Comportamiento de la sepsis en pacientes atendidos en el Hospital Pediátrico Paquito González (2009-2019) by Ariel Efrén Uriarte Méndez, Roberlan Cardoso Armas, Nicolás Ramón Cruz Pérez, Maira Valladares Vilches

“…Se revisaron las historias clínicas de los niños que, al ingreso en la Unidad de Cuidados Intensivos, se les diagnosticó sepsis, sepsis grave o shock séptico; entre enero de 2009 y diciembre de 2019. …”
Get full text

Exploring the antifungal potential of Cannabis sativa-derived stilbenoids and cannabinoids against novel targets through in silico protein interaction profiling by Kevser Kübra Kırboğa, Aman Karim, Ecir Uğur Küçüksille, Mithun Rudrapal, Johra Khan, Raghu Ram Achar, Ekaterina Silina, Natalia Manturova, Victor Stupin

“…The proteins investigated included Glycosylphosphatidylinositol (GPI), Enolase, Mannitol-2-dehydrogenase, GMP synthase, Dihydroorotate dehydrogenase (DHODH), Heat shock protein 90 homolog (Hsp90), Chitin Synthase 2 (CaChs2), and Mannitol-1-phosphate 5-dehydrogenase (M1P5DH), all of which play crucial roles in fungal survival and pathogenicity. …”
Get full text

Determination of Electrolytes in Critical Illness Patients at Different pH Ranges: Whom Shall We Believe, the Blood Gas Analysis or the Laboratory Autoanalyzer? by Christopher Hohmann, Roman Pfister, Kathrin Kuhr, Julia Merkle, Julian Hinzmann, Guido Michels

“…All patients suffered an infarct-related cardiogenic shock and were intubated and not under therapeutical hypothermia at the time of blood collection. …”
Get full text

SUGT1 is a prognostic biomarker and is associated with immune infiltrates in ovarian cancer by Linyan Ge, Xiu Liu, Lingyan Zhang, Jiaren Zhang, Guanghui Song

“…The SGT1 homolog (SUGT1) protein, which interacts with heat shock protein 90 and is essential for the G1/S and G2/M transitions, was formerly thought to be a cancer promoter, but its precise role in OC remains unknown. …”
Get full text

Potential Virulence and Survival of Acid-Resistant Bacillus cereus KS100Bc Isolated from Foodservice Establishments in Korea by Seung Min Kim, Daekeun Hwang, Hyun Jung Kim

“…The transcriptional profiles were compared to examine the differences in the response to acid shock. KS100Bc exhibited increased expression of genes associated with pH homeostasis, oxidative response, metabolic rearrangements, and general stress response with over twofold (P value < 0.05) relative gene expression compared with the type strain. …”
Get full text

A Small Increase in Serum Creatinine within 48 h of Hospital Admission Is an Independent Predictor of In-Hospital Adverse Outcomes in Patients with ST-Segment Elevation Myocardial... by Jiajia Zhu, Wenxian Liu, Jiang Li, Changsheng Ma, Dong Zhao

“…Secondary outcomes included the incidence of massive hemorrhage, in-hospital death, atrial fibrillation, heart failure, cardiogenic shock, cardiac arrest, and stroke. Logistic regression analysis was used to evaluate associations between a small increase in Scr within 48 h of hospitalization (>0.1 to <0.3 mg/dl) and MACE or massive hemorrhage during hospitalization. …”
Get full text

Development and assessment of a mortality risk prediction nomogram model for pneumocystis disease in ICU within 28 days by Yiru Weng, Tingting Zhou, Honghua Ye

“…Five variables—the history of malignant tumors, Lods scores, Oasis scores, and complications of shock and severe renal injury—were eventually included in the entire sample after screening. …”
Get full text

Evaluation of cellular and physiological alterations of cells from Mytilus galloprovincialis exposed to benzisothiazolinone by Federica Impellitteri, Kristian Riolo, Giorgia Zicarelli, Miriam Porretti, Cristiana Roberta Multisanti, Giuseppe Piccione, Alessia Giannetto, Caterina Faggio

“…The most significant results obtained from these tests were the reduction of viability of haemocytes at T2 of exposure to B2, a decrease of vitality in DG cells exposed to B1 during the T1, the significant alteration in the phagocytosis activity, the upregulation of Cu/ZnSOD gene, the inhibition of the CYPY1 gene expression and upregulation of the Heat shock protein 70 (Hsp70) gene following the BIT exposure. …”
Get full text

Environmental and economic drivers of subjective well-being: evaluating the effects of pollution, income growth, and income inequality in Pakistan by Saima Mehmood, Faiza Sajjad, Agha Amad Nabi, Ishfaq Ahmad, Imran Naseem, Khalid Zaman

“…The variance decomposition analysis suggests that PM2.5 is likely to exert the greatest variance shock on subjective well-being, followed by solid waste management and the country’s per capita income over the next 10 years. …”
Get full text

Incidence and Mechanisms of Coronary Perforations during Rotational Atherectomy in Modern Practice by Yen-Hsiang Wang, Wei-Jhong Chen, Yu-Wei Chen, Chih-Hung Lai, Chieh-Shou Su, Wei-Chun Chang, Chi-Yen Wang, Kae-Woei Liang, Tsun-Jui Liu, Wen-Lieng Lee

“…Most CPs could be treated conservatively, but prolonged profound shock predisposed to poor outcome. CPs caused by rotawire tip occurred in 18.2% of cases, inappropriately sized burrs in 18.2% of cases, and rotawire damage with subsequent transection and perforation in another 18.2% of cases. …”
Get full text

Association between spasticity and neuropathic pain in patients with multiple sclerosis by B. Afanasjeva, R. Balnytė

“…Patients usually experienced burning pain, in some cases sensation of painful freezing and electrical shock. Patients with spasticity had a higher incidence of neuropathic pain. …”
Get full text

Mesenchymal stem cell‐derived exosomes mitigate amyloid β‐induced retinal toxicity: Insights from rat model and cellular studies by Amanda Qarawani, Efrat Naaman, Rony Ben‐Zvi Elimelech, Michal Harel, Shahaf Sigal‐Dror, Tali Ben‐Zur, Tamar Ziv, Daniel Offen, Shiri Zayit‐Soudry

“…Proteomic analysis indicated a decrease in the retinal levels of heat‐shock proteins activated by pathogenic Aβ fibrils following AT‐MSC‐Exosome treatment. …”
Get full text

Interdisciplinary Team Pilot to Reduce Time to Administration of Piperacillin/Tazobactam in the Emergency Department at a Veterans Affairs Medical Center by DiVittorio MM, Fisher T, Steadman B, Cone B, Elfessi Z

“…Adults with suspected sepsis or possible septic shock should receive antimicrobials within 1 hour. …”
Get full text

Effectiveness of Steroid Pulse Therapy for Systemic Side Effects after Bacillus Calmette-Guérin Intravesical Instillation Therapy: A Series of Five Cases by Tatsuya Umemoto, Jun Naruse, Yukio Usui, Hidenori Zakoji, Hideshi Miyakita, Akira Miyajima

“…In the case of BCG sepsis, hemodialysis and mechanical ventilation were required because of septic shock and acute renal failure. Antituberculosis drugs (isoniazid, rifampicin, and ethambutol) were started promptly; however, no improvement was noticed. …”
Get full text

Microbiological Contamination of Food Raw Materials and Ready-To-Eat Foods: Analytical Review by Andrei S. Khishov, Tatiana V. Balagula, Olga I. Lavrukhina, Aleksey V. Tretyakov, Olga E. Ivanova, Elizaveta S. Kozeicheva

“…Composite products that cannot be succumbed to additional heat treatment need new technologies that minimize microbiological contamination, e.g., intensive cooling, shock freezing, electromagnetic processing, protective food coatings, etc. …”
Get full text

Preparation of NiCr/YSZ two-layered burn-resistant coating on γ-TiAl alloys based on plasma surface metallurgy and ion plating methods by Wei D.-B., Li M.-F., Zhou X., Li F.-K., Li S.-Q., Zhang P.-Z.

“…The average microhardness of NiCr/YSZ coating was raised by a factor of about 2 compared to the γ-TiAl substrate. The thermal shock test indicated that the composite structure had superior bonding strength and the defects such as metal droplets on the ceramic coating were the source of cracks. …”
Get full text

Early antibiotics administration reduces mortality in sepsis patients in tertiary care hospital by Suramath Isaranuwatchai, Jirawat Buppanharun, Thamonwan Thongbun, Kaewklao Thavornwattana, Monprach Harnphadungkit, Taweegrit Siripongboonsitti

“…However, the appropriate timing of antibiotics remains a controversial issue, especially in patients without septic shock. Here, we reported the outcomes of early antibiotic administration within one hour from the time of infection suspicion in a tertiary care hospital. …”
Get full text

Microplastic exposure induces HSP90α secretion and aggravates asthmatic airway remodeling via PI3K-Akt-mTOR pathway by Mingming Xu, Jiyuan Chen, Lin Gao, Shaoxi Cai, Hangming Dong

“…There are several cytokines involved in the inflammatory response of asthma. Heat shock protein 90α(HSP90α) is one of cytokines involving in inflammation which is a member of the HSPs family. …”
Get full text

Black Hole Supernovae, Their Equation of State Dependence, and Ejecta Composition by Oliver Eggenberger Andersen, Evan O’Connor, Haakon Andresen, André da Silva Schneider, Sean M. Couch

“…Recent literature on core-collapse supernovae suggests that a black hole (BH) can form within ∼1 s of shock revival, while still culminating in a successful supernova. …”
Get full text

Factores pronósticos de la mortalidad de pacientes con reintervenciones de cirugía abdominal en Unidad de Cuidados Intensivos by Yordany Quintana Dorta, Angel Antonio Urbay Ruiz, Elaine Teresa Gutiérrez Pérez, Mabel Merlán Martínez, Leyla Aurora Rodríguez Pedraza, Isabel Vázquez Curdis

“…Conclusiones: Los factores pronósticos para la mortalidad de pacientes con reintervenciones quirúrgicas abdominales fueron: el Shock séptico, la Neumonía, la conducta antimicrobiana empírica y la Hipertensión Arterial como comorbilidad. …”
Get full text