Morphometric parameters of pelvic lymph nodes in experimental metastatic prostate cancer by V. V. Astashov, N. G. Kulchenko

“…The study included 30 male mice aged 3 months. All animals (n = 30) were divided into 2 groups. …”
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Feasibility and psychometric quality of smartphone administered cognitive ecological momentary assessments in women with metastatic breast cancer by Ashley M Henneghan, Emily W Paolillo, Kathleen M Van Dyk, Oscar Y Franco-Rocha, Soyeong Bang, Rebecca Tasker, Tara Kaufmann, Darren Haywood, Nicolas H Hart, Raeanne C Moore

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Optimization of a microarray for fission yeast by Dong-Uk Kim, Minho Lee, Sangjo Han, Miyoung Nam, Sol Lee, Jaewoong Lee, Jihye Woo, Dongsup Kim, Kwang-Lae Hoe

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The role of inflammatory system genes in individual differences in nonverbal intelligence by R. F. Enikeeva, A. V. Kazantseva, Yu. D. Davydova, R. N. Mustafin, Z. R. Takhirova, S. B. Malykh, Y. V. Kovas, E. K. Khusnutdinova

“…Therefore, the genes encoding pro- and antiinf lammatory cytokines are prospective candidate genes in the study of nonverbal intelligence. Within the framework of the present study, we conducted the association analysis of six SNPs in the genes that encode proteins involved in inf lammatory response regulation in the central nervous system (CRP rs3093077, IL1А rs1800587, IL1B rs16944, TNF/ LTA rs1041981, rs1800629, and P2RX7 rs2230912), with nonverbal intelligence in mentally healthy young adults aged 18– 25 years without cognitive decline with inclusion of sex, ethnicity and the presence of the “risky” APOE ε4 allele as covariates. …”
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Altered brain functional network connectivity and topology in type 2 diabetes mellitus by Weiwei Ni, Weiyin Vivian Liu, Mingrui Li, Shouchao Wei, Xuanzi Xu, Shutong Huang, Lanhui Zhu, Jieru Wang, Fengling Wen, Hailing Zhou

“…IntroductionType 2 diabetes mellitus (T2DM) accelerates brain aging and disrupts brain functional network connectivity, though the specific mechanisms remain unclear. …”
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Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised... by Luregn J Schlapbach, Barbara Brotschi, Kristen S Gibbons, Florian Zapf, Rebeca Mozun, Daphné Chopard, Philipp Baumann, Anika Adam, Vera Jaeggi, Beat Bangerter, Juerg Burren

“…Study results will be disseminated through publication in a peer-reviewed journal and other media like podcasts.Trial registration number NCT05843123.…”
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NLRP3 inflammasome-modulated angiogenic function of EPC via PI3K/ Akt/mTOR pathway in diabetic myocardial infarction by Jia-Peng Li, Shu Qiu, Guang-Jie Tai, Yi-Ming Liu, Wei Wei, Meng-Meng Fu, Pan-Qi Fang, Joseph Nicolao Otieno, Tungalag Battulga, Xiao-Xue Li, Ming Xu

“…Chip and Luciferase assay revealed CEBPB regulated the transcriptional expression of Nlrp3 as a transcription factor in EPC stimulated by high glucose (HG) or advanced glycation end products (AGEs). CO-IP results suggested that USP14 selectively suppressed NLRP3 degradation. …”
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Chronic lung lesions in COVID-19 survivors: predictive clinical model by Paulo A Lotufo, Juliana C Ferreira, Eloisa Bonfa, Anna S Levin, Rodrigo Caruso Chate, Marta Imamura, Esper G Kallas, Roger Chammas, Thais Mauad, Izabel Marcilio, Nelson Gouveia, Ricardo Nitrini, José Eduardo Krieger, Marcio Valente Yamada Sawamura, Michelle Louvaes Garcia, Cristiano Gomes, Guilherme Fonseca, Jorge Hallak, Luis Yu, Marcio Mancini, Maria Elizabeth Rossi, Thiago Avelino-Silva, Edivaldo M Utiyama, Aluisio C Segurado, Beatriz Perondi, Anna Miethke-Morais, Amanda C Montal, Leila Harima, Marjorie F Silva, Marcelo C Rocha, Maria Amélia de Jesus, Carolina Carmo, Clarice Tanaka, Julio F M Marchini, Thaís Guimarães, Ester Sabino, Carlos Roberto Ribeiro Carvalho, Celina Almeida Lamas, Diego Armando Cardona Cardenas, Daniel Mario Lima, Paula Gobi Scudeller, João Marcos Salge, Cesar Higa Nomura, Marco Antonio Gutierrez, Adriana L Araújo, Bruno F Guedes, Carolina S Lázari, Cassiano C Antonio, Claudia C Leite, Emmanuel A Burdmann, Euripedes C Miguel, Fabio R Pinna, Fabiane Y O Kawano, Geraldo F Busatto, Giovanni G Cerri, Heraldo P Souza, Izabel C Rios, Larissa S Oliveira, Linamara R Batisttella, Luiz Henrique M Castro, Marcello M C Magri, Maria Cassia J M Corrêa, Maria Cristina P B Francisco, Maura S Oliveira, Orestes V Forlenza, Ricardo F Bento, Rodolfo F Damiano, Rossana P Francisco, Solange R G Fusco, Tarcisio E P Barros-Filho, Wilson J Filho

“…Objective This study aimed to propose a simple, accessible and low-cost predictive clinical model to detect lung lesions due to COVID-19 infection.Design This prospective cohort study included COVID-19 survivors hospitalised between 30 March 2020 and 31 August 2020 followed-up 6 months after hospital discharge. …”
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Development of an individualized dementia risk prediction model using deep learning survival analysis incorporating genetic and environmental factors by Shiqi Yuan, Qing Liu, Xiaxuan Huang, Shanyuan Tan, Zihong Bai, Juan Yu, Fazhen Lei, Huan Le, Qingqing Ye, Xiaoxue Peng, Juying Yang, Yitong Ling, Jun Lyu

“…To facilitate further research, the team deployed the DeepSurv dementia prediction model on AliCloud servers and designated it as the UKB-DementiaPre Tool. Conclusion This study successfully developed and validated the DeepSurv dementia prediction model for individuals aged 60 years and above, integrating both genetic and clinical data. …”
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The role of the KIBRA and APOE genes in developing spatial abilities in humans by A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, R. N. Mustafin, Z. R. Takhirova, S. B. Malykh, M. M. Lobaskova, T. N. Tikhomirova, E. K. Khusnutdinova

“…Considering a significant role of genetic and environmental components in cognitive functioning, the present study aimed to estimate the main effect of NGF (rs6330), NRXN1 (rs1045881, rs4971648), KIBRA (rs17070145), NRG1 (rs6994992), BDNF (rs6265), GRIN2B (rs3764030), APOE (rs7412, rs429358), and SNAP25 (rs363050) gene polymorphisms and to assess the effect of gene-environment interactions on individual differences in spatial ability in individuals without cognitive decline aged 18–25 years (N = 1011, 80 % women). …”
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Polymorphic variants of the dopamine receptor gene <i>DRD2</i> (rs6277, rs1800497) in adolescents with problematic video game use by S. Yu. Tereshchenko, K. V. Afonicheva, I. V. Marchenko, M. V. Shubina, M. V. Smolnikova

“…An increasing incidence of addictive video gaming, as well as the overuse of the Internet, among the young population makes the current study of susceptibility factors, including the genetic component, relevant. …”
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Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led tel... by Jeanne Cho, Michael Hill, Corita R Grudzen, Deborah J Shim, Abigail M Schmucker, Keith S Goldfeld, Lauren Southerland, Jeffrey M Caterino, Marie-Carmelle Elie, Robert Swor, Susan E Cohen, Arum Kim, Joseph Lowy, Jennifer S Scherer, Nancy E Bael, Ellin Gafford, Joshua Lakin, Paige Barker, Angela Chmielewski, Jennifer Kapo, Audrey Tan, Rebecca Yamarik, Susan Salz, Stephen Ryan, Anne Kim, Isabel Castro, Amelia Hargrove, Laura Stuecher, Nora Daut, Juanita Booker-Vaughns, Garrett K Chan, J Nicholas Dionne-odom, Patrick Dunn, Robert Galvin, Ernest A Hopkins III, Margaret M Maguire, Neha Reddy Pidatala, Dawn Rosini, Sally Welsh, Karen Jubanyik, Ada L Rubin, Kei Ouchi, Rebecca Murray, Nicole Tang, Marie Bakitas, Abraham Brody, Caroline Blaum, Mara Flannery, Richard Tamirian, Pamela Marsack, Jennifer Bonito, Romilla Batra, Donna C Sadasivan, Eric David Isaacs, Constance L Kizzie-Gillett, William K Vaughan, Pluscedia G Williams, Angela Young-Brinn

“…We will enrol 1350 patients aged 50+ years and 675 of their caregivers across nine EDs. …”
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The Influence of Depression, Anxiety, and Stress on Ageism Among Undergraduates: Mediating Roles of Life Satisfaction, Gratitude, and Prosociality by Chen S, Wan Z

“…It then examines the predictive effects of depression, anxiety, and stress (DAS) on ageism, accounting for these socio-demographic factors. Finally, the study explores how DAS influences ageism both directly and indirectly through life satisfaction, gratitude, and prosociality.Design and Settings: A cross-sectional study conducted at 11 higher education institutions in Jiangxi, China.Participants: A total of 1,213 undergraduates participated in the study between July and August 2024. …”
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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context by Podjanee Jittamala, Simon Boyd, William H.K. Schilling, James A. Watson, Thundon Ngamprasertchai, Tanaya Siripoon, Viravarn Luvira, Elizabeth M. Batty, Phrutsamon Wongnak, Lisia M. Esper, Pedro J. Almeida, Cintia Cruz, Fernando R. Ascencao, Renato S. Aguiar, Najia K. Ghanchi, James J. Callery, Shivani Singh, Varaporn Kruabkontho, Thatsanun Ngernseng, Jaruwan Tubprasert, Wanassanan Madmanee, Kanokon Suwannasin, Amornrat Promsongsil, Borimas Hanboonkunupakarn, Kittiyod Poovorawan, Manus Potaporn, Attasit Srisubat, Bootsakorn Loharjun, Walter R.J. Taylor, Farah Qamar, Abdul Momin Kazi, M. Asim Beg, Danoy Chommanam, Sisouphanh Vidhamaly, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Arjen M. Dondorp, Nicholas P.J. Day, Mauro M. Teixeira, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Nicholas J. White

“…Patients were assigned using block randomisation to one of eleven treatment arms including oral fluoxetine (40 mg/day for 7 days), or no study drug. Uniform randomisation ratios were applied across the active treatment groups while the no study drug group comprised ≥20% of patients at all times. …”
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Evaluation of Health Science Students&rsquo; Knowledge, Attitudes, and Practices Toward Artificial Intelligence in Northern Saudi Arabia: Implications for Curriculum Refinement and... by ALruwail BF, Alshalan AM, Thirunavukkarasu A, Alibrahim A, Alenezi AM, Aldhuwayhi TZA

“…We evaluated northern Saudi health science students’ knowledge, attitude, practice, and associated factors toward AI.Participants and Methods: The present cross-sectional study was conducted among 384 health science students aged 18 years and above from Jouf University, KSA. …”
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Incidence and predictors of seizure-related injuries among epileptic patients undergoing follow-up treatment at public hospitals in Central Ethiopia by Selamawit Wondale Begizew, Bethelhem Birhanu Muluneh, Taye Mezgebu Ashine, Asnakech Zekiwos Heliso, Getachew Ossabo Babore, Elias Ezo Ereta, Sentayehu Admasu Saliya, Awoke Girma Hailu, Elias Nigusu Abdisa

“…The study included epileptic patients aged ≥ 18 years who had not experienced any previous injury during follow-up treatment from January 1st, 2023, to December 31st, 2023. …”
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Evaluation of Lyso-Gb1 as a biomarker for Gaucher disease treatment outcomes using data from the Gaucher Outcome Survey by Ari Zimran, Shoshana Revel-Vilk, Tama Dinur, Majdolen Istaiti, Jaco Botha, Elena Lukina, Pilar Giraldo, Patrick Deegan, Stephan vom Dahl

“…Methods Data for patients aged ≥ 18 years with a confirmed diagnosis of GD and at least two lyso-Gb1 assessments were analyzed retrospectively. …”
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The appearance of scalp high‐frequency oscillations is associated with poor seizure control in pediatric epilepsy patients by Keisuke Maeda, Nami Hosoda, Himari Tsuboi, Honoka Naito, Chiaki Kudo, Junichi Fukumoto, Shiho Fujita, Naohiro Ichino, Keisuke Osakabe, Keiko Sugimoto, Shunta Yamaguchi, Naoko Ishihara

“…Methods A total of 72 epilepsy patients (aged 0–18 years, 39 males) with good and poor seizure control with ASMs participated in this study. …”
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Nomophobia, phubbing, and deficient sleep patterns in college students by Margit Julia Guerra Ayala, Olga María Alegre de la Rosa, Maria Amparo del Pilar Chambi Catacora, Elizabeth Vargas Onofre, Edith Cari Checa, Débora Díaz Flores

“…The sample consisted of 533 students from a private university in Peru, aged 18 to 24, selected through non-probabilistic sampling. …”
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Orthopedic Frailty Score and adverse outcomes in patients with surgically managed isolated traumatic spinal injury by Yang Cao, Shahin Mohseni, Babak Sarani, Frank Hildebrand, Ahmad Mohammad Ismail, Maximilian Peter Forssten, Parker Chang, Marcelo A F Ribeiro

“…Background With an aging global population, the prevalence of frailty in patients with traumatic spinal injury (TSI) is steadily increasing. …”
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