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Advances in TENGs for Marine Energy Harvesting and In Situ Electrochemistry
Published 2025-01-01“…Highlights The basic information of triboelectric nanogenerator (TENG), the power conversion process, and key points of the marine energy harvesting TENGs was introduced in detail. …”
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Implementasi Logika Fuzzy Pada Alat Pendeteksi Kualitas Minyak Goreng Berdasarkan pH dan Tingkat Kejernihan
Published 2024-02-01“… Penelitian ini bertujuan untuk mengembangkan alat pendeteksi kualitas minyak goreng kelapa sawit dengan menggunakan metode fuzzy logic Mamdani yang memanfaatkan sensor pH dan sensor cahaya BH1750. …”
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Potency of Garlic (Allium sativum) Extract Against Motile Aeromonad Septicaemia Disease Caused by Aeromonas hydrophila in Pangasionodon hypophthalmus
Published 2008-01-01“…In our experiment, we study the potency of a phytopharmacia agent, garlic extract for prevention and curing off the experimental infections by Aeromonas hydrophila. …”
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The Potency of Anting Anting (Acalypha indica L.) Leaf Extract as An Acaricide on Boophilus microplus in Larvae and Adult Stages In Vitro
Published 2021-09-01“…The purpose of this study was to determine the potency of anting-anting leaf extract (Acalypha indica L.) as an acaricide against larval and adult Boophilus microplus in vitro by observing the mortality rate of B. microplus. …”
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PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands
Published 2025-01-01“…Here we show that monotherapy with selective PRMT5 inhibitors induced a potent anti-tumor activity across several cellular and animal models of ACC, which was paralleled by downregulation of genes associated with ACC tumorigenesis, including MYB and MYC (the recognized drivers of ACC progression). …”
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An adenosine analog shows high antiviral potency against coronavirus and arenavirus mainly through an unusual base pairing mode
Published 2024-12-01“…The cryo-EM structures of HNC-1664-bound RdRP-RNA complexes from both SARS-CoV-2 and LASV reveal an unusual base pairing mode of HNC-1664 in part due to its base modification, thus revealing its great potency in binding but not catalysis. Under certain circumstances, 1664-TP can be slowly incorporated by RdRP through regular Watson-Crick base pairing, as evidenced by enzymology data and an HNC-1664-incorporated crystal structure of the RdRP-RNA complex. …”
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Structure-Activity Relationships of 3,3′-Phenylmethylene-bis-4-hydroxycoumarins: Selective and Potent Inhibitors of Gram-Positive Bacteria
Published 2013-01-01“…Dicoumarols and coumarin derivatives have shown a variety of pharmaceutical activities and have been found to be potent inhibitor for the NAD(P)H-dependent flavoproteins. …”
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Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro
Published 2025-01-01“…It was shown that compound <b>2a</b> exerted a more potent cytotoxic effect under hypoxic conditions, while compound <b>2a-B</b> demonstrated a comparable effect in normoxic and hypoxic conditions. …”
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DockCADD: A streamlined in silico pipeline for the identification of potent ribosomal S6 Kinase 2 (RSK2) inhibitors
Published 2025-03-01“…Herein, we developed an open-source computational pipeline, identified as DockCADD (available at https://github.com/mehdikariim/DockCADD), which enables the identification of potent RSK2 inhibitors by automated virtual screening, ADME-Tox profiling, and molecular dynamics (MD) simulations. …”
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Identification of dequalinium as a potent inhibitor of human organic cation transporter 2 by machine learning based QSAR model
Published 2025-01-01“…After manual selection and in vitro assays, we found that dequalinium, a quaternary ammonium cation antimicrobial agent, is a potent hOCT2 inhibitor (IC50 = 88.16 ± 7.14 nM). Moreover, dequalinium inhibited hOCT2-mediated transport of platinum anti-cancer agents (cisplatin and oxaliplatin) in a concentration-dependent manner. …”
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