Simultaneous and Consecutive Drainage of Bilateral Chronic Subdural Hematoma: A Randomized Controlled Trial by Omer AKAR, Hasan Kamil SUCU, Selin BOZDAG

“…Patients were followed up during the inpatient period and postoperatively at 1, 3, 6, and 12 months after discharge. Mortality, morbidity, surgical complications, reoperation, and, as a combination of all of these, treatment success rates were compared. …”
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CCR5-ligand decorated rilpivirine lipid-based nanoparticles for sustained antiretroviral responses by Milankumar Patel, Sudipta Panja, Lubaba A. Zaman, Pravin Yeapuri, Shaurav Bhattarai, Santhi Gorantla, Linda Chang, Alonso Heredia, Piotr Walczak, Brandon Hanson, Samuel M. Cohen, Bhavesh D. Kevadiya, Howard E. Gendelman

“…Focused ultrasound with microbubbles mediated blood brain barrier (BBB) disruption allows the CCR5-targeted LBNP to penetrate the BBB and reach brain myeloid cells. …”
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Human Placenta-Derived Mesenchymal Stem Cells Reduce Mortality and Hematoma Size in a Rat Intracerebral Hemorrhage Model in an Acute Phase by Bo Young Choi, Ok Joon Kim, Sae-Hong Min, Jeong Hyun Jeong, Sang Won Suh, Tae Nyoung Chung

“…Intracerebral hemorrhage (ICH) is a critical disease, highly associated with mortality and morbidity. Several studies have demonstrated the beneficial effect of mesenchymal stem cells (MSCs) on ICH, mostly focused on their mid-to-long-term effect. …”
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Diffusion MRI Findings in Encephalopathy Induced by Immunosuppressive Therapy after Liver Transplantation by Emanuele Tinelli, Nicoletta Locuratolo, Alberto Pierallini, Massimo Rossi, Francesco Fattapposta

“…Brain MRI and particularly DWI and ADC maps provide not only a good and early representation of neurological complications during immunosuppressant therapy but can also provide a useful prognostic tool on clinical outcome of the patient.…”
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Effects of Exercise Preconditioning Mediating Oxidative Stress to Regulate PI3K/Akt and Nrf2/HO-1 Pathways to Alleviate Cognitive and Learning Disorders in Rats by KONG Haijun, LI Xinlong, WANG Fenghua, CHEN Xiaoan

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An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis by Rajish Sanjit Kumar Shil, Jamal Ali Teir

“…It is prudent to be vigilant in investigating patients with atypical presentation for systemic autoimmune diseases, as this approach would affect the patient morbidity and mortality with early initiation of treatment for the disease.…”
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Outcomes and predictors of unplanned intensive care unit admission for pediatric trauma patients by Tyler Liang, MD, Areg Grigorian, MD, Robert Painter, MD, James Jeng, MD, Theresa Chin, MD, Laura F. Goodman, MD MPH, Yigit S. Guner, MD, Catherine Kuza, MD, Jeffry Nahmias, MD MHPE

“…Background: Unplanned intensive care unit (ICU) admission (UIA) is associated with increased morbidity in adult trauma patients, however, is not well studied in pediatric trauma patients (PTPs). …”
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Kidney transplant utilising donors after circulatory death: The first report from the African continent by T du Toit, K Manning, L Bertels, G Hoffman, D Thomson, Z A Barday

“…DCD may present a unique opportunity to expand deceased donation throughout Africa, particularly in areas affected by a lack of brain death legislation and religious or cultural objections to donation after brain death. …”
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Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy by Kate Johnson, Ashish Malkan, Mohamed Shaffi

“…CANOMAD is a rare chronic neuropathy, characterized by chronic sensory ataxia and intermittent brain stem symptoms due to antidisialosyl antibodies. …”
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Sjogren–Larsson Syndrome: A Familial Disease Afflicting Three Siblings Born of a Nonconsanguinous Marriage by Aparna Thirumalaiswamy, Saloni Abhijit Desai, Atul Madhusudan Dongre, Chitra Shivanand Nayak

“…The case underscores the importance of early SLS diagnosis to mitigate morbidity and improve the quality of life for affected individuals.…”
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Gender Dysphoria and Its Non-Surgical and Surgical Treatments by Danyon Anderson, Himasa Wijetunge, Peyton Moore, Daniel Provenzano, Nathan Li, Jamal Hasoon, Omar Viswanath, Alan D. Kaye, Ivan Urits

“…The frequency and severity of treatment related morbidity increases progressively as treatments go from conservative to more invasive. …”
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Bone Metastasis as the Only Metastatic Site in a Patient with Pancreatic Cancer following Distal Pancreatectomy by Muhammad Wasif Saif, Natalie Galanina, L. Ravage-Mass, Kristin Kaley, Daniel Cornfeld, Lynne Lamb, David Chhieng

“…Other less common sites are the lung, brain, kidney, and bone. Skeletal metastases are less prevalent in occurrence but contribute to significant morbidity associated with pancreatic cancer. …”
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Impulse Control Disorders in Parkinson’s Disease: Crossroads between Neurology, Psychiatry and Neuroscience by Paulo Bugalho, Albino J. Oliveira-Maia

“…Parkinson disease impulse control disorders (PD-ICDs) have raised significant interest in the scientific and medical community, not only because of their incapacitating nature, but also because they may represent a valid model of ICDs beyond PD and a means to study the physiology of drive, impulse control and compulsive actions in the normal brain. In this review, we discuss some unresolved issues regarding PD-ICDs, including the association with psychiatric co-morbidities such as obsessive-compulsive disorder and with dopamine related side effects, such as hallucinations and dyskinesias; the relationship with executive cognitive dysfunction; and the neural underpinnings of ICDs in PD. …”
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Immunogenetics of longevity and its association with human endogenous retrovirus K by Lisa M. James, Lisa M. James, Lisa M. James, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos

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Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials by Tao Zeng, Lei Li, Yan Zhou, Liang Gao

“…Gliomas are primary brain tumors presumably derived from glial cells. …”
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Toxoplasmosis in Pork Meat: a Health Risk by Mildre Mercedes Vidal del Río, María Fernanda Latorre Barragán, Darwin Rafael Villamarín Barragán, Aldemar Alejandro Monsalve Guamán

“…Toxoplasmosis is a disease caused by a protozoan called Toxoplasma gondii, it manifests itself with great morbidity and mortality in fetuses, newborns and immunocompromised patients, however, toxoplasmosis can also manifest itself in immunocompetent patients suffering from: chorioretinitis, lymphadenopathy, pneumonia, brain abscess, myositis, myocarditis and hepatitis. …”
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Colorectal Metastasis From Lung Adenocarcinoma With Initial Gastrointestinal Symptoms: A Case Report and Literature Review by Yu Xin, Dan Liu, Dan Zang, Yan Sun, Jun Chen

“…ABSTRACT Lung cancer (LC) is a malignant tumor with high morbidity and mortality. Nearly 50% of patients with primary LC have distant metastases at the time of initial diagnosis. …”
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Evidence-Based Cerebral Vasospasm Surveillance by Heather Kistka, Michael C. Dewan, J. Mocco

“…Subarachnoid hemorrhage related to aneurysmal rupture (aSAH) carries significant morbidity and mortality, and its treatment is focused on preventing secondary injury. …”
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Management of Agitation Following Aneurysmal Subarachnoid Hemorrhage: Is There a Role for Beta-Blockers? by Fayaz Ibrahim, Ramaswamy Viswanathan

“…Stroke is a leading cause of mortality and morbidity in the United States. About 20% of the stroke is hemorrhagic and about 50% of these is due to aneurysmal subarachnoid hemorrhage. …”
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Progress of the Target Selection and Localization of Repetitive Transcranial Magnetic Stimulation to Improve Upper Limb Function after Stroke by LIU Canhuan, SHEN Ying, DAI Wenjun, GUO Chuan, CHENG Yihui, ZHU Yi, WANG Tong

“…Stroke is a common cerebrovascular disease with high morbidity, mortality, disability, and recurrence imposing significant social and economic burdens. …”
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