Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study by Lorena González, Carolina Gonzalez-Riano, Pablo Fernández-García, Rubén Cereijo, Aina Valls, Andrea Soria-Gondek, Nativitat Real, Belén Requena, Joan Bel-Comos, Patricia Corrales, David Jiménez-Pavón, Coral Barbas, Francesc Villarroya, David Sánchez-Infantes, Marta Murillo

“…Abstract Recombinant human growth hormone (rhGH) therapy is the primary treatment for children born small for gestational age (SGA) who fail to show spontaneous catch-up growth by two or four years. …”
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Immunohistochemical Studies of Age-Related Changes in Cell Proliferation and Angiogenesis during the Healing of Acetic Acid-Induced Gastric Ulcers in Rats by A. Folorunsho Ajayi, S. Babafemi Olaleye

“…Male Wistar rats (aged 3, 6, 12, and 18 months) divided into four groups, according to their ages, formed the experimental animals. …”
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A Long-Term Study of Aerobic Performance in Elite Cross-Country Skiers: How Age and Sex Influence Career Development by Elias Bucher, Jon P. Wehrlin, Grégoire P. Millet, Thomas Steiner

“…Males had a higher baseline VO2max at age 18 (70.8 vs. 58.2 mL/kg/min, 21.6% difference), but the rate of change with age was not significantly different between the sexes (p=0.259). …”
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The association of physical activity and carotid intima-media-thickness in adolescents—data of the prospective early vascular ageing-tyrol cohort study by Bernhard Winder, Bernhard Winder, Bernhard Winder, Sophia J. Kiechl, Sophia J. Kiechl, Benoît Bernar, Benoît Bernar, Nina Gande, Anna Staudt, Anna K. Stock, Anna K. Stock, Christoph Hochmayr, Ralf Geiger, Andrea Griesmacher, Stefan Kiechl, Stefan Kiechl, Ursula Kiechl-Kohlendorfer, Michael Knoflach, Michael Knoflach, the Early Vascular Ageing (EVA)-Tyrol Study Group, Carmen Reiter, Christina Schreiner Julia Klingenschmid, Julia Marxer, Martina Kothmayer, Maximilian Pircher, Manuela Bock-Bartl, Mandy Asare, Maximilian Bohl, Raimund Pechlaner

“…Our aim was to further investigate this unexpected association with two different measurement methods of PA and two established markers for Early Vascular Ageing: cIMT and carotid-femoral pulse-wave velocity (cfPWV).MethodsThe community-based Early Vascular Ageing-Tyrol cohort study included adolescents in western Austria and northern Italy. …”
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Safe Implementation of Treatments in Stroke: a study on intravenous thrombolysis in patients over 80 years of age with acute ischaemic stroke by Manju Krishnan, Danilo Toni, Niaz Ahmed, Anand Dixit, Ana Paiva Nunes, Marius Matusevicius, Jose Egido, Letizia Concari, Monica Reggiani, Alain Pagès, Thierry Danays

“…Objectives To investigate the safety and efficacy outcomes of intravenous thrombolysis (IVT) in patients aged >80 years with acute ischaemic stroke (AIS) after IVT was approved in this patient population in several European and non-European countries during 2018–2019.Design This is an observational registry study using prospectively collected data from the Safe Implementation of Treatment in Stroke (SITS) registry. …”
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Building an Index System for Evaluating the Motor Health of Preschool-aged Children from the Perspective of Disciplinary Intersections: A Delphi Study by Dongxu Du, Chairat Choosakul

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A novel nomogram for predicting mortality risk in young and middle-aged patients undergoing maintenance hemodialysis: a retrospective study by Lei Sun, Lei Sun, Yue Zhang, Yue Zhang, Xinliang Zuo, Xinliang Zuo, Yongmei Liu

“…This research seeks to explore the critical determinants impacting mortality risk in young and middle-aged MHD patients and to construct a prediction model accordingly.MethodsThis study involved 127 young and middle-aged patients undergoing MHD in the Blood Purification Center of Chaohu Hospital of Anhui Medical University from January 2019 to January 2022. …”
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The Association Between Internet Addiction and the Risk of Suicide Attempts in Chinese Adolescents Aged 11-17 Years: Prospective Cohort Study by Sihong Li, Xingyue Jin, Lintong Song, Tianqing Fan, Yanmei Shen, Jiansong Zhou

“…ObjectiveThis study aimed to conduct a prospective cohort study to examine whether higher severity of pathological internet use was associated with an increased risk of suicide attempts among Chinese adolescents. …”
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Central nervous system (CNS) medications and polypharmacy in later life: cross-sectional analysis of the English Longitudinal Study of Ageing (ELSA) by Natasha Slater, Simon White, Martin Frisher

“…Furthermore, this paper aims to determine whether polypharmacy and other factors, previously found to be associated with overall polypharmacy, are associated with the most common CNS drug classes.Design Cross-sectional study.Setting English Longitudinal Study of Ageing (wave 6).Participants 7730 participants (≥50 years).Main outcome measures Adjusted Odds Ratios (OR) and 95% confidence intervals (CI) for CNS drug classes.Results 31% of the sample were currently taking ≥5 medications (polypharmacy), of whom 58% (n=1362/2356) were taking CNS medicines as part of their regimen. …”
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Tongue Muscle Training App for Middle-Aged and Older Adults Incorporating Flow-Based Gameplay: Design and Feasibility Pilot Study by Kuan-Chu Su, Ko-Chiu Wu, Kuei-Ru Chou, Chia-Hsu Huang

“…This pilot study used an image recognition system to detect the tongue movements of 32 healthy middle-aged and older adults (7 males, 21.9%; 25 females, 78.1%) during 3 game training tasks, each requiring different reaction speeds. …”
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Labour and Neonatal Outcome in Small for Gestational Age Babies Delivered Beyond 36+0 Weeks: A Retrospective Cohort Study by K. E. Boers, J. A. M. van der Post, Ben W. J. Mol, J. M. M. van Lith, S. A. Scherjon

“…Objective. Small for gestational age (SGA) is associated with increased neonatal morbidity and mortality. …”
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Association of age-related macular degeneration on fracture risks among osteoporosis population: a nationwide population-based cohort study by Bing-Yu Chen, Chi Chin Sun, Ting-Shuo Huang, Tsai-Sheng Fu, Chia-Yi Lee, Fang-Ping Chen

“…This study was conducted to explore the relationship between AMD and incident fractures in patients with osteoporosis (OS).Design Retrospective analysis of Taiwan’s National Health Insurance Research Database (NHIRD).Setting A multicenter study conducted in Taiwan.Participants and controls The current study used the NHIRD in Taiwan between 1996 and 2011. …”
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Emotional and physical experiences of people with neovascular age-related macular degeneration during the injection process in Germany: a qualitative study by Oliver Zeitz, Martina Breuning, Christine Holmberg, Christian Wolfram, Anne Thier

“…Objectives In order to better understand the continued barriers to the provision of vascular endothelial inhibitor therapy, this study aims to investigate patients’ experiences with neovascular age-related macular degeneration (nvAMD) in Germany during the injection process and how they deal with it.Design and participants This analysis is part of the qualitative arm of a wider mixed-methods study. …”
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Predictors of anemia among infants at the age of one year attending health centers in the West Bank/Palestine: a retrospective study by Malakeh Z. Malak, Anas Shehadeh, Ahmad Ayed, Eman Alshawish

“…Abstract Background Anemia is a major problem among infants aged under 1 year. There are limited studies in Palestine about anemia among infants. …”
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Joint association of systemic immune-inflammation index and phenotypic age acceleration with chronic respiratory disease: a cross-sectional study by Yuan Zhan, Ruonan Yang, Jie Feng, Genlong Bai, Xiangyun Shi, Jiaheng Zhang, Jingbo Zhang

“…Conclusion This study confirmed the coexposure effect and mutual mediation between SII and PhenoAgeAccel on CRD. …”
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Associations between Age-Related Changes in the Core Vestibular Projection Pathway and Balance Ability: A Diffusion Tensor Imaging Study by Sang Seok Yeo, Jung Won Kwon, In Hee Cho

“…We investigated the changes of the vestibulospinal tract (VST) and parietoinsular vestibular cortex (PIVC) using diffusion tensor imaging (DTI) and relation to balance between old and young healthy adults. Methods. This study recruited eleven old adults (6 males, 5 females; mean age 63.36±4.25 years) and 12 young adults (7 males, 5 females; mean age 28.42±4.40 years). …”
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Social Media, Conspiracy Beliefs, and COVID-19 Vaccines: A Survey Study of Emerging and Middle-Aged Adults in the United States by Gillianne R. Nugent, Dina Anselmi, Brian N. Chin

“…This study examined the connections between social media use and behaviors, COVID-19 vaccine conspiracy beliefs, and COVID-19 vaccine uptake in 809 emerging and middle-aged adults. …”
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A Case Study Assessing the Auditory and Speech Development of Four Children Implanted with Cochlear Implants by the Chronological Age of 12 Months by Birgit May-Mederake, Wafaa Shehata-Dieler

“…Four children who received their first CI under 12 months of age were included in this study. Effects on auditory development were determined using the German LittlEARS Auditory Questionnaire, closed- and open-set monosyllabic word tests, aided free-field, the Mainzer and Göttinger speech discrimination tests, Monosyllabic-Trochee-Polysyllabic (MTP), and Listening Progress Profile (LiP). …”
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Reliability of radiomics features as imaging biomarkers for evaluating brain aging: A study based on myelin protein and diffusion tensor imaging by Yuting Yan, Mengmeng Hu, Xiaodong He, Yuyun Xu, Xiaojun Sun, Jiaxuan Peng, Fanfan Zhao, Yuan Shao

“…Therefore, the objective of this study was to obtain the most relevant radiomics features with the aging changes of myelin proteins and compare their diagnostic performances with the diffusion tensor imaging (DTI) parameters to identify the reliability of these features as imaging biomarkers for assessing brain aging. …”
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Real-world efficacy and safety of dupilumab in children with atopic dermatitis under 6 years of age: a retrospective multicentric study by Filip Rob, Blanka Pinkova, Kristyna Sokolova, Jana Kopuleta, Zuzana Jiraskova Zakostelska, Jana Cadova

“…In this multicentric real-world observational retrospective study, we evaluated the efficacy and safety of dupilumab for atopic dermatitis in children <6 years of age who underwent a minimum of 16 weeks of therapy. …”
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