prime divisor <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>β</mi><mo>(</mo><mi>k</mi><mo>)</mo></mrow></semantics></math></inline-formula> functions, the Ramanujan sum <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>C</mi><mi>q</mi></msub><mrow><mo>(</mo><mi>n</mi><mo>)</mo></mrow></mrow></semantics></math></inline-formula> and Ramanujan <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>τ</mi></semantics></math></inline-formula> Dirichlet series, and others.…”
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