Effects of community family doctors-led intervention for self-management and medication adherence in type 2 diabetes mellitus patients: study protocol of a cluster randomised contr... by Yue Chen, Biqi Ren, Ningsheng Wang, Shuang Lei, Shuzhi Lin, Lianye Liu, Yufang Xiang, Bianling Feng

“…Introduction The management of diabetes has become a critical public health issue in China. The development of community-based type 2 diabetes management in China has not yet reached an ideal state, and the most suitable management methods for diabetic patients are still being explored. …”
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Person-centred eHealth intervention for patients on sick leave due to common mental disorders: study protocol of a randomised controlled trial and process evaluation (PROMISE) by Ingibjörg H Jonsdottir, Hanna Gyllensten, Lilas Ali, Andreas Fors, Karl Swedberg, Inger Ekman, Matilda Cederberg, Kristina Glise

“…Person-centred care (PCC) has previously shown positive effects on self-efficacy however this needs to be further investigated in relation to patients with CMDs and in an eHealth context.Methods and analysis This study is an open randomised controlled trial comparing a control group receiving standard care with an intervention group receiving standard care plus PCC by telephone and a digital platform. …”
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Explainable AI in Diagnostic Radiology for Neurological Disorders: A Systematic Review, and What Doctors Think About It by Yasir Hafeez, Khuhed Memon, Maged S. AL-Quraishi, Norashikin Yahya, Sami Elferik, Syed Saad Azhar Ali

“…Imagining techniques like magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) scans have been widely and very effectively employed by radiologists and neurologists for the differential diagnoses of neurological disorders for decades, yet no AI-powered systems to analyze such scans have been incorporated into the standard operating procedures of healthcare systems. …”
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Rationale and design for the thoracic Paravertebral Adjunctive Dexamethasone Palmitate Reducing chronic pain After cardiac surgery (PANDORA) trial: a parallel-group, double-blinded... by Jing Zhao, Hui Zhang, Ziyu Zheng, Baobao Gao, Lini Wang, Chong Lei, Hailong Dong, Taoyuan Zhang, Jiao Gao, Lihong Hou

“…The nature and intensity of pain will be evaluated with a Brief Pain Inventory Short Form (BPI-SF) questionnaire.Ethics and dissemination The trial was approved by the Ethics Committee of Xijing Hospital, the First Affiliated Hospital of Air Force Military Medical University (KY20232194-C-1). …”
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EXtending Omalizumab Treatment Intervals in patients with Chronic spontaneous urticaria (EXOTIC): protocol of a multicentre, randomised, open-label, non-inferiority trial by Alexander Egeberg, Ditte Georgina Zhang, Christian Vestergaard, Simon Francis Thomsen, Jennifer Astrup Sørensen, Misbah Noshela Ghazanfar, Zarqa Ali, Jacob Thyssen

“…Introduction Omalizumab, an anti-IgE monoclonal antibody, is effective in treating antihistamine-refractory chronic spontaneous urticaria (CSU). …”
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Factors affecting the implementation of guideline-based prophylactic antiemetic therapy for chemotherapy-induced nausea and vomiting in Japan: a protocol for a hospital-based quali... by Yosuke Uchitomi, Junko Saito, Maiko Fujimori, Taichi Shimazu, Ayako Okuyama, Sadamoto Zenda, Ayumu Matsuoka, Akiko Yaguchi-Saito, Yuki Kaji, Miyuki Odawara, Aki Otsuki

“…Introduction Chemotherapy-induced nausea and vomiting (CINV) decrease patients’ quality of life and negatively impact treatment outcomes. Although standard prophylactic antiemetic therapy for acute CINV recommended by guidelines is effective, poor guideline implementation is a worldwide problem. …”
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Gender-based Morphometric Analysis of the Human Orbital Aperture Profile using 3D Reconstruction Computed Tomography: A Cross-sectional Retrospective Study by Muhammad Omer Afzal Bhatti, Mujeeb Ur Rehman Parrey, Muhammad Ikram Ali, Allah Rakhyo Shoro, Abdulkrem Ahmed Alenazi, Rayan Alhumaidi Alruwaili

“…A statistically significant difference was found in right orbital width (p-value=0.011), left orbital area (p-value=0.04), and Interzygomatic Distance (IZD), with these measurements being higher in males compared to females (p-value=0.009). …”
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Medical Students’ Tobacco Consumption Status and Experiences with Smoke-free Law Violations in Enclosed Spaces in Türkiye and Northern Cyprus by Dilek Aslan, Pınar Ay, Kervin Raymond, Özen Aşut, Gulifeiya Abuduxike, Meltem Şengelen, Duygu Çekici, Füsun Yıldız, Emine Ünal Evren, Ali Fuat Kalyoncu, Elif Dağlı

“…RESULTS: Most participants were female (56.4%), with a mean age of 21.5±2.37 years. Nearly one in five students was a current tobacco user (19.9%). …”
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Surgical resection, radiotherapy and percutaneous thermal ablation for treatment of stage 1 non-small cell lung cancer: protocol for a systematic review and network meta-analysis by Arun Chockalingam, Menelaos Konstantinidis, Brandon Koo, John Timothy Moon, Andrew Tran, Sahar Nourouzpour, Emily Lawson, Kathleen Fox, Peiman Habibollahi, Bruno Odisio, Mohammed Loya, Ali Bassir, Nariman Nezami

“…For each outcome, given enough studies, we will conduct a network meta-analysis. Finally, we will use the Confidence in Network Meta-Analysis tool to assess quality of the evidence for each of the primary outcomes.Ethics and dissemination We aim to share our findings through high-impact peer review. …”
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Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost-effectiveness of Social Stories... by Dean McMillan, Victoria Allgar, Barry Wright, David Marshall, Shehzad Ali, Joy Adamson, Chris Williams, Elizabeth Littlewood, Dominic Trépel, Lisa Dyson, Hannah Ainsworth, Liz Cook, Lisa Hackney, Danielle Collingridge Moore, Rebecca Hargate, Anne McLaren, Jo Whitehead

“…All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. …”
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Effects of inulin-type fructans supplementation on cardiovascular disease risk factors: a protocol for a systematic review and meta-analysis of randomised controlled trials by Russell J de Souza, Lawrence Mbuagbaw, John L Sievenpiper, Dena Zeraatkar, Laura Banfield, Vanessa Ha, David J A Jenkins, Jhalok Ronjan Talukdar, Matthew Adam Cooper, Lyuba Lyutvyn, Rahim Ali, Rachel Bierbrier, Sabrina Janes, Pauline B Darling

“…Introduction This review aims to assess the effects of dietary supplementation with inulin-type fructans (ITF) compared with no supplementation on cardiovascular disease risk factors in adults and assess the quality of trial reporting using the Consolidated Standards of Reporting Trials (CONSORT) and CONSORT for abstract (CONSORT-A) checklists.Methods and analysis We will search randomised controlled trials (RCTs) in MEDLINE, EMBASE, CINAHL, Emcare, AMED and the Cochrane Database of Systematic Reviews from inception to 31 March 2022, without any language restrictions. …”
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Practices and preferences in the use of magnification among endodontists and restorative dentists: A multicentre study. by Azhar Iqbal, Mohmed Isaqali Karobari, Deepti Shrivastava, Kumar Chandan Srivastava, Bilal Arjumand, Hmoud Ali Algarni, Meshal Aber Alonazi, Muhsen Alnasser, Osama Khattak, Jamaluddin Syed, Reham Mohmad Attia, Asma Abubakar Rashed, Sherif El Sayed Sultan

“…<h4>Materials and methods</h4>A multicenter, cross-sectional study was ethically approved from the local committee of bioethics. …”
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Against utilitarianism in animal testing law by Eva Bernet Kempers

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Considering the fate of equestrian sports after the Olympics in Paris 2024 by Małgorzata Lubelska-Sazanów

“…This article aims to show the reality of animal welfare standards in modern equestrian sports, its pros, cons and the possible fate of these Olympic disciplines in the nearest future. …”
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Clinico-Epidemiological Profile of Children Orphaned due to AIDS Residing in Care Giving Institutions in Coastal South India by Rekha Thapar, Meher Singha, Nithin Kumar, Prasanna Mithra, Bhaskaran Unnikrishnan, Ramesh Holla, Vaman Kulkarni, B. B. Darshan, Avinash Kumar

“…Background. HIV/AIDS has a greater impact on children. Besides being orphaned by the untimely demise of one or both parents due to the disease, these children are more prone for discrimination by the society. …”
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Emergency response in overturned pig transport vehicles: Description and discussion of Danish cases from a One Welfare perspective by Cecilie Kobek-Kjeldager, Kirstin Dahl-Pedersen, Mette S Herskin

“…The description is followed by a discussion of six identified themes related to animal welfare and One Welfare in such situations: (1) Standard operating procedures; (2) Balancing animal welfare and work safety; (3) Roles, education and experience; (4) Communication, time and access to animals; (5) Debriefing; and (6) Killing of animals. …”
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Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decorticati... by Liz Darlison, John Edwards, Apostolos Nakas, Nick A Maskell, Wendy Underwood, Chris Rogers, Matthew Callister, David Waller, Richard Milton, Victoria Ashford-Turner, Paul Taylor, Claire Matthews, Victoria Hughes, Kelvin Lau, Alan Kirk, Robert C Rintoul, Elizabeth A Stokes, Kate Ashton, Daisy Elliott, Rosie Harris, Marie Kirwan, Juliette Novasio, Sara Waplington, Eric Lim, Holly Mckeon, Charlotte Jacobs, Laura White, Mary O’Brien, Judith Moore, Louise Li, Nicola Mills, Sanjay Popat, Suzanne Miller, Nadia Yousaf, D A Fennell, Clinton Ali, Andrea Bille, Liz Fuller, Andreea Ionescu, Manjusha Keni, Pek Koh, Talal Mansy, Dakshinamoorthy Muthukumar, Tony Pope, Amy Roy, Riyaz Shah, Jonathan Shamash, Zacharias Tasigiannopoulos, Sarah Treece, Katherine Joyce, Barbara Warnes, Athanasia Gravani, Rachel Brophy, Nicola Farrar, Jane Elliott, Philip Noyes, Louise Nelson, Sara Tenconi, Laura Socci, Hilary Wood, Helena Hanratty, Helena Stanley, Robert Rintoul, Amy Gladwell, Jenny Castedo, Amanda Stone, Charlotte Ingle, Hayley Hewer, Eleanor Aynsley, Andrea Watson, Alison Hassall, Masuma Begum, Christopher Worth, Ellie Piggott, Elizabeth Nadin, Yvonne Summers, Raffaele Califano, Laura Cove-Smith, Matt Evison, Maria Blinston, Amal Ismail, Rachel Chant, Asmita Desai, Ian Morgan, Victoria Lake, Nichola Harris, Simon Hodge, Nadza Tokaca, Adam Januszewski, Avani Athauda, Anisha Ramessur, Emily Grist, Niamh Colman, Michael Flynn, Joan Joyce, Sarah Vaughan, Maria Piga, Derya Sahin, Agnieszka Yongue, Emma Turay, Jaishree Bhosle, Rajiv Kumar, Charlotte Milner-Watts, Jessica Brown, David Walder, Alexandros Georgiou, Xiaorong Wu, Naila Kaudeer, Kroopa Joshi, Michael Davidson, Shelize Khakoo, Bee Ayite, Kathryn Priest, James Dobbyn, Vasanthi Prathapan, Deborah McCrimmon, Natalie Ash, Alison Norton, Bianca Peet, Libby Hennessy, Rosemary Johnson

“…Introduction Mesothelioma remains a lethal cancer. To date, systemic therapy with pemetrexed and a platinum drug remains the only licensed standard of care. …”
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Investigating a caregiver-assisted social skills group programme for primary and early high school-aged children with acquired brain injury or cerebral palsy: protocol for a pilot... by Koa Whittingham, Roslyn N Boyd, Rose Gilmore, Leanne Sakzewski, Nicola Hilton, Afroz Keramat, Bianca Thompson, Jacqui Barfoot, Christine T Moody

“…Analyses will follow standard principles for randomised controlled trials using two-group comparisons on all participants on an intention-to-treat basis. …”
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Effects of Cognitive Behavior Therapy on Heart Rate Variability among Medical Students at a Teaching Institution in Jaipur, India by Neha Saboo, Sudhanshu Kacker, Jitender Sorout

“…Results: Findings show that there was a significant decrease in linear components, i.e., time domain and frequency domain parameters (P < 0.001) and nonlinear components Poincare plot standard deviation (SD) 1/SD2 (P < .0.001) after 3 months of CBT. …”
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The current status of the use of genetic modification and editing to improve biodiversity and ecological sustainability by Gideon Sadikiel Mmbando, Kelvin Ngongolo

“…We found that the slow use of GME technologies was due to the public's varied ethical perspectives, which are influenced by cultural, religious, and ethical consumerism factors. …”
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