Concurrent Extraction and Analysis of Atmospheric Particulate Matter-bound PBDEs, PAHs, Nitrated PAHs, and OPEs by Hsin-Chieh Kung, Bo-Wun Huang, Chien-Er Huang, Nicholas Kiprotich Cheruiyot, Guo-Ping Chang-Chien

“…The detected values of the SRM samples (n = 4) were all within 30%, except for 3 N-PAH congeners. The recovery rates for the spiked concentrations (n = 5) were 82.2% ± 8.7%–122% ± 4.4% for PBDEs, 84.2% ± 9.9%–115% ± 17.4% for PAHs, 83.2% ± 2.2%–111% ± 2.5% for N-PAHs, and 93.9% ± 5.3%–111% ± 10.7% for OPEs. …”
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The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. by Alexander M Cole, Dorothy L Patton, Lisa C Rohan, Amy L Cole, Yvonne Cosgrove-Sweeney, Nicole A Rogers, Deena Ratner, Alexandra B Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I Lehrer, Alan J Waring, Phalguni Gupta

“…<h4>Background</h4>RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major clades, does not hemagglutinate, and is non-toxic and non-inflammatory in cervicovaginal cell culture. …”
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Honoring the Afro-Colombian musical culture with the naming of Epipedobates currulao sp. nov. (Anura, Dendrobatidae), a frog from the Pacific rainforests by Mileidy Betancourth-Cundar, Juan Camilo Ríos-Orjuela, Andrew J. Crawford, David C. Cannatella, Rebecca D. Tarvin

“…This taxon differs from congeners by having a combination of bright yellow blotches in the dorsal anterior region of the thigh and upper arm, homogenous dark-brown dorsal coloration, and advertisement calls of long duration and many pulses. …”
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The relationship between the genetic status of the Vrn-1 locus and the size of the root system in bread wheat (Triticum aestivum L.) by O. G. Smirnova, T. A. Pshenichnikova

“…A significant increase in the root size of line 821 with introgressions into chromosomes 2A, 2B, and 5A from T. timopheevii indicates the possibility of using congeners as a source of increasing the trait in wheat.…”
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Association between gut microbiota and short-chain fatty acids in children with obesity by Shihan Li, Xinyu Ma, Hong Mei, Xuening Chang, Peiling He, Lingli Sun, Han Xiao, Shiqiong Wang, Ruizhen Li

“…This case–control study recruited children aged 7‒14 years and divided them into a normal group (NG) and an obese group (OG) based on their body mass index. Whole-genome shotgun metagenomic analysis was performed on fecal samples from the OG and NG groups to characterize the signatures and functional potential of the gut microbiota. …”
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Functional constipation by Yu. O. Shulpekova, A. A. Kurbatova, A. V. Sedova

“…Promising results are received at administration of specific strains of bifidobacteria and lactobacilli, in particular the combined probiotic «Florasan D» that includes Bifidobacterium bifidum, B.longum, B. infantis, Lactobacillus rhamnosus. Largescale studies proving efficacy of B. lactis DN-173 010 strain (the commercial name «ActiRegularis») at constipation and functional flatulence are received, the drug is included to the spectrum of functional nutritional products for daily intake.…”
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Longitudinal monitoring of sewershed resistomes in socioeconomically diverse urban neighborhoods by Jangwoo Lee, Kevin Xiang, Emily Au, Shahrzad Sarabi, Nicole Acosta, Srijak Bhatnagar, Jennifer Van Doorn, Stefania Bertazzon, John M. Conly, Elissa Rennert-May, Johann D. D. Pitout, Bonita E. Lee, Xiaoli Pang, Christine O’Grady, Kevin Frankowski, Casey R. J. Hubert, Michael D. Parkins

“…Resistomes were established by shotgun-sequencing of wastewater pellets, and qPCR of targeted-AMR genes. …”
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Alpha synuclein overexpression can drive microbiome dysbiosis in mice by Timothy R. Sampson, Zachary D Wallen, Woong-Jai Won, David G. Standaert, Haydeh Payami, Ashley S. Harms

“…Here, we used a transgenic mouse strain, which overexpress wild-type human α-syn to test how the gut microbiome composition responds in this model of PD pathology during aging. Using shotgun metagenomics, we find significant, age and genotype-dependent bacterial taxa whose abundance becomes altered with age. …”
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Comparing subsampling strategies for metagenomic analysis in microbial studies using amplicon sequence variants versus operational taxonomic units. by Daniel Segura, Divya Sharma, Osvaldo Espin-Garcia

“…Due to the high cost of shotgun metagenomic sequencing (SM-seq), microbiome analyses can be done cost-effectively in two phases: Phase 1-sequencing of 16S ribosomal RNA, and Phase 2-SM-seq of an informative subsample. …”
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Genomic insights into multidrug-resistant Acinetobacter baumannii strains isolated from Dhaka, Bangladesh by Sadia Ferdous, K M Shayerul Abedin Shayer, Afia Anjum, Sabbir R. Shuvo, Ishrat Jabeen, Kristi Paul Hridi, A.K.M. Imrul Hassan, Md Imran Khan, Mohammad Fazle Alam Rabbi, Mahmud Hossain, Kazi Nadim Hasan, Sohidul Islam

“…Five MDR, biofilm-forming A. baumannii strains isolated from clinical samples in Dhaka, Bangladesh, underwent a comprehensive whole-genome shotgun sequencing. In silico analyses determined strain types, antibiotic resistance, and virulence genes. …”
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Cytotoxic mechanisms of pemetrexed and HDAC inhibition in non-small cell lung cancer cells involving ribonucleotides in DNA by Tobias Solli Iveland, Lars Hagen, Mirta Mittelstedt Leal de Sousa, Nina Beate Liabakk, Per Arne Aas, Animesh Sharma, Bodil Kavli, Geir Slupphaug

“…Proteomic alterations were analyzed using label-free shotgun and targeted LC–MS/MS. MS275 enhanced the sensitivity of A549 cells to pemetrexed, but only when administered following prior treatment with pemetrexed. …”
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Survey of the Applications of NGS to Whole-Genome Sequencing and Expression Profiling by Jong-Sung Lim, Beom-Soon Choi, Jeong-Soo Lee, Chanseok Shin, Tae-Jin Yang, Jae-Sung Rhee, Jae-Seong Lee, Ik-Young Choi

“…Both massive whole-genome shotgun paired-end sequencing and mate paired-end sequencing data are important steps for constructing de novo assembly of novel genome sequencing data. …”
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High-throughput sequence-based microsatellite genotyping for the non-model Neotropical tree species Anadenanthera colubrina (Leguminosae) by Alejandra Lorena Goncalves, María Victoria García, Emilie Chancerel, Olivier Lepais, Myriam Heuertz

“…Next-generation sequencing (NGS) strategies allow simple and cost-effective development of new SSR loci from low-coverage whole genome shotgun sequencing. The main aim was to develop microsatellite markers for sequence-based high-throughput genotyping (SSRseq) in the species and to characterize their information content against traditional capillary electrophoresis-based microsatellite data by estimating the amount of molecularly accessible size homoplasy of each locus. …”
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Medidas para la protección del medio marino en la región del Gran Caribe por daños ocasionados por la industria mar adentro by María Carolina Romero Lares

“…En la actualidad no existe ningún convenio internacional que aborde el tema, y la comunidad internacional se ha inclinado a favor del desarrollo de instrumentos regionales o bilaterales. …”
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La formación del profesorado: un compromiso entre visiones inconciliables de la coherencia by Philippe Perrenoud

“…A pesar de ello se propone en este artículo un análisis de la coherencia de la formación docente centrado en torno a catorce dimensiones clave. En ningún caso se pretende que esta lista de dimensiones sea definitiva sino que se anima a los lectores a que la modifiquen, completen y reelaboren. …”
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Effects of dietary olive oil, camellia seed oil and soybean oil on serum lipid composition in women with a high risk of cardiovascular disease: a lipidomic analysis by Minyu Wu, Changfeng Hu, Lirong Shen

“…In this study, multidimensional mass spectrometry-based shotgun lipidomics was used to examine the serum lipidomics of participants in a clinical randomized controlled feeding trial undergoing olive oil (OO), camellia seed oil (CSO), and soybean oil (SO) dietary interventions. 189 lipid molecules are identified, including 14 species of phosphatidylinositol, 45 species of ethanolamine glycerols (PE), 47 species of choline glycerophospholipids (PC), 39 species of triacylglycerols (TAG), 18 species of lysophosphatidylcholine, and 26 species of sphingomyelin. …”
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Frecuencia de grupos sanguíneos ABO y Factor Rh en estudiantes ingresantes a la Universidad Nacional Jorge Basadre Grohmann by Anthony Brayan Rivera-Prado, Kelly Geraldine Yparraguirre-Salcedo, Magyori Araceli Velásquez-Pari, Vicente Freddy Chambilla-Quispe

“…Respecto a las frecuencias de acuerdo a la facultad, todas presentan como grupo mayoritario al grupo O positivo: FAIN (19,42 %), FCAG (20,21 %), FECH (18,94 %), FIAG (10,34 %), FCJE (8,29 %), FACS (16,65 %) y FACI (6,15 %). No se reportó ningún caso de grupo sanguíneo B Rh negativo y AB Rh positivo. …”
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Discovery of 15-deoxynaphthomycins activating the antioxidant NRF2-ARE pathway from Streptomyces sp. N50 via genome mining, global regulator introduction, and molecular networking by Min-Seon Kim, Baskar Selvaraj, Hee-Tae Yeo, Jun-Su Park, Jae Wook Lee, Jin-Soo Park

“…Furthermore, molecular network analysis via MS/MS selectively confirmed the presence of additional sulfur-containing 15-deoxynaphthomycin congeners. Eventually, six new 15-deoxynaphthomycins were isolated and elucidated from the engineered strain N50. …”
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Observational study protocol: the faecal microbiome in the acute stage of new-onset paediatric type 1 diabetes in an Irish cohort by Eugene Dempsey, Catherine Stanton, Paul Ross, Colin Patrick Hawkes, Aonghus Lavelle, Carol-Anne O’Shea, Elaine Catherine Kennedy, Fiona Catherine Ross

“…The study will also explore possible associations between the microbiome, metabolome, glycaemic control and beta cell reserve.Methods and analysis This prospective cohort study will include children with newly diagnosed T1D and sibling controls (n=100, males and females) and their faecal microbiome will be characterised using shotgun metagenomic sequencing at multiple time points during the first year of diagnosis. …”
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Licencias Comerciales para el Desarrollo Rural con Enfoque Ecoturístico del Estado de Guerrero México by Noemí Ascencio López, Frida Carpio Clemente, Georgina De León Vargas

“…Como principales resultados Es necesario que las autoridades de los diferentes niveles de gobierno pongan especial énfasis en la planificación y debido desarrollo comercial de las zonas rurales, esto para prevenir riesgos y ofrecer a los visitantes una experiencia segura y ordenada; además, se deben diseñar políticas públicas que permitan realizar lo anterior, así como facilitar a los habitantes de estas zonas los elementos necesarios para ofrecer productos y servicios de calidad. …”
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