Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors by Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio, Julien Taieb, David Tougeron, Margherita Ambrosini, Michael J Overman, Alice Boilève, Lisa Salvatore, Rosine Guimbaud, Priya Jayachandran, Frank A Sinicrope, Thibault Mazard, Javier Ros, Vincenzo Nasca, Simon Pernot, Emily Alouani, Marie Decraecker, Emilie Hafliger, Pauline Parent

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Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39 by Zhongxiao Fu, Mallikarjunarao Ganesana, Philip Hwang, Xiao Tan, Melissa Marie Kinkaid, Yu-Yo Sun, Emily Bian, Aden Weybright, Hong-Ru Chen, Katia Sol-Church, Ukpong B. Eyo, Clare Pridans, Francisco J. Quintana, Simon C. Robson, Pankaj Kumar, B. Jill Venton, Anne Schaefer, Chia-Yi Kuan

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Sex Disparities of Health-related Quality of Life in Moderate to Severe Psoriasis: A Real-world Analysis from the Swiss Psoriasis Registry (SDNTT) by Ramtin Lichtenberger, Lara Valeska Maul, Ion Birkenmaier, Iker Oyanguren, Melike Ak, Kristine Heidemeyer, Christoph Schlapbach, Nikhil Yawalkar, Alexander Egeberg, Simon Francis Thomsen, Jacob P. Thyssen, Christina Sorbe, Wolf-Henning Boehncke, Curdin Conrad, Antonio Cozzio, Georgios Kokolakis, Raphael Micheroli, Jashin J. Wu, Thomas Kündig, Alexander Navarini, Julia-Tatjana Maul

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Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production by Heather J Bax, Jitesh Chauhan, Alexandra J McCraw, Melanie Grandits, Chara Stavraka, Heike Lentfer, Tim Hillyer, Simon Carroll, Kim Vigor, Chris Selkirk, Mariangela Figini, Jack Cheeseman, Paulina A Urbanowicz, Richard A Gardner, Daniel I R Spencer, Nigel Westwood, Sarah Mellor, James Spicer, Debra H Josephs, Sophia N Karagiannis

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Recruitment, follow-up and survival in an 11-country cohort study of patients at the end of life and their relatives. by Maria E C Schelin, Christel Hedman, Pilar Barnestein-Fonseca, Martina Egloff, John Ellershaw, Dagny Faksvåg Haugen, Claudia Fischer, Melanie Joshi, Ida J Korfage, Urška Lunder, Stephen Mason, Judit Simon, Vilma A Tripodoro, Berivan Yildiz, Sofia C Zambrano, Steffen Eychmueller, Lia van Zuylen, Agnes van der Heide, Carl Johan Fürst, iLIVE Consortium

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A morphometric signature to identify ductal carcinoma in situ with a low risk of progression by Marcelo Sobral-Leite, Simon P. Castillo, Shiva Vonk, Hendrik A. Messal, Xenia Melillo, Noomie Lam, Brandi de Bruijn, Yeman B. Hagos, Myrna van den Bos, Joyce Sanders, Mathilde Almekinders, Lindy L. Visser, Emma J. Groen, Petra Kristel, Caner Ercan, Leyla Azarang, Jacco van Rheenen, E. Shelley Hwang, Yinyin Yuan, Grand Challenge PRECISION Consortium, Renee Menezes, Esther H. Lips, Jelle Wesseling

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Cluster randomised controlled trial of screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the pilot study for the SAFER trial by Martin R Cowie, Stephen Morris, Gregory Lip, Richard J McManus, Stephen Sutton, Jonathan Mant, Simon J Griffin, Sarah Hoare, Jenni Burt, Rachel Johnson, Mark Lown, Alison Powell, Natalie Armstrong, FD Richard Hobbs, Trudie Lobban, Rakesh Narendra Modi, Ben Freedman, David A Fitzmaurice, Stephen Kaptoge, Jenny Lund, Duncan Edwards, Kate Williams, H Thom, Francesco Fusco, Michael J Sweeting, Andrew Dymond, The SAFER Authorship Group

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Individual participant data meta-analysis of trials comparing frozen versus fresh embryo transfer strategy (INFORM): a protocol by Lan N Vuong, Rui Wang, Ben W Mol, Rong Li, Karin Hammarberg, Kate Brian, Yun Sun, Pollyanna Hardy, Anja Pinborg, Siladitya Bhattacharya, Sacha Stormlund, David J McLernon, Zi-Jiang Chen, Richard S Legro, Carlos Simon, Shimona Lai, Marian G Showell, Daimin Wei, Ze Wang, Keliang Wu, Xavier Santamaría, Christophe Blockeel, Femke Mol, Anna P Ferraretti, Bruce S Shapiro, Forest C Garner, Christos A Venetis, Abha Maheshwari, Gwenda Burns

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The efficacy of conservative management of micro-traumatic posterior shoulder instability by Lyn Watson, Prof DocBAppSci(Physio) GradDip, Simon Balster, BPhty(Hon), BSc (Hon), Sarah Warby, PhDB Physio (Hon), Ross Lenssen, BHSc(Physiotherapy), Gregory Hoy, MBBS, FRACS, FAOrthA, FACSP, Shane Barwood, MBBS, FRACS, Jacqui French, BPhysio, Bonnie Kerr, BHth ScMSports Physio, Sam Lawrence, DPT, BAppSc, PGCert, Charlotte Ganderton, PhDB Physio (Hon), Katherine Davis, BHuman Movt (ExSci), MPhysio, Tania Pizzari, PhDB Physio (Hon)

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Circulating Stress Hormones, Brain Health, and Cognition in Healthy Older Adults: Cross-Sectional Findings and Sex Differences in Age-Well by Maxie Liebscher, Silke White, Simon Hass, Anne Chocat, Florence Mezenge, Brigitte Landeau, Marion Delarue, Oriane Hébert, Anne-Laure Turpin, Natalie L. Marchant, Gaël Chételat, Olga Klimecki, Géraldine Poisnel, Miranka Wirth, Claire André, Pierre Champetier, Léa Chauveau, Fabienne Collette, Sophie Dautricourt, Robin de Flores, Vincent De La Sayette, Harriet Demnitz-King, Séverine Fauvel, Francesca Felisatti, Victor Ferment, Eglantine Ferrand-Devouge, Julie Gonneaud, Antoine Garnier-Crussard, Anaïs Hamel, Sacha Haudry, Pierre Krolak-Salmon, Elizabeth Kuhn, Valérie Lefranc, Antoine Lutz, Valentin Ourry, Cassandre Palix, Anne Quillard, Géraldine Rauchs, Eric Salmon, Edelweiss Touron, Patrik Vuilleumier, Tim Whitfield

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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context by Podjanee Jittamala, Simon Boyd, William H.K. Schilling, James A. Watson, Thundon Ngamprasertchai, Tanaya Siripoon, Viravarn Luvira, Elizabeth M. Batty, Phrutsamon Wongnak, Lisia M. Esper, Pedro J. Almeida, Cintia Cruz, Fernando R. Ascencao, Renato S. Aguiar, Najia K. Ghanchi, James J. Callery, Shivani Singh, Varaporn Kruabkontho, Thatsanun Ngernseng, Jaruwan Tubprasert, Wanassanan Madmanee, Kanokon Suwannasin, Amornrat Promsongsil, Borimas Hanboonkunupakarn, Kittiyod Poovorawan, Manus Potaporn, Attasit Srisubat, Bootsakorn Loharjun, Walter R.J. Taylor, Farah Qamar, Abdul Momin Kazi, M. Asim Beg, Danoy Chommanam, Sisouphanh Vidhamaly, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Arjen M. Dondorp, Nicholas P.J. Day, Mauro M. Teixeira, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Nicholas J. White

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Disparities in dolutegravir utilisation in children, adolescents and young adults (0–24 years) living with HIV. An analysis of the IeDEA Pediatric West African cohort by Valériane Leroy, Anandi Sheth, Julie Jesson, Jean Jacques Koffi, Antoine Jaquet, François Dabis, Didier Koumavi Ekouevi, Karen Malateste, Olivia Keiser, Lehila Bagnan, Simon Boni, Madeleine Amorissani Folquet, Mariam Sylla, Olivier Marcy, Raoul Moh, Gildas Boris Hedible, Sophie Desmonde, Joycelyn Dame, Agatha David, Madeleine Amorissani-Folquet, Sylvie N'Gbeche, Elom Takassi, François Tanoh Eboua, Kouadio Kouakou, Lehila Bagnan Tossa, Caroline Yonaba, Jocelyn Dame, Sylvie Marie N’Gbeche, Fatoumata Dicko Traore, Oliver Ezchechi, Rosemary Audu, Charlotte Bernard, Caroline Couturier, Marie Kerbie Plaisy, Elodie Rabourdin, Thierry Tiendrebeogo, Désiré Dahourou, Emile Sodinyessi, Jean-Claude Azani, Kadidja Diarra, Maika Bengali, Abdoulaye Cissé, Guy Gnepa, Eric Komena, Séverin Lenaud, Eulalie Kangah, Igho Ofotokun, Cecile Delille Lahiri, Noëlle Benzekri, Geoffrey Gottlieb

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Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective coho... by Stefanie Aeschbacher, David Conen, Diederick E Grobbee, Raphael Twerenbold, Thomas Lung, Theo Rispens, Jakob Kjellberg, Lorenz Risch, Martin Risch, Marianna Mitratza, Harald Renz, Spiros Denaxas, Billy Franks, Diederick Grobbee, Martina Rothenbühler, Janneke Wijgert, Santiago Montes, Richard Dobson, Hans Reitsma, Christian Simon, Titia Leurink, Charisma Hehakaya, Patricia Bruijning, Kirsten Grossmann, Ornella C Weideli, Marc Kovac, Fiona Pereira, Nadia Wohlwend, Corina Risch, Dorothea Hillmann, Daniel Leibovitz, Vladimir Kovacevic, Andjela Markovic, Paul Klaver, Timo B Brakenhoff, George S Downward, Ariel Dowling, Maureen Cronin, Brianna M Goodale, Brianna Goodale, Ornella Weideli, Regien Stokman, Hans Van Dijk, Eric Houtman, Jon Bouwman, Kay Hage, Lotte Smets, Marcel van Willigen, Maui Chodura, Niki de Vink, Tessa Heikamp, Timo Brakenhoff, Wendy van Scherpenzeel, Wout Aarts, Alison Kuchta, Antonella Chiucchiuini, Steve Emby, Annemarijn Douwes, George Downward, Nathalie Vigot, Pieter Stolk, Duco Veen, Daniel Oberski, Amos Folarin, Pablo Fernandez Medina, Eskild Fredslund

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Understanding the experiences of young, urban, Indigenous mothers-to-be in British Columbia, Canada by Nicole L. A. Catherine, Jennifer Leason, Namaste Marsden, Brittany Barker, Ange Cullen, Ashley Simpson, Brandi Anne Berry, Erik Mohns, Donna Yung, Yufei Zheng, Harriet MacMillan, Charlotte Waddell

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A Computational Turn in Policy Process Studies: Coevolving Network Dynamics of Policy Change by Maxime Stauffer, Isaak Mengesha, Konrad Seifert, Igor Krawczuk, Jens Fischer, Giovanna Di Marzo Serugendo

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Effects of nurse-home visiting on intimate partner violence and maternal income, mental health and self-efficacy by 24 months postpartum: a randomised controlled trial (British Col... by Susan Jack, Charlotte Waddell, Michael Boyle, Harriet MacMillan, Yufei Zheng, Hui Xie, Colleen Varcoe, Amiram Gafni, Andrea Gonzalez, Debbie Sheehan, Lil Tonmyr, Ronald Barr, Lenora Marcellus, Nicole L A Catherine

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Investigating the Quality of DermaMNIST and Fitzpatrick17k Dermatological Image Datasets by Kumar Abhishek, Aditi Jain, Ghassan Hamarneh

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Cohort profile: the BangladEsh Longitudinal Investigation of Emerging Vascular and nonvascular Events (BELIEVE) cohort study by Anisur Rahman, Stephen Sutton, Mahbubur Rahman, Jason Crawte, Tahmeed Ahmed, Md Saimul Islam, Aliya Naheed, Adam S Butterworth, Emanuele Di Angelantonio, Matthew Walker, John Danesh, Angela Wood, Sarah Hawkes, Sadika Akhter, Catherine Perry, Aytalina Azarova, Ruchira T Naved, Meerjady Sabrina Flora, Nusrat Khan, Rajiv Chowdhury, Sohel Reza Choudhury, Nusrat Jahan, Stephen Kaptoge, Md Zahidul Islam, Kaniz Fatema, Kim Robin van Daalen, Shammi Luhar, Roderic L Jones, Abbas Bhuiya, Md Khalequzzaman, Syed Shariful Islam, Henry Taylor, Shamima Akter, Simon Griffin, Khairul Islam, Salma Akter, Ruchira Tabassum Naved, Abdul Malik, Rubhana Raqib, Animesh Talukder, Richard Houghton, Tahmina Shirin, Lawrence King, Kamrun Nahar, Samantha Farrow, Giulia Loffreda, Samsad Rabbani Khan, Valerie Rhenius, Nahida Akter, Md Mostafa Monower, Sabina Akter, Mantaka Rahman, Lisa Pennells, Maria L C Iurilli, Md Taslim Uddin Miah, Khan Mohammad Thouhidur Rahman, Sharraf Samin, Kazi Nazmus Saqeeb, Ishrat Tasmin, Eleanor Farrow, Ank Michielsen, Sarah Spackman, Charlotte van Coeverden, James Ajioka, Khondker Abdul Abdul Awal, Evangelia Chatzidiakou, Jörg Feldmann, Richard Fenner, Tuhin Haque, Sirajul Islam, Kamrul Hasan Khan, Fazila-Tun-Nesa Malik, Olalekan Popoola, Nicholas Mascie Taylor, Md Alfazal Khan, Israt Akter, Laboni Akter, Shoriful Islam, Mohammad Kamruzzaman, Monalisa Moni, A H M Rezwan, K M Thouhidur Rahman, Monjeline Sultana, Jesmin Akhter, Ayasha Akter, Bakul Akter, Jharna Akter, Jesmin Akter, Juba Akter, Khadiza Akter, Khadija Akter, Lipi Akter, Maksuda Akter, Mousumi Akter, Mst Lovely Akter, Nasima Akter, Samima Akter, Sema Akter, Shahida Akter, Shahnaj Akter, Taslima Akter, A T M Zorjis Alam, Mahmuda Atique, Lutfa Begum, Mst Nazma Begum, Farjana Choudhury, Mitali Paul Chowdhury, Robin Reza Chowdhury, Mukul Rani Debnath, Nahid Ferdash, Naima Ferdous, Md Rakib Al Hasan, Khandaker Hashanuzzaman, Shamima Haq, Md Riazul Haque, Alamgir Hossain, Md Ibrahim, Shahi Israt Jahan, Israt Jahan Jarin, Zohora Pradhan Jonaki, Asik Kabir, Tonema Kader, Md Mostafa Kamal, Sayed Kamruzzaman, Sadik Fatima Kanon, Nazmul Karim, Shamsul Karim, Tanuja Khanom, Shamim Ara Khatun, Badrun Nahar Lorin, Mst Sirajum Manira, Farhana Jahan Mary, Kazi Dilruba Mita, Lipi Mitra, Basudeb Mollik, Sudipta Nargis, Nusrat Alam Nawmee, Esrat Zahan Nesa, Mahmuda Akter Nipa, Mehenaz Parvin, Sanjida Parvin, Shahnaj Parvin, Suraiya Parvin, Nayan Rabidash, Rulia Rahman, Madhabi Rani, Shahjalal Sarker, Smriti Sarker, Razia Sultana Shathi, Fatema Shelly, Ireen Sultana, Rovaiya Sultana, Israt Jahan Sumi, Sharmin Tamanna, Khadija Akter Topy, Umme Habiba Urmee, Suraya Yesmin, Julianne Halley, Charlotte van Coeverden, Mahmuda Akther Akhi, Asia Akter, Labony Akter, Ms Mili Akter, Mst Shamima Akter, Setu Akter, Tahmina Akter, Md Sabdar Ali, Mst Jesmin Ara, Edyta Bujnik, Apu Chandra Das, Many Das, Nurjahan Fatema, Md Riyad Hasan, Soniya Jannat, Mst Amena Khatun, Most Nurnahar Khatun, William Mossman, Robyn Murdoch, Zannaton Naeem, Evrikleia Ntasi, Silvia Alonso Rodriguez, Tripty Roy, Most Abida Sultana, Laryssa Amado, Tanya Braune, Eilidh Cowan, Steve Ellis, Ellie Farrow, Hannah Lombardi, Niko Ovenden, Tamara Sabri, Md Khalid Sultan, Jim Ajioka, Khondker Abdul Awal, Arul Baradi, Emanuele Di Angelantonio, Camilla Faidutti, Joerg Feldmann, Louise Hair, Sharifuddin Hasnat, Shahid Akhter Hossain, Md Mominul Islam, Shafiul Islam, Joe Lavallée, Fazila Tun-Nesa Malik, Nick Mascie-Taylor, Md Sirajul Islam, Laurie Savage, Sara Shazad, Lalitha Sundaram, Aloka Tulukdar, Kim Van Daalen, Tanvir Chowdhury, Nurul Huda, Samia Naz Isha, Riaz Hossain Khan, Aliva Salmeen, Zeeba Zahra Sultana

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A New (Related-Key) Neural Distinguisher Using Two Differences for Differential Cryptanalysis by Gao Wang, Gaoli Wang, Siwei Sun

“…In addition, we give a framework to automatically train our (related-key) differential neural distinguisher with four steps: difference selection, sample generation, training pipeline, and evaluation scheme. To demonstrate the effectiveness of our approach, we apply it to the block ciphers: Simon, Speck, Simeck, and Hight. …”
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Enhancing Enzyme-Mediated Cellulose Hydrolysis by Incorporating Acid Groups Onto the Lignin During Biomass Pretreatment by Jie Wu, Richard P. Chandra, Masatsugu Takada, Masatsugu Takada, Li-Yang Liu, Scott Renneckar, Kwang Ho Kim, Chang Soo Kim, Jack N. Saddler

“…When Simon’s stain was used to assess potential enzyme accessibility to the cellulose, it was apparent that both post-treatments enhanced accessibility and cellulose hydrolysis. …”
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