Prediction of outpatient rehabilitation patient preferences and optimization of graded diagnosis and treatment based on XGBoost machine learning algorithm by Xuehui Fan, Ruixue Ye, Yan Gao, Kaiwen Xue, Zeyu Zhang, Jing Xu, Jingpu Zhao, Jun Feng, Yulong Wang

“…Driven by chronic diseases and an aging population, there is a need to enhance the efficiency and resource allocation of outpatient facilities. …”
Get full text

Post-extrasystolic variation of ST segment and T wave as a mortality risk predictor after myocardial infarction by Ralf J. Dirschinger, Ralf J. Dirschinger, Alexander Müller, Petra Barthel, Alexander Steger, Michael Dommasch, Axel Bauer, Karl-Ludwig Laugwitz, Georg Schmidt, Daniel Sinnecker, Daniel Sinnecker

“…Kaplan-Meier curves and univariable/multivariable Cox proportional hazards models were used to study mortality prediction by PEST. The findings were validated in an independent cohort of 1.788 general population subjects aged 60 years or older.ResultsThe area under the ROC curve for PEST was 0.72, with an optimum cutoff at ≤ −6.69 mV2. …”
Get full text

Associations of HLA-G 3’UTR polymorphisms and increased HLA-G expression with gastric cancer susceptibility and prognosis by Ines Zemni, Daria Bortolotti, Sabrine Dhouioui, Sana Baroudi, Malek Ferjani, Inès Nasri, Yosr Zenzri, Md Ataur Rahman, Abdel Halim Harrath, Roberta Rizzo, Nadia Boujelbene, Inès Zidi

“…The aim of the current study was to examine the relationship between Human leukocyte antigen (HLA)-G 3’UTR polymorphisms and the expression of HLA-G in both tumor tissues and plasma samples from patients with GC in the Tunisian population. …”
Get full text

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care dataResearch in context by Olivia Murrin, Ninon Mounier, Bethany Voller, Linus Tata, Carlos Gallego-Moll, Albert Roso-Llorach, Lucía A. Carrasco-Ribelles, Chris Fox, Louise M. Allan, Ruby M. Woodward, Xiaoran Liang, Jose M. Valderas, Sara M. Khalid, Frank Dudbridge, Sally E. Lamb, Mary Mancini, Leon Farmer, Kate Boddy, Jack Bowden, David Melzer, Timothy M. Frayling, Jane A.H. Masoli, Luke C. Pilling, Concepción Violán, João Delgado

“…Summary: Background: Multimorbidity, the presence of two or more conditions in one person, is common but studies are often limited to observational data and single datasets. …”
Get full text

The effect of the fenugreek hydrolyzed protein on lipid profile in patients with mild-to-moderate hypercholesterolemia: A confirmatory triple-blind randomized-controlled clinical t... by Mahdi Badiee Gavarti, Ali Askari, Hamidreza Roohafza, Mozhde Askari, Zahra Teimouri Jervekani, Shima Kaveh, Mohammad Kermanialghoraishi, Alireza Sadeghimahoonak, Masoumeh Sadeghi

“…Methods: This study is a confirmatory, triple-blind, two-group parallel, randomized controlled trial, phase 3 conducted on patients aged 18–65 years with mild-to-moderate hypercholesterolemia and low risk for cardiovascular disease. …”
Get full text

Effects of the MyBFF@school obesity intervention program with nutrition education intervention on nutrition knowledge and attitude of secondary schoolchildren: a cluster randomized... by Rusidah Selamat, Junidah Raib, Nur Azlina Abdul Aziz, Norlida Zulkafly, Ainan Nasrina Ismail, W Nurul Ashikin W Mohamad, Ainol Aizuddin Zulkiply, Muhammad Yazid Jalaludin, Fuziah Md. Zain, Zahari Ishak, Abqariyah Yahya, Abdul Halim Mokhtar

“…Therefore, to effectively impart the nutrition knowledge and change their nutrition attitude requires an in-depth study and multi-pronged and customized approach. …”
Get full text

Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus by Fátima Cano-Cano, Almudena Lara-Barea, Álvaro Javier Cruz-Gómez, Francisco Martín-Loro, Laura Gómez-Jaramillo, María Carmen González-Montelongo, María Mar Roca-Rodríguez, Lucía Beltrán-Camacho, Lucía Forero, Javier J. González-Rosa, Mª Carmen Durán-Ruiz, Ana I. Arroba, Manuel Aguilar-Diosdado

“…Abstract Background Interest in the study of type 1 diabetes mellitus (T1DM) and multiple sclerosis (MS) has increased because of their significant negative impact on the patient quality of life and the profound implications for the health care system. …”
Get full text

Maternal Satisfaction towards Childhood Immunization Service and Its Associated Factors in Wadla District, North Wollo, Ethiopia, 2019 by Fisha Alebel GebreEyesus, Nega Tezera Assimamaw, Netsanet Tsegaye GebereEgziabher, Bisrat Zeleke Shiferaw

“…Objective. The aim of this study was to assess maternal satisfaction towards childhood immunization service and its associated factors among mothers’ having children aged less than 1 year in Wadla district, North Wollo, Ethiopia, 2019. …”
Get full text

Effects of dribbling restrictions in small-sided games on aerobic and anaerobic fitness in youth basketball players by Mingbang Li, Liang Tan, Hong Wu, Jianwei Wu

“…However, the long-term effects on physical adaptations remain unexplored. This experimental study aimed to compare the impact of free-play SSGs (freeD) and limited-dribbling SSGs (limitedD) in SSGs on the aerobic and anaerobic adaptations of youth basketball players.MethodsForty-five youth basketball players (aged 15.7 ± 0.6 years, with 4.2 ± 0.7 years of experience) were randomly assigned to two experimental groups (freeD and limitedD) and a control group (not exposed to SSG interventions). …”
Get full text

qBiCo: a method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elements by Faidra Karkala, Roy B. Simons, Floor Claessens, Vivian Kalamara, Manfred Kayser, Athina Vidaki

“…Abstract Background Human DNA methylation profiling offers great promises in various biomedical applications, including ageing, cancer and even forensics. So far, most DNA methylation techniques are based on a chemical process called sodium bisulfite conversion, which specifically converts non-methylated cytosines into uracils. …”
Get full text

Severe Hepatotoxicity in Mushroom Poisoning by Lepiota brunneoincarnata from Complete Recovery to Liver Transplantation: A Case Series with Review on Liver Function Tests and Liver... by Mohammad Hossein Anbardar, Neda Soleimani, Kourosh Kazemi, Zahra Jafarpour, Mahsa Hasani, Sahand Mohammadzadeh, Parnia Torfehnezhad, Sedighe Jafarian, Mahsa Farhadi, Mina Salari Sardari

“…The patients were between the ages of 18 and 67 years, composed of ten females and eight males. …”
Get full text

Influence of symptoms of attention deficit hyperactivity disorder on emotional behavioral problems： parallel mediating effect of different dimensions of executive function by XUE Yiyun, OU Zixin, HONG Danping, DANG Caiping, ZHU Zhihang, CHENG Daomeng, HU Yingzi, LI Guoquan, YANG Chanjuan, YIN Weizhen

“…Methods A total of 102 children with ADHD aged 6-12 years old who met the Diagnostic and Statistical Manual of Mental Disorders 5th edition （DSM-5） criteria were selected as the study subjects. …”
Get full text

Using Dose-Effect Relationship for Optimising Systemic Corticosteroid Dosage in Treatment of Inflammatory Bowel Diseases by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…Estimation of an optimal corticosteroid (CS, prednisone) dosage for the remission induction in patients with ulcerative colitis (UC) and Crohn’s disease (CD) based on the construction of a dose-effect relationship during the first and second courses of therapy.Materials and methods. The study included 86 patients with moderate to severe active disease (61 with UC and 25 with CD) aged 18 to 65 years. …”
Get full text

Assessment of Reproductive Performance and Husbandry Practices of Horro and Crossbred Cattle Under Smallholder in Sibu Sire District of East Wollega Zone, Oromia, Ethiopia by Abriham Kebede Deresa, Jiregna Dugassa Kitessa, Yobsan Tamiru Terefa

“…Result Seventy‐nine percent of animal owners involved were men, ages between 30 and 60. Their education was as follows: 26% were illiterate, 67% in primary school and 7% in secondary school. …”
Get full text

Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease. by Magdaléna Neřoldová, Elżbieta Ciara, Janka Slatinská, Soňa Fraňková, Petra Lišková, Radana Kotalová, Janka Globinovská, Markéta Šafaříková, Lucie Pfeiferová, Hana Zůnová, Lenka Mrázová, Viktor Stránecký, Alena Vrbacká, Ondřej Fabián, Eva Sticová, Daniela Skanderová, Jan Šperl, Marta Kalousová, Tomáš Zima, Milan Macek, Joanna Pawlowska, A S Knisely, Stanislav Kmoch, Milan Jirsa

“…(Lys56Thr) born to first cousins, had liver disease, interpreted on biopsy aged 4y as glycogen storage disease, followed by adult-onset nephronophthisis at 25y. …”
Get full text

Therapeutic Potential of Ginger Ethanolic Extract, Ginger-Loaded Chitosan ‎Nanoparticles, and Chitosan Nanoparticles in Induced Type 2 Diabetes Mellitus in Dogss in Induced Type 2... by Rasema M Hameed, Alaa K Mahmood

“…Twenty adult local breed mongrel dogs of both sexes, aged 7 to 13 months, with an average body weight of 10.4±0.76 kg, were included. …”
Get full text

THE RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH ADRENAL TUMORS by A. A. Kostin, N. V. Vorobyev, A. O. Tolkachev, A. G. Muradyan, S. V. Popov

“…According to the routine morphological studies, 24 (43,6%) patients the tumor were benign, the remaining 31 (56,4%) – malignant.Results. …”
Get full text

Effects of tropicamide and compound tropicamide eye drops on ocular biological parameters and choroid thickness in children by Mengyue Xu, Na Li, Yan Liu, Yaru Chen, Shuping Xie, Jianfeng Wang

“…Abstract Objectives To evaluate the effects of short-acting cycloplegic agents, tropicamide and compound tropicamide, on ocular biological parameters and choroid thickness. Methods In this study, seventy pediatric subjects aged 6 to 13 years were randomly assigned to two groups: the tropicamide group and compound tropicamide group. …”
Get full text

Long-term trends and patterns in ultra-processed food consumption among Korean adults from 1998 to 2022 by Hyeseung Lee, Yesol Yim, Yerin Cho, Jiyeon Oh, Soeun Kim, Yejun Son, Hyesu Jo, Seohyun Hong, Masoud Rahmati, Hanseul Cho, Jiyoung Hwang, Dong Keon Yon

“…Despite rising consumption due to Westernized diets in Asia, long-term studies targeting Asian adults are lacking. Thus, we analyzed ultra-processed food consumption trends among Korean adults from 1998 to 2022. …”
Get full text

Evaluating the Efficacy of a Serious Game to Deliver Health Education About Invasive Meningococcal Disease: Clustered Randomized Controlled Equivalence Trial by Lauren Bloomfield, Julie Boston, Martin Masek, Lesley Andrew, Donna Barwood, Amanda Devine

“…Serious games may be an alternative to face-to-face education, where complex health information may be delivered via self-directed gameplay. ObjectiveThis study aims to develop a serious game that can replace a face-to-face educator in a classroom setting to educate adolescents aged 12 years to 15 years. …”
Get full text