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4001
Effects of Single Nucleotide Polymorphism Marker Density on Haplotype Block Partition
Published 2016-12-01“…We used several experimental datasets obtained by sampling subsets of single nucleotide polymorphism (SNP) markers of chromosome 22 region in the 1000 Genomes Project data and also the HapMap phase 3 data to compare the results of haplotype block partitions by five methods. …”
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4002
Mechanistic insight of curcumin: a potential pharmacological candidate for epilepsy
Published 2025-01-01“…In the present review, we reviewed curcumin’s modulatory effects on potential biomarkers involved in epileptogenesis including dendritic cells, T cell subsets, cytokines, chemokines, apoptosis mediators, antioxidant mechanisms, and cognition impairment. …”
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4003
The identification of a SARs-CoV2 S2 protein derived peptide with super-antigen-like stimulatory properties on T-cells
Published 2025-01-01“…Like SEB and SEH derived peptides, P3 stimulated 25–40% of human CD4+ and CD8 + T-cells, increasing IFN-γ and granzyme B production. viSNE and SPADE profiling identified overlapping and distinct IFN-γ+ and GZMB+ subsets. The super-antigenic properties of P3 were further evident by its selective expansion of T-cells expressing specific TCR Vα and Vβ chain repertoires. …”
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4004
Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma
Published 2024-12-01“…Understanding the complex interactions between B cell subsets and the TME could lead to new strategies for enhancing the treatment and prognosis of HNSCC patients.…”
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4005
The Alteration and Clinical Significance of Th22/Th17/Th1 Cells in Patients with Chronic Myeloid Leukemia
Published 2015-01-01“…Bone marrow (BM) and peripheral blood (PB) were extracted from newly diagnosed (ND), chronic phase- (CP-) CML patients, and controls. Th subsets were examined by flow cytometry. Plasma IL-22, IL-17, and IFN-r concentrations were measured by ELISA. …”
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4006
Extensive Characterization of Mesenchymal Stem Cell Marker Expression on Freshly Isolated and In Vitro Expanded Human Adipose-Derived Stem Cells from Breast Cancer Patients
Published 2020-01-01“…Phenotypic characterization of heterogeneous cell subsets in stromal vascular fraction (SVF) isolated from fat tissues by flow cytometry was also limited to a combination of few molecules. …”
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4007
Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target
Published 2024-05-01“…The T cell compartment in the FL-PDLS preserves CD4 subsets (follicular helper, regulatory, and follicular regulatory), also encompassing the spectrum of activation/exhaustion phenotypes in CD4 and CD8 populations. …”
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4008
Clinical relevance and druggability of sole reciprocal kinase fusions: A large‐scale study
Published 2024-09-01“…Cross‐validation through RNA‐NGS and FISH authenticated the existence of functional kinase domains in subsets including ALK, ROS1, RET, and BRAF, which correlated with positive clinical responses to targeted kinase inhibitors (KIs). …”
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4009
珠海城区臭鼩身体大小和脏器指数的性别及季节差异
Published 2022-01-01“…小型哺乳动物的身体和脏器重是动物对环境适应的近似指标,可随环境条件的变化进行适应性调整。以珠海市城区环境中分布的臭鼩(<i>Suncus murinus</i>)为研究对象,2019年5月—2021年3月测定其身体大小及脏器指数的性别差异和季节动态,以深入理解其脏器对环境的生理适应机制。…”
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4010
Microscale search-based algorithm based on time-space transfer for automated test case generation
Published 2025-01-01“…In this paper, we present a microscale (small-size subsets of the decomposed decision set) search-based algorithm with time-space transfer (MISA-TST). …”
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4011
Feature selection enhances peptide binding predictions for TCR-specific interactions
Published 2025-01-01“…A broad range of physicochemical properties, including amino acid composition, dipeptide composition, and tripeptide features, were integrated into the machine learning-based feature selection framework to identify key properties contributing to binding affinity.ResultsOur analysis reveals that leveraging optimized feature subsets not only simplifies the model complexity but also enhances predictive performance, enabling more precise identification of TCR peptide interactions. …”
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4012
P53 and Expression of Immunological Markers May Identify Early Stage Thyroid Tumors
Published 2013-01-01“…ACIS-III system was used to evaluate p53 and immune cell markers including tumor-associated macrophages (TAM); CD68 and tumor-infiltrating lymphocytes (TIL) subsets such as CD3, CD4, CD8, and CD20 in 206 thyroid carcinomas, 105 benign nodules, and 18 normal tissues. …”
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4013
Local field potentials in a pre-motor region predict learned vocal sequences.
Published 2021-09-01“…Characterizations of this neural activity detail patterns of sequential bursting in small, carefully identified subsets of neurons in the HVC population. The dynamics of HVC are well described by these characterizations, but have not been verified beyond this scale of measurement. …”
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4014
Entre personnalisme et surréalisme : Albert Béguin, la critique littéraire et la question du suicide
Published 2012-09-01“…En mai 1950, Béguin succède à Mounier à la direction d’Esprit et s’attache à promouvoir une littérature qui ne se réduit pas à l’Hexagone. …”
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4015
Intracellular Cytokine Flow Cytometry to Differentiate between Active and Latent Tuberculosis through Assessment of Tuberculosis-specific Cytokines
Published 2024-12-01“…QFT, ICCFC, and lymphocyte subsets were tested. The diagnostic performance of the ICCFC in detecting LTBI and MTB in comparison with the QFT was analyzed. …”
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4016
Role of T Regulatory Cells and Myeloid-Derived Suppressor Cells in COVID-19
Published 2022-01-01“…In viral infections, MDSC levels are highly increased, and they have the potential to suppress T cell proliferation and reduce viral clearance. Some subsets of MDSCs are expanded in the blood of COVID-19 patients; however, there is a controversy whether this expansion has pathogenic or protective effects in COVID-19 patients. …”
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4017
High‐Efficiency Flexible GaAs/InGaAs Dual‐Junction Solar Cells Fabricated by Metallic Nanoparticle‐Based Wafer Bonding
Published 2025-02-01“…Herein, flexible GaAs/In0.53Ga0.47As dual‐junction solar cells with a large lattice mismatch of 3.7% between the subcells are fabricated using an indium‐tin‐oxide (ITO) nanoparticle‐based wafer bonding process. …”
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4018
Advantages of N-Type Hydrogenated Microcrystalline Silicon Oxide Films for Micromorph Silicon Solar Cells
Published 2013-01-01“…The enhancement of the open circuit voltage (Voc) was likely to be due to a reduction of reverse bias at subcell connection—n top/p bottom interface—and a better tunnel recombination junction contributed to the improvement in the fill factor (FF). …”
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4019
INOVAÇÃO TECNOLÓGICA E GESTÃO: a importância da Avaliação de Impactos Ambientais¹
Published 2014-03-01“…O intuito desse trabalho é investigar de que forma os pesquisadores da área agrícola estão percebendo os efeitos dessa tendência de submeter a inovação a modelos sofisticados de avaliação de impactos ambientais. …”
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4020
IL-33 Protects Mice against DSS-Induced Chronic Colitis by Increasing Both Regulatory B Cell and Regulatory T Cell Responses as Well as Decreasing Th17 Cell Response
Published 2018-01-01“…The production of cytokines was measured by ELISA. The T and B cell subsets were measured by flow cytometry. The expression of mRNA of transcription factors was measured by quantitative real-time PCR. …”
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