TNF-α as a Therapeutic Target in Acute Pancreatitis — Lessons from Experimental Models by Giuseppe Malleo, Emanuela Mazzon, Ajith K. Siriwardena, Salvatore Cuzzocrea

“…A considerable body of experimental evidence suggests that tumor necrosis factor (TNF)-α plays a major role in several aspects of inflammation and shock. In particular, it is pivotal in many detrimental effects of acute pancreatitis, and it represents a major determinant of the systemic progression and end-organ damage (such as acute lung injury and liver failure) of this pathologic condition. …”
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The Effects of Circadian Rhythm on Lead-Induced Toxicity in the DBC1.2 Olfactory Dark Basal Cell Line by Teru Kamogashira, Shu Kikuta, Tatsuya Yamasoba

“…Methods: The DBC1.2 olfactory dark basal cell line was used. Dexamethasone shock was used to reset the circadian clock 24 h (Group 1) and 36 h (Group 2) after seeding. …”
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Species-Related Differences in the Proteome of Rat and Human Pancreatic Beta Cells by G. A. Martens

“…Human cells also expressed more heat shock proteins and radical scavenging systems: apart from SOD2, they expressed high levels of H2O2-scavenger peroxiredoxin 3 (PRDX3), confirmed by microarray, Western blotting, and microscopy. …”
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Exergy Analysis in Hydrogen-Air Detonation by Abel Rouboa, Valter Silva, Nuno Couto

“…The main goal of this paper is to analyze the exergy losses during the shock and rarefaction wave of hydrogen-air mixture. …”
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Banking and Fiscal Unions in the EU: What is More Relevant? by A. N. Tsibulina

“…At the same time sovereign debt crises in a number of member-states, on the one hand, showed lack of an effective EU-wide system of control over a fiscal discipline and, on the other hand raised questions about lack of any system of fiscal transfers to countries hit by a negative shock. The New Banking and Fiscal unions have been designed to withshand those challenges. …”
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Fatal Plasmodium falciparum, Clostridium perfringens, and Candida spp. Coinfections in a Traveler to Haiti by Gillian L. Genrich, Julu Bhatnagar, Christopher D. Paddock, Sherif R. Zaki

“…When a patient presents with P. falciparum and shock and is unresponsive to malaria treatment, secondary infections should be suspected to initiate appropriate treatment.…”
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Adaptive Numerical Method for Approximation of Traffic Flow Equations by Neda Najafzadeh, Saeid Abbasbandy, Elyas Shivanian

“…Because these models are among the stiff and shocking problems, theoretical methods do not give good answers to these problems. …”
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The Importance of the Monitoring of Resuscitation with Blood Transfusion for Uterine Inversion in Obstetrical Hemorrhage by Seishi Furukawa, Hiroshi Sameshima

“…We extracted data for six patients diagnosed with uterine inversion concerning resuscitation. Results. The shock index on admission of the six patients was 1.6 or more on admission. …”
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Global inflation: modern determinism and challenges for policy by Ye. N. Smirnov

“…The article studies global inflation determinants, causing it in recent decades and at the present stage under the influence of cascading shocks in world economy and financial system.   The relevance of the problems summarized and analyzed in the article is explained by the significant risks of the inflation duration at the present stage, which is affected by an increasing number of shocks from demand, supply, and global financial system. …”
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Kidney and Urinary Tract Involvement in Kawasaki Disease by Toru Watanabe

“…These disorders include pyuria, prerenal acute kidney injury (AKI), renal AKI caused by tubulointerstitial nephritis (TIN), hemolytic uremic syndrome (HUS), and immune-complex mediated nephropathy, renal AKI associated with either Kawasaki disease shock syndrome or unknown causes, acute nephritic syndrome (ANS), nephrotic syndrome (NS), renal tubular abnormalities, renal abnormalities in imaging studies, and renal artery lesions (aneurysms and stenosis). …”
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Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case Report by I Gusti Agung Ayu Andra Yusari, Ida Ayu Sri Wijayanti, Ketut Widyastuti, I Made Oka Adnyana

“…We present a case of a female patient, 28 years old, with attacks of right-sided severe pain in the face, which felt like burning and electric shock. The pain began after hospitalization due to a brainstem hemorrhagic stroke in the right pons and mesencephalon, and the pain persisted for several months. …”
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Nineteen years retrospective analysis of epidemiology, antifungal resistance and a nomogram model for 30-day mortality in nosocomial candidemia patients by Zhang Dai, Xuhong Lan, Minjing Cai, Yunhui Liao, Jingwen Zhang, Naifang Ye, Xinxin Lu, Jiajia Wang, Yun Xiao, Yan Zhang, Yihui Yao, Xianming Liang

“…Five independent factors included Candida albicans, decreased albumin, multiple organ dysfunction syndrome, solid tumor and septic shock were adopted in a nomogram for 30-days mortality of candidemia. …”
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Risk factors associated with mortality and pathogen characteristics of bloodstream infection-induced severe sepsis in the pediatric intensive care unit: a retrospective cohort stud... by Jian Chen, Jian Chen, Haixin Huang, Ruichen Zhang, Yueqiang Fu, Chunmei Jing

“…BackgroundBloodstream infection (BSI)-induced severe sepsis is a common cause of mortality, frequently resulting in septic shock and multiple organ dysfunction syndrome (MODS). …”
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Coronavirus Disease 2019-Related Multisystem Inflammatory Syndrome in Children: A Systematic Review and Meta-Analysis by Ji-Gan Wang, Zhi-Juan Zhong, Meng Li, Jun Fu, Yu-Heng Su, You-Min Ping, Zi-Ji Xu, Hao Li, Yan-Hao Chen, Yu-Li Huang

“…The incidences of PICU hospitalization or with shock were 72.79% and 55.68%, respectively. The mortality rate was 1.00%. …”
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Cardiovascular outcomes in long COVID-19: a systematic review and meta-analysis by Ting Zhang, Zhimao Li, Qimin Mei, Joseph Harold Walline, Zhaocai Zhang, Yecheng Liu, Huadong Zhu, Bin Du

“…Long COVID-19 was associated with a higher risk of thromboembolic disorders [HR 3.12 (1.60, 6.08)], coronary heart disease [HR 1.61 (1.13, 2.31)], stroke [HR 1.71 (1.07,2.72)], arrhythmia [HR 1.60 (1.13, 2.26)], cardiomyopathy [HR 1.71 (1.12, 2.61)], myocarditis [HR 6.11 (4.17,8.94)], hypertension [HR 1.70 (1.56, 1.85)], heart failure [HR 1.72 (1.15,2.59)] and cardiogenic shock [HR 2.09 (1.53,2.86)] compared to non-COVID-19 controls. …”
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The Confluence of Stereotactic Ablative Radiotherapy and Tumor Immunology by Steven Eric Finkelstein, Robert Timmerman, William H. McBride, Dörthe Schaue, Sarah E. Hoffe, Constantine A. Mantz, George D. Wilson

“…Herein, we will discuss how SABR can induce cellular expression of MHC I, adhesion molecules, costimulatory molecules, heat shock proteins, inflammatory mediators, immunomodulatory cytokines, and death receptors to enhance antitumor immune responses.…”
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Intermittent Flow Regimes in a Transonic Fan Airfoil Cascade by J. Lepicovsky, E. R. McFarland, R. V. Chima, V. R. Capece, J. Hayden

“…Experimental results revealed that, at a large incidence angle, a range of transonic inlet Mach numbers exist where the leading-edge shock-wave pattern was unstable. Flush-mounted, high-frequency response pressure transducers indicated large local jumps in the pressure in the leading edge area, which generates large intermittent loading on the blade leading edge. …”
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X-Ray-Based 3D Histopathology of the Kidney Using Cryogenic Contrast-Enhanced MicroCT by Arne Maes, Onno Borgel, Clara Braconnier, Tim Balcaen, Martine Wevers, Rebecca Halbgebauer, Markus Huber-Lang, Greet Kerckhofs

“…This optimized protocol showed to be highly sensitive, allowing to detect small pathology-induced microstructural changes in a mouse model of mild trauma-related acute kidney injury after thorax trauma and hemorrhagic shock. In summary, we demonstrated that cryo-CECT is an effective 3D histopathological tool that allows to enhance our understanding of kidney tissue microstructure and their related function.…”
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Commercial Cannabinoid Oil-Induced Stevens-Johnson Syndrome by Han Y. Yin, Nicholas Hadjokas, Kanish Mirchia, Robert Swan, Samuel Alpert

“…She was otherwise treated with supportive therapy in the intensive care burn unit and ultimately passed away from septic shock. Conclusion. In this case, we described an unusual drug-induced SJS from a commercial, non-FDA-regulated cannabis product. …”
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Non-Permanent Transcatheter Proximal Renal Artery Embolization for a Grade 5 Renal Injury with Delayed Recanalization and Preserved Renal Parenchymal Enhancement by Abhishek Jairam, Bradley King, Zachary Berman, Gerant Rivera-Sanfeliz

“…We present the unique case of a patient who presented in hemorrhagic shock following a major trauma that resulted in a grade 5 renal injury treated with complete renal artery embolization using Gelfoam, resulting in hemodynamic stabilization. …”
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