Response mechanism of ethanol-tolerant Saccharomyces cerevisiae strain ES-42 to increased ethanol during continuous ethanol fermentation by Xue-Xue Ji, Quan Zhang, Bai-Xue Yang, Qing-Ran Song, Zhao-Yong Sun, Cai-Yun Xie, Yue-Qin Tang

“…Results During continuous fermentation, as ethanol concentration increased, the expression of genes associated with cytoplasmic ribosomes, translation, and fatty acid biosynthesis progressively declined, while the expression of genes related to heat shock proteins (HSPs) and ubiquitin-mediated protein degradation gradually increased. …”
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Human inborn errors of immunity underlying Talaromyces marneffei infections: a multicenter, retrospective cohort study by Huifeng Fan, Zhiyong Yang, Yuhui Wu, Xiulan Lu, Tian Li, Xuyang Lu, Gen Lu, Liming He, Guoping Lu, Li Huang

“…The most common severe complications included septic shock, hemophagocytic lymphohistiocytosis (HLH), and acute respiratory distress syndrome (ARDS). …”
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Decreased Spp1 Expression in Acute Myocardial Infarction after Ischemia and Reperfusion Injury by Ling Li, Jungang Huang, Zongkai Zhao, Zhuzhi Wen, Kang Li, Tianjiao Ma, Lisui Zhang, Junmeng Zheng, Shi Liang

“…Background. With the progress of shock therapy and the establishment and promotion of methods such as thrombolytic therapy and percutaneous coronary intervention (PCI), many tissues and organs have been reperfused after ischemia which may cause even worse disorder called ischemia-reperfusion injury (IRI). mRNAs have been found to have significant impacts on ischemia-reperfusion through various mechanisms. …”
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Which combination of medical expulsive therapy is more effective for treatment of distal ureteral stone in adults? A systematic review and network meta-analysis by Maryam Taheri, Nasrin Borumandnia, Hamidreza Abdi, Amir H Kashi, Setareh Nourani, Sogand Sheikholeslami, Yasamin Maleki Gilvaei, Pardis Ziaeefar, Abbas Basiri

“…We excluded articles that looked at MET for upper ureteral stone passage or after shock wave lithotripsy (SWL). NMA was performed to compare the effect of combination MET on stone expulsion rate (SER), stone expulsion time (SET), and need for analgesia. …”
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Effect of Prolonged-Release Pirfenidone on Renal Function in Septic Acute Kidney Injury Patients: A Double-Blind Placebo-Controlled Clinical Trial by Jonathan S. Chávez-Iñiguez, Jorge L. Poo, Miguel Ibarra-Estrada, Leonel García-Benavides, Guillermo Navarro-Blackaller, Cynthia Cervantes-Sánchez, Eduardo Nungaray-Pacheco, Ramón Medina-González, Juan Armendariz-Borunda, Guillermo García-García

“…The main site of infection was the lung (39.8%), septic shock was present in 39.1% of the cases, and the mean SOFA score was 8.8 points. 28 patients received PFD 1,200 mg, 30 patients received PFD 600 mg, and 30 patients received placebo. …”
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Case report: Accidental aconitine poisoning caused by the inappropriate use of a type of Chinese patent medicine by Ruikai Shang, Ruikai Shang, Hongyu Liu, Qiaoxin Tian, Qiaoxin Tian, Yuru Liu, Xiangdong Jian, Xiangdong Jian, Qilu Li

“…However, improper use and overdose can easily cause acute poisoning, leading to malignant arrhythmias, cardiogenic shock, and even death.MethodsThis study retrospectively analyzed the clinical data of eight patients who were treated in our hospital from June 2023 to February 2024 after taking compound schizonepeta fumigation lotion by mistake.Case presentationWe report 8 cases of patients who took compound schizonepeta fumigation lotion by mistake. …”
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Yoruba Epistemology, Art, Language and the Universe of Meanings: A Meta-Analysis by Michael O. Afolayan

“…It got me thinking. It is a needed shock therapy, an organic rendition of an intellectual exposition of the Yoruba art. …”
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Prognostic value of HSP27 in 28-day mortality in septic ICU patients: a retrospective cohort study by Lihua Yao, Lihua Yao, Zaiwei Fan, Fangyi Yao, Xiaozhong Wang

“…BackgroundThis study aimed to investigate the association between serum heat shock protein 27 (HSP27) levels and 28-day mortality in patients with sepsis.MethodsThis retrospective study analyzed the clinical data of 76 septic patients admitted to the intensive care unit (ICU). …”
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The effect of educational programs on parents’ knowledge, behavior, and practices regarding aluminum phosphide poisoning and its first-aid measures by Mabrouka Attia Ali Nada, Ahmed Kamal Eldin Elsayed Elfeky, Hamida Ahmed Mustafa Darweesh, Farida Khalil Ibrahim Mohamed, Loujain Saud Sharif, Faten Shawky Kandil, Fatma Ahmed Elsobky, Samah Abdallah Mohamed Amer

“…Clinical findings included vomiting (76.6%), dyspnea (77.5%), and cardiogenic shock (84.8%). ECG abnormalities were found in 82.7% of patients, and metabolic acidosis was present in 82.3% of patients. …”
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Factores asociados a la mortalidad de pacientes geriátricos graves ingresados en cuidados intensivos by Wilfredo Hernández Pedroso, Ricardo González Mesana, Aliusha Rittoles Navarro, Rafael Venegas Rodríguez, Raúl Santana Sánchez, Daily Chacón Montano

“…La causa directa de muerte más frecuente fue el shock séptico y la causa básica, la enfermedad ateroesclerótica. …”
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Clinical and microbiological characteristics and prognosis of invasive infection caused by Klebsiella pneumoniae in the community by Hongkui Sun, Hanlin Zhang, Wenqing Lai, Li Lei, Jianwei Li, Miaolian Chen, Haijun Li, Zhanyuan Zhao

“…Multivariate logistic regression analysis identified high viscosity type (OR:2.26, p = 0.031) and shock (OR:3.42, p = 0.001) as significant risk factors for invasive infection. …”
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Genetic diversity of VIR Raphanus sativus L. collections on aluminum tolerance by A. B. Kurina, I. A. Kosareva, A. M. Artemyeva

“…In the absence of a rapid assessment methodology specialized for the species studied, a method is used to assess the aluminum resistance of cereals using an eriochrome cyanine R dye, which is based on the recovery or absence of restoration of mitotic activity of the seedlings roots subjected to shock exposure to aluminum. The effect of various concentrations on the vital activity of plants was revealed: a 66-mM concentration of AlCl3 · 6Н2О had a weak toxic effect on R. sativus accessions slowing down root growth; 83 mM contributed to a large differentiation of the small radish accessions and to a lesser extent for radish; 99 mM inhibited further root growth in 13.0 % of small radish accessions and in 7.3 % of radish and had a highly damaging effect. …”
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Acute Severe Anaphylaxis in Nepali Patients with Neurotoxic Snakebite Envenoming Treated with the VINS Polyvalent Antivenom by Sanjib Kumar Sharma, Emilie Alirol, Anup Ghimire, Suman Shrestha, Rupesh Jha, Surya B. Parajuli, Deekshya Shrestha, Surya Jyoti Shrestha, Amir Bista, David Warrell, Ulrich Kuch, Francois Chappuis, Walter Robert John Taylor

“…Principal signs of severe ARA were dyspnoea alone (n=5 patients), dyspnoea with wheezing (n=3), hypotension (n=3), shock (n=3), restlessness (n=3), respiratory/cardiorespiratory arrest (n=7), and early (n=1) and late laryngeal oedema (n=1); rash was associated with severe ARA in 10 patients. …”
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A study of the clinico-demographical profile of different dengue serotypes circulating in a Southern district of West Bengal, India by Sayani Bose, Feradica D Laloo, Partha Pratim Maity, Anirban Bhaduri

“…Background: Dengue virus (DENV) which is endemic in many tropical and subtropical areas around the world has four serotypes (DENV1, DENV2, DENV3and DENV4), this viral infection can either cause mild febrile illness Dengue fever or severe, such as Dengue hemorrhagic fever or Dengue Shock Syndrome. The dominant dengue serotypes in a region often change over time and the infecting serotypes are seen to have an impact on the clinical presentation and outcome of the patient. …”
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IMPACT OF ENERGY PRICES ON PRICES OF BASIC TOURISM SERVICES IN THE EURO AREA by Lachezar Borisov

“…The period of recovery has been accompanied by significant inflationary processes and a shock increase in the prices of energy products, further provoked by the war on the territory of Ukraine. …”
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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…Moreover, in a model of lethal LPS shock, NRTI administration prevented hypothermia and death. …”
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Primary Angioplasty in a Catastrophic Presentation: Acute Left Main Coronary Total Occlusion—The ATOLMA Registry by A. Gutiérrez-Barrios, L. Gheorghe, S. Camacho-Freire, F. Valencia-Serrano, D. Cañadas-Pruaño, G. Calle-Pérez, I. Alarcón de la Lastra, E. Silva, D. García-Molinero, A. Agarrado-Luna, R. Zayas-Ruedas, R. Vázquez-García, A. Serra

“…At admission, cardiogenic shock was present in 89% of patients, and cardiopulmonary resuscitation was required in 67.4%. …”
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Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy by Miao Shen, Jie Lu, Weiqi Dai, Fan Wang, Ling Xu, Kan Chen, Lei He, Ping Cheng, Yan Zhang, Chengfen Wang, Dong Wu, Jing Yang, Rong Zhu, Huawei Zhang, Yinqun Zhou, Chuanyong Guo

“…Hepatic ischemia-reperfusion (I/R) injury is a pivotal clinical problem occurring in many clinical conditions such as transplantation, trauma, and hepatic failure after hemorrhagic shock. Apoptosis and autophagy have been shown to contribute to cell death in hepatic I/R injury. …”
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Clinical outcomes of COVID-19 in patients with liver cirrhosis - a propensity-matched analysis from a multicentric Brazilian cohort by Luanna Silva Monteiro Menezes, Pedro Ferrari Sales da Cunha, Magda Carvalho Pires, Lucas Rocha Valle, Flávia Carvalho Cardoso Costa, Maria Angélica Pires Ferreira, Milton Henriques Guimarães Júnior, Saionara Cristina Francisco, Marcelo Carneiro, Daniel Vitório Silveira, Fernando Graça Aranha, Rafael Lima Rodrigues de Carvalho, Teresa Cristina de Abreu Ferrari, Milena Soriano Marcolino

“…They also had higher frequencies of admission in an intensive care unit (51.3% vs. 38.0%, p = 0.007), invasive mechanical ventilation (43.9% vs. 26.6%, p < 0.001), dialysis (17.9% vs. 11.1%, p = 0.038), septic shock (23.9% vs. 14.9%; p = 0.015) and institution of palliative care (19.7% vs. 7.4%; p < 0.001). …”
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Establishment and validation of predictive model of ARDS in critically ill patients by Senhao Wei, Hua Zhang, Hao Li, Chao Li, Ziyuan Shen, Yiyuan Yin, Zhukai Cong, Zhaojin Zeng, Qinggang Ge, Dongfeng Li, Xi Zhu

“…The final model included gender, Lung Injury Prediction Score (LIPS), Hepatic Disease, Shock, and combined Lung Contusion. Based on the AUC and DCA in the validation group, the logistic model demonstrated excellent performance, achieving an AUC of 0.836 (95% CI: 0.762–0.910). …”
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