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2581
Cumhuriyet ile Yaşıt Bir Kültürel Miras: Tarihi Tire Bandosu
Published 2025-01-01“…Yüzüncü yaşını doldurmuş olan bando her cuma akşamüstü bayrak töreni için Tire meydanında çalmakta, resmi bayramlarda ve törenlerde görevlerini yerine getirmektedir. 1923 yılında kurtuluş savaşı sonunda Yunan işgali biter. …”
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2582
Metal-Based Antibacterial and Antifungal Agents: Synthesis, Characterization, and In Vitro Biological Evaluation of Co(II), Cu(II), Ni(II), and Zn(II) Complexes with Amino Acid-Der...
Published 2006-01-01“…Five compounds, (3), (7), (10), (11), and (22), displayed potent cytotoxic activity as LD50=8.974×10-4,7.022×10-4,8.839×10-4,7.133×10-4, and 9.725×10-4 M/mL, respectively, against Artemia salina.…”
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2583
Apigenin inhibits NLRP3 inflammasome activation in monocytes and macrophages independently of CD38
Published 2025-01-01“…CD38 inhibition with 78c also attenuated NLRP3-dependent IL-1β release. Apigenin was a potent inhibitor of Ca2+ flux from the endoplasmic reticulum to the cytosol in human monocyte-derived macrophages. …”
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2584
Spectroscopic analysis (UV-VIS-NIR) for predictive modeling of macro and micronutrients in grapevine leaves
Published 2025-03-01“…Diffuse reflectance spectroscopy coupled with chemometric methods emerges as a potent, cost-effective, and environmentally friendly analytical technique for determining nutrient concentrations in plants. …”
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2585
Wu-Mei-Wan enhances brown adipose tissue function and white adipose browning in obese mice via upregulation of HSF1
Published 2025-01-01“…Conclusions WMW represents a potent therapeutic strategy for obesity, promoting metabolic health and beneficial modulation of adipose tissue through an HSF1-dependent pathway.…”
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2586
Deciphering In Vitro and In Vivo Pharmacological Properties of Seed and Fruit Extracts of Flacourtia jangomas (Lour.) Raeusch
Published 2024-01-01“…In the protein denaturation antiarthritic test, the PFJE and SFJC extracts exhibited significant potency, achieving results of 74.28 ± 1.16% and 79.25 ± 0.83%, respectively, at a dose of 500 μg/mL. …”
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2587
Nanoparticles for Biomedical Use Derived from Natural Biomolecules: Tannic Acid and Arginine
Published 2025-01-01“…The antioxidant capacity of p(TA-co-ARG) particles via gallic acid (GA) and rosmarinic acid (RA) equivalents tests revealed that particles possess concentration-dependent antioxidant potency and increased by TA content. The α-glucosidase inhibition of p(TA-co-ARG) particles (2 mg/mL) 1:1 and 1:2 mole ratios revealed significant enzyme inhibition ability, e.g., 91.3 ± 3.1% and 77.6 ± 12.0%. …”
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2588
Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice
Published 2025-01-01“…Results The tumor-targeted L19-IL2 fusion protein demonstrated potent, dose-dependent anti-tumor activity in mice with pancreatic tumors resistant to standard chemotherapy. …”
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2589
Trends in Prescription of Stimulants and Narcoleptic Drugs in Switzerland: Longitudinal Health Insurance Claims Analysis for the Years 2014-2021
Published 2025-01-01“… Abstract BackgroundStimulants are potent treatments for central hypersomnolence disorders or attention-deficit/hyperactivity disorders/attention deficit disorders but concerns have been raised about their potential negative consequences and their increasing prescription rates. …”
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2590
Perbandingan Kadar Ureum dan Kreatinin Serum Masyarakat Terpapar dengan Tidak Terpapar Emisi Pabrik PT. Semen Padang
Published 2018-07-01“…Penelitian ini merupakan penelitian analitik dengan rancangan potong lintang terhadap 152 subjek terpapar dan 169 subjek tidak terpapar dari bulan Juni 2015-September 2016. …”
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2591
Case-Based Virtual Reality Simulation for Severe Pelvic Trauma Clinical Skill Training in Medical Students: Design and Pilot Study
Published 2025-01-01“…ObjectiveThis study aims to introduce a novel experimental teaching methodology for severe pelvic trauma, integrating virtual reality (VR) technology as a potent adjunct to existing teaching practices. It evaluates the acceptability, perceived ease of use, and perceived usefulness among users and investigates its impact on knowledge, skills, and confidence in managing severe pelvic trauma before and after engaging with the software. …”
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2592
Electronegative LDL from Rabbits Fed with Atherogenic Diet Is Highly Proinflammatory
Published 2019-01-01“…Taken together, our results show that rabbits fed with atherogenic diet produce a highly proinflammatory LDL(-) that is more potent in inducing inflammation than nLDL and extensively oxidize LDL in macrophages. …”
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2593
Integrative computational analysis of anti-influenza potential in Caesalpinia mimosoides Lamk hydroethanolic extract
Published 2025-02-01“…The C. mimosoides hydroethanolic extract exhibited potent antioxidant activity in the DPPH assay, with an IC50 value of 15.01 µg/mL, comparable to authentic quercetin (IC50 = 12.72 µg/mL) and approximately 4.91 times greater than standard gallic acid (IC50 = 3.06 µg/mL). …”
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2594
Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms
Published 2025-01-01“…Clove oil (CLO), a common aromatic spice, has been used as a traditional medication as it has potent anti-inflammatory, antioxidant, and hepatoprotective properties. …”
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2595
Transparencia algorítmica ¿un problema normativo o tecnológico?
Published 2021-12-01“…Los algoritmos de aprendizaje automático, por su parte, constituyen una tecnología idónea para obtener una automatización de procesos más sofisticada, pues supone acceder a reglas más inteligentes, potentes y flexibles, que se van corrigiendo a medida que los datos de la muestra van evolucionando y reconociendo variaciones en función de muchísimos factores. …”
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2596
hAMSCs regulate EMT in the progression of experimental pulmonary fibrosis through delivering miR-181a-5p targeting TGFBR1
Published 2025-01-01“…A previous study has found that miR-181a-5p plays an important role in the development of PF, and human amniotic mesenchymal stem cells (hAMSCs) exert potent therapeutic potential on PF. However, whether hAMSCs act on PF by delivering miR-181a-5p and its detailed mechanism still remain unknown. …”
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2597
Glucagon-Like Peptide-2 Analogue ZP1849 Augments Colonic Anastomotic Wound Healing
Published 2020-01-01“…The enteroendocrine hormone glucagon-like peptide- (GLP-) 2 is a potent trophic factor in the gastrointestinal tract. …”
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2598
Evaluating Avacopan in the Treatment of ANCA-Associated Vasculitis: Design, Development and Positioning of Therapy
Published 2025-01-01“…Box 9600, Leiden, 2300 RC, the Netherlands, Tel +31-71-5262148, Fax +31-71-5266868, Email Y.K.O.Teng@lumc.nlAbstract: Recently, avacopan has been approved for the treatment of ANCA-associated vasculitis (AAV). …”
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2599
Synergistic antimicrobial activity of essential oils mixture of Moringa oleifera, Cinnamomum verum and Nigella sativa against Staphylococcus aureus using L-optimal mixture design
Published 2025-01-01“…Statistical modeling revealed cinnamon oil had the highest individual antimicrobial potency, followed by black seed oil. The combination of the three EOs exhibited significant synergistic effects compared to the individual oils, with a Fractional Inhibitory Concentration (∑FIC) index of 0.27. …”
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2600
Unveiling prognostic value of JAK/STAT signaling pathway related genes in colorectal cancer: a study of Mendelian randomization analysis
Published 2025-02-01“…And MPP2 exhibited the most potent activating influence on the cell cycle pathway, whereas ANK3 demonstrated the most significant inhibitory effect within the apoptosis pathway. …”
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