Radiological Staging of Thyroid-Associated Ophthalmopathy: Comparison of T1 Mapping with Conventional MRI by Lu Chen, Wen Chen, Huan-Huan Chen, Qian Wu, Xiao-Quan Xu, Hao Hu, Fei-Yun Wu

“…Our findings suggest that the T1-mapping technique holds the potency to be utilized in TAO. The derived T1RTCS of EOMs, which may be associated with fat infiltration, could be a useful biomarker to stage the disease, serving added efficiency, sensitivity, and specificity to single usage of conventional SIR.…”
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Anti-furfurative comparison of Kesh Kanti-Herbal Shampoos and synthetic shampoos against Malassezia furfur for dandruff management by Acharya Balkrishna, Nem Kumar Ngpoore, Harshita Jonwal, Savita Lochab, Anurag Varshney

“…Comprehensive ingredient analysis revealed the robust antifungal activity in SYN_01 was probably because of the presence of various surfactants, allergens and a potent synthetic antifungal agent, Piroctone olamine. …”
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The beneficial effects of curcumin on aging and age-related diseases: from oxidative stress to antioxidant mechanisms, brain health and apoptosis by Ying He, Ying He, Yongqing Liu, Min Zhang

“…Furthermore, curcumin has a potent inhibitory effect on the activity of nuclear factor kappa B (NF-κB) and cyclooxygenase-2 (COX-2), which are involved in the overexpression of antiapoptosis genes such as Bcl-2. …”
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Characterization of a Novel Tc-Carbonyl Complex as a Functional Probe of P-Glycoprotein Transport Activity by Mary Dyszlewski, Helen M. Blake, Julie L. Dahlheimer, Christina M. Pica, David Piwnica-Worms

“…In KB 8-5 cells, tracer enhancement was observed with the potent MDR modulator LY335979 (EC 50 = 62 nM). Similar behavior was observed using drug-sensitive MCF-7 breast adenocarcinoma cells and MCF-7/ MDR1 stable transfectants, confirming that Tc-CO-MIBI is specifically excluded by overexpression of MDR1 Pgp. …”
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Hubungan Suplementasi Tablet Fe dengan Kadar Hemoglobin pada Ibu Hamil Trimester III di Puskesmas Air Dingin Kota Padang by Fadina Rizki, Nur Indrawati Lipoeto, Hirowati Ali

“…Rancangan penelitian berupa studi potong lintang dan teknik pengambilan sampel dengan metode proportional random sampling. …”
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Duvelisib is a novel NFAT inhibitor that mitigates adalimumab-induced immunogenicity by Aboli Bhingarkar, Yuyin Wang, Keito Hoshitsuki, Katherine Marie Eichinger, Katherine Marie Eichinger, Sanjay Rathod, Yin Zhu, He Lyu, Andrew T. McNutt, Larry W. Moreland, Lee McDermott, David R. Koes, Christian A. Fernandez

“…Therefore, developing a potent NFAT inhibitor to suppress this immunogenicity may offer an alternative to MTX.MethodsWe performed a structure-based virtual screen of the NFATC2 crystal structure to identify potential small molecules that could interact with NFATC2. …”
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Accelerating Deep Learning-Based Morphological Biometric Recognition with Field-Programmable Gate Arrays by Nourhan Zayed, Nahed Tawfik, Mervat M. A. Mahmoud, Ahmed Fawzy, Young-Im Cho, Mohamed S. Abdallah

“…Convolutional neural networks (CNNs) are increasingly recognized as an important and potent artificial intelligence approach, widely employed in many computer vision applications, such as facial recognition. …”
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Effects of Resveratrol on the Kidney in Rats with Streptozotocin Induced Diabetic Nephropathy by Duygu Tozcu, Çiğdem Özer, Aydan Babül, Sevim Ercan, Ergin Dileköz, Gülnur Take Kaplanoğlu, Güleser Göktaş

“…Resveratrol (RSV), a natural compound found in grape skins and red wine, has potent antioxidant properties. This study aimed to evaluate the effects of RSV in a streptozotocin (STZ)-induced diabetic rat model. …”
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Biodegradation of rice husks for glucose production using Streptomyces coelicolor STRP-19 by Waleed M. Abdulkhair, Younes M. Rashad, Mohamed Hafez, Ahmed M. Abd-ElGawad, Mohamed Bourouah

“…Although several Streptomyces isolates showed rice husks-degrading activity, STRP-19 isolate was the most potent and was identified as S. coelicolor using phenotypic and genetic methods based on 16S rRNA gene sequencing. …”
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High-level biosynthesis and purification of the antimicrobial peptide Kiadin based on non-chromatographic purification and acid cleavage methods by Liangjun Zheng, Fengyi Yang, Chen Wang, Muhammad Zafir, Zishuo Gao, Pilong Liu, Fatma A. El-Gohary, Xin Zhao, Huping Xue

“…Abstract Antimicrobial peptides (AMPs) are renowned for their potent bacteriostatic activity and safety, rendering them invaluable in animal husbandry, food safety, and medicine. …”
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Actividad larvicida de especies vegetales de la flora salvadoreña para el control de Aedes aegypti by Susana Hernández-Doño, Angélica Dalila Moreno, Eduardo Romero, Rina Antonieta Toledo-Mendoza, Miguel Ángel Serrano-Melgar, Miguel Ángel Moreno-Mendoza, Marvin José Nuñez-Rivas

“…Una fuente de ello lo constituyen las plantas que posean principios activos potentes y con alta estabilidad química con acción insecticida. …”
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Pharmacological Inhibition of Caspase-1 Ameliorates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation in Mice by Jung-Yeon Kim, Jae-Hyung Park, Kiryeong Kim, Jungmin Jo, Jaechan Leem, Kwan-Kyu Park

“…In this study, we examined the effect of Ac-YVAD-cmk, a potent caspase-1-specific inhibitor, on renal function and histology in cisplatin-treated mice and explored its underlying mechanisms. …”
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The Role of PPARs in Lung Fibrosis by Heather F. Lakatos, Thomas H. Thatcher, R. Matthew Kottmann, Tatiana M. Garcia, Richard P. Phipps, Patricia J. Sime

“…The clinical availability of potent and selective PPARα and PPARγ agonists should facilitate rapid development of successful treatment strategies based on current and ongoing research.…”
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Evaluation of the Antimicrobial Effect of the Extracts of the Pods of Piliostigma thonningii (Schumach.) Milne-Redh. (Fabaceae) by Memory Makosa, Simbarashe Sithole, Stanley Mukanganyama

“…The microorganism used for the tests was Pseudomonas aeruginosa, Candida krusei and Mycobacterium smegmatis. The most potent extract was then used to determine its effect on microbial cell membrane integrity. …”
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The Development of Methods of BLOTCHIP^®-MS for Peptidome: Small Samples in Tuberous Sclerosis by Kunio Yui, George Imataka, Kotaro Yuge, Hitomi Sasaki, Tadashi Shiohama, Kyoichi Asada, Hidehisa Tachiki

“…Of reference, everolimus has the best treatment target because of the higher potency of interactions with mTORC2 rather than rapamycin. …”
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β-Hydroxybutyrate Protects Against Cisplatin-Induced Renal Damage via Regulating Ferroptosis by Ruixue Tian, Shuqin Tang, Jingyu Zhao, Yajie Hao, Limei Zhao, Xiutao Han, Xingru Wang, Lijun Zhang, Rongshan Li, Xiaoshuang Zhou

“…Cisplatin is a particularly potent antineoplastic drug. However, its usefulness is restricted due to the induction of nephrotoxicity. …”
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Metabolic and hematological disruptions induced by Diphenyl Diselenide in male wistar rats by Joseph A. Olagunju, Gabriel O. Ajayi, Babatunde A. Murtala, Adejuwan A. Adeneye

“…Diphenyldiselenide (DPDS), a potent antioxidant and enzyme inhibitor, exerts cellular toxicity mainly through interaction with thiol group of proteins. …”
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Mitochondrial dysfunction-driven AMPK-p53 axis activation underpins the anti-hepatocellular carcinoma effects of sulfane sulfur by Xue Zheng, Yuhua Luo, Rui Huo, Yiwen Wang, Youbang Chen, Mianrong Chen, Qi Zhao, Kexin Li, Hanyi Zhang, Xiaotong Li, Xiang Li, Hui Zhang, Zaopeng He, Li Huang, Chun-tao Yang

“…PSCP treatment significantly inhibited HCC tumor growth in an allograft model, reduced cell viability and proliferation, and induced apoptosis. PSCP potently increased p53 expression and induced AMPK phosphorylation in SNU398 HCC cells. …”
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FXR Activation Accelerates Early Phase of Osteoblast Differentiation Through COX-2-PGE₂-EP4 Axis in BMP-2-Induced Mouse Mesenchymal Stem Cells by Ko Fujimori, Yusuke Iguchi, Yukiko Yamashita, Keigo Gohda, Naoki Teno

“…Therefore, a novel FXR agonist, <b>FLG390,</b> exhibited potency comparable to CDCA. FXR activation promoted the early phase of osteoblast differentiation via the COX-2-PGE₂-EP4 axis, representing a potential target for control of bone metabolism.…”
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Molecular Dynamics Insights into Peptide-Based Tetrodotoxin Delivery Nanostructures by Shenghan Song, Xinyu Xia, Temair Shorty, Tongtong Li, Amy O. Stevens, Chao Zhao, Yi He

“…Tetrodotoxin (TTX), a potent Site-1 sodium channel blocker (S1SCB), offers highly effective local anesthetic properties with minimal addiction potential. …”
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