Comparison of the efficacy and safety of Landiolol and Esmolol in critically ill patients: a propensity score-matched study by Xiang Si, Hao Yuan, Rui Shi, Wenliang Song, Jiayan Guo, Jinlong Jiang, Tao Yang, Xiaoxun Ma, Huiming Wang, Minying Chen, Jianfeng Wu, Xiangdong Guan, Xavier Monnet

“…Patients in the Landiolol group were observed to experience shorter HLOS than patients in the Esmolol group (26.5 [13.0, 42.0] vs 30.0 [17.0, 47.2] days, respectively, p = 0.044) and ICULOS (4.9 [2.8, 10.0] vs.6.7 [3.4, 13.1] days, respectively, p = 0.011). …”
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Predictive marker for response to trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer patients by Toshiaki Takahashi, Kunitoshi Shigeyasu, Yoshitaka Kondo, Sho Takeda, Hibiki Umeda, Kazuya Moriwake, Masashi Kayano, Yuya Sakurai, Shunsuke Nakamura, Masafumi Takahashi, Kaori Nitta, Kazuhiro Yoshida, Yuki Matsumi, Hiroyuki Michiue, Hideki Yamamoto, Hiroyuki Kishimoto, Fuminori Teraishi, Ryohei Shoji, Nobuhiko Kanaya, Hajime Kashima, Yoshihiko Kakiuchi, Shinji Kuroda, Shunsuke Kagawa, Toshiyoshi Fujiwara

“…Among the participants, those with a high NLR had a shorter PFS (p = 0.0395). Moreover, high ADAR1 expression was associated with longer PFS (p = 0.0151). …”
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Effect of Electroacupuncture at Shuigou Acupoint on L-type Voltage-gated Calcium Channels in hippocampal CA1 region of MCAO rats by Da LONG, Ling CHEN, Yu YAO, Mingan ZENG

“…There was no statistically significant difference in current amplitude of the L-type voltage-gated calcium channels between the non-acupoint group and the control group(<italic>P</italic>&gt;0.05).(3)The mean opening time constant of the L-type voltage-gated calcium channels in the Shuigou group was significantly shorter than that in the control group and the non-acupoint group respectively(<italic>P</italic>&lt;0.05). …”
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A semantic strength and neural correlates in developmental dyslexia by Sladjana Lukic, Sladjana Lukic, Sladjana Lukic, Fei Jiang, Maria Luisa Mandelli, Maria Luisa Mandelli, Ting Qi, Sarah M. Inkelis, Sarah M. Inkelis, Emily Rosenthal, Emily Rosenthal, Zachary Miller, Zachary Miller, Emma Wellman, Emma Wellman, Silvia A. Bunge, Silvia A. Bunge, Silvia A. Bunge, Maria Luisa Gorno-Tempini, Maria Luisa Gorno-Tempini, Christa Watson Pereira, Christa Watson Pereira

“…Differential dynamic rs-fMRI connectivity (shorter average dwell time and greater brain state switches) was observed between the high and average groups in a large-scale bilateral frontal-temporal-occipital network.DiscussionThese data demonstrate that a subgroup of children with dyslexia perform above average on semantic fluency tasks and their performance is strongly linked to distinct psycholinguistic patterns and differences in a task-free resting-state brain network, which includes regions previously implicated in semantic processing. …”
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Effect of Traditional Chinese Medicine enema combined with injection via gastric tube in the treatment of gastrointestinal dysfunction in ICU patients (中药胃肠联合治疗ICU患者胃肠功能障碍的效果观察)... by ZHONG Yongjian (钟永建)

“…The ICU hospitalization time of the observation group was shorter than that in the control group (P＜0. 05). …”
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Effect of Traditional Chinese Medicine nursing combined with continuous nebulization in nursing of elderly patients undergoing tracheostomy (中医护理联合持续雾化吸入在老年气管切开患者护理中的应用效果观察)... by HUANG Ning (黄宁)

“…The incidence of high sputum viscosity, respiratory tract irritation symptoms, airway mucosal damage and sputum blockage were observed during follow-up. Results Shorter duration of lung infection and retention time of tracheotomy catheter were observed in the study group than those in the control group (P<0. 05). …”
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Inter-pregnancy interval and uterine rupture during a trial of labour after one previous caesarean delivery and no previous vaginal births: a retrospective population-based cohort... by Pejman Adily, Travis Bettison, Mark Lauer, Rajit Narayan, Adam Mackie, Hala Phipps, Vincenzo Berghella, Marjan M. Haghighi, Katelyn Perren, George Johnson, Bradley de Vries

“…Other factors associated with uterine rupture included older maternal age, shorter maternal height, more advanced gestational age (from 35 to 43 weeks), and heavier birthweight. …”
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Blinking characteristics analyzed by a deep learning model and the relationship with tear film stability in children with long-term use of orthokeratology by Yue Wu, Siyuan Wu, Yinghai Yu, Yinghai Yu, Xiaojun Hu, Ting Zhao, Yan Jiang, Bilian Ke

“…Notably, the ortho-K group exhibited shorter first (11.75 ± 7.42 s vs. 14.87 ± 7.93 s, p = 0.030) and average non-invasive tear break-up times (NIBUT) (13.67 ± 7.0 s vs. 16.60 ± 7.24 s, p = 0.029) compared to the control group. …”
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Residence-based disparities of composite index of anthropometric failures in East African under five children; multivariate decomposition analysis by Aznamariam Ayres, Yawkal Tsega, Abel Endawkie, Shimels Derso Kebede, Eyob Tilahun Abeje, Ermias Bekele Enyew, Chala Daba, Lakew Asmare, Amare Muche, Fekade Demeke Bayou, Mastewal Arefaynie, Asnakew Molla Mekonen, Abiyu Abadi Tareke, Awoke Keleb, Kaleab Mesfin Abera, Natnael Kebede, Endalkachew Mesfin Gebeyehu

“…There is substantial evidence that the majority of the rural children under-5 years old have composite index of anthropometric failure than the urban counter parts. Hence, identifying the main contributors of these disparities will help health policy makers, program designers and implementers for the reduction of composite index of anthropometric failures in children under-5 years old in the study areas. …”
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Optimization of salinity range for rearing glass eel Anguilla bicolor bicolor by Ade Yulita Hesti Lukas, Daniel Djokosetiyanto, Tatag Budiardi, Agus Oman Sudrajat, Ridwan Affandi

“…ABSTRACT   Fasting is one of a method that used for measured growth of fish in a shorter period of time. This study was aimed to determine the optimum range of salinity for improve the survival and growth of glass eel Anguilla bicolor bicolor. …”
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Cross-Gendering the Racial Memory by Marlon B. Ross

“…Gaines chooses a woman as his medium/subject both to envelope the image of the gigantic black feminine as black nationalist icon and to counter that image in favor of a conscientious black nation within a bloody white nation, the black (wo)man as the purifying conscience of the historically compromised American nation-state. …”
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RET inhibition overcomes resistance to combined CDK4/6 inhibitor and endocrine therapy in ER+ breast cancer by Charlotte K. Kindt, Sidse Ehmsen, Sidse Ehmsen, Sidse Ehmsen, Sofie Traynor, Benedetta Policastro, Nikoline Nissen, Mie K. Jakobsen, Monique F. Hundebøl, Lene E. Johansen, Martin Bak, Elsa Arbajian, Johan Staaf, Henrik J. Ditzel, Henrik J. Ditzel, Henrik J. Ditzel, Carla L. Alves

“…We further observed a shorter median survival to combined CDK4/6i and endocrine therapy in patients with RET-positive compared to RET-negative tumors, but this difference did not reach statistical significance.ConclusionsOur findings show that RET is overexpressed in ER+ metastatic breast cancer resistant to combined CDK4/6i and endocrine therapy, rendering RET inhibition a promising therapeutic approach for patients who experience disease progression on combined CDK4/6i and endocrine therapy.…”
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Comparison on the effect of different dressings on poor wound healing after surgery via posterior midline approach (不同敷料对后正中手术入路切口愈合不良的影响差异研究)... by ZHANG Tingting (张婷婷), ZHANG Hongyang (张宏扬), ZHU Ruifang (朱瑞芳)

“…Results The healing time of incision grade A in the intervention group was significantly shorter than that in the control group［(12. 02±1. 69) days vs. (15. 90±2. 30) days］, with a statistically significant difference (P＜0. 01). …”
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The PANORAMIC Survey: Pure Parallel Wide Area Legacy Imaging with JWST/NIRCam by Christina C. Williams, Pascal A. Oesch, Andrea Weibel, Gabriel Brammer, Aidan P. Cloonan, Katherine E. Whitaker, Laia Barrufet, Rachel Bezanson, Rebecca A. A. Bowler, Pratika Dayal, Marijn Franx, Jenny E. Greene, Anne Hutter, Zhiyuan Ji, Ivo Labbé, Sinclaire M. Manning, Michael V. Maseda, Mengyuan Xiao

“…The ≳6-filter strategy yields remarkably good photometric redshift performance, achieving similar median scatter and outlier fraction as CANDELS ( σ _NMAD ∼ 0.07; η ∼ 0.2), enabling a wealth of science across redshift without need for follow-up or ancillary data. …”
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Study protocol for a randomized controlled trial of Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: the PROMIZING study by Karen J. Bosma, Claudio M. Martin, Karen E. A. Burns, Jordi Mancebo Cortes, Juan Carlos Suárez Montero, Yoanna Skrobik, Kevin E. Thorpe, Andre Carlos Kajdacsy-Balla Amaral, Yaseen Arabi, John Basmaji, Gaëtan Beduneau, Francois Beloncle, Guillaume Carteaux, Emmanuel Charbonney, Alexandre Demoule, Martin Dres, Vito Fanelli, Anna Geagea, Ewan Goligher, François Lellouche, Tommaso Maraffi, Alain Mercat, Pablo O. Rodriguez, Jason Shahin, Stephanie Sibley, Savino Spadaro, Katerina Vaporidi, M. Elizabeth Wilcox, Laurent Brochard, On behalf of the Canadian Critical Care Trials Group and, the REVA Network

“…Methods The objective of this multi-centre randomized controlled trial (RCT) is to determine if, for patients with acute respiratory failure, ventilation with PAV+ will result in a shorter time to successful extubation than with PSV. …”
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Application of finger-pressing on Tiantu acupoint to induce cough in postoperative patients with early-stage lung cancer (指压天突穴引咳法在早期肺癌术后患者中的应用)... by BIAN Guanjun (边冠军), ZHANG Chunmei (张春梅), LIU Lifeng (刘丽峰)

“…The time (h) to cough up the first sputum after nebulization on the first postoperative day was shorter in the observation group (1. 73±0. 81) than in the control group (3. 02±0. 88), with a significant difference(P＜0. 01). …”
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Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors by Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio, Julien Taieb, David Tougeron, Margherita Ambrosini, Michael J Overman, Alice Boilève, Lisa Salvatore, Rosine Guimbaud, Priya Jayachandran, Frank A Sinicrope, Thibault Mazard, Javier Ros, Vincenzo Nasca, Simon Pernot, Emily Alouani, Marie Decraecker, Emilie Hafliger, Pauline Parent

“…Pivotal trials have fixed a maximum ICI duration of 2 years, without a compelling rationale. A shorter treatment duration has the potential to improve patients' quality of life and reduce both toxicity and cost without compromising efficacy. …”
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‘Dynamic zero-COVID’ policy and viral clearance during an omicron wave in Tianjin, China: a city-wide retrospective observational study by Qi Wu, Yan Xie, Tao Cheng, Junping Wu, Wentao Jiang, Lixia Shi, Xiaolong Liu, Yu Hu, Yahui Feng, Hongxia Shao, Xiaowen Gong, Zhen Song, Saibing Qi, Xueou Liu, Qiujin Shen, Junren Chen

“…It might be possible to predict in advance which cases will require shorter periods of isolation based on their clinical features.…”
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Phenotypic diversity of CTCs and tdEVs in liquid biopsies of tumour-draining veins is linked to poor prognosis in colorectal cancer by Stefan A. Cieslik, Andrés G. Zafra, Christiane Driemel, Monica Sudarsanam, Jan-Philipp Cieslik, Georg Flügen, Levent Dizdar, Andreas Krieg, Sascha Vaghiri, Hany Ashmawy, Stephen Fung, Miriam Wilms, Leon W. M. M. Terstappen, Afroditi Nanou, Hans Neubauer, Nuh N. Rahbari, Wolfram T. Knoefel, Nikolas H. Stoecklein, Rui P. L. Neves

“…Furthermore, increased diversity in CTC and tdEV phenotypes was significantly associated with shorter survival, validating the prognostic relevance of the SD-diversity metric. …”
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Several factors that predict the outcome of large B‐cell lymphoma patients who relapse/progress after chimeric antigen receptor (CAR) T‐cell therapy can be identified before cell a... by Alice Sýkorová, František Folber, Kamila Polgárová, Heidi Móciková, Juraj Ďuraš, Kateřina Steinerová, Aleš Obr, Adriana Heindorfer, Miriam Ladická, Ľubica Lukáčová, Erika Čellárová, Ivana Plameňová, David Belada, Andrea Janíková, Marek Trněný, Tereza Jančárková, Vít Procházka, Andrej Vranovský, Margaréta Králiková, Jan Vydra, Lukáš Smolej, Ľuboš Drgoňa, Martin Sedmina, Eva Čermáková, Robert Pytlík

“…The risk factors for a shorter PFS‐2 (n = 39) included: CRP > limit of the normal range (LNR) before LD, albumin < LNR and ECOG PS > 1 at R/P. …”
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