Preoperative Education is Associated with Adherence to Downstream Components and Outcomes in a Colorectal Surgery Enhanced Recovery Program by Bayley A. Jones, MD, Joshua Richman, MD, PhD, Michael Rubyan, PhD, MPH, Lauren Wood, MSPH, Alfonsus Adrian H. Harsono, MD, MSPH, Wendelyn Oslock, MD, MBA, Nathan English, MBChB, Burkely P. Smith, MD, Robert Hollis, MD, MSPH, Larry R. Hearld, PhD, Isabel Scarinci, PhD, MPH, Daniel I. Chu, MD, MSPH

“…High-level ERP adherence was 13.4% higher (P < 0.01) and LOS was 2.0 days shorter (P < 0.001) for those who received preoperative education. …”
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Stellar X-Ray Variability and Planetary Evolution in the DS Tucanae System by George W. King, Lía R. Corrales, Vincent Bourrier, Leonardo A. Dos Santos, Lauren Doyle, Baptiste Lavie, Gavin Ramsay, Peter J. Wheatley

“…The variation in our flux measurements across the four visits is also consistent with the scatter in empirical stellar X-ray relationships with Rossby number. …”
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Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer’s disease by Jared M. Fine, Jacob Kosyakovsky, Tate T. Bowe, Katherine A. Faltesek, Benjamin M. Stroebel, Juan E. Abrahante, Michael R. Kelly, Elizabeth A. Thompson, Claire M. Westby, Kiley M. Robertson, William H. Frey, Leah R. Hanson

“…As an antioxidant iron chelator, its mechanisms are multimodal, involving the binding of brain iron and the consequent engagement of several pathways to counter pathogenesis across multiple diseases. We and other research groups have shown that IN DFO rescues cognitive impairment in several rodent models of Alzheimer Disease (AD).MethodsThis study was designed to probe dosing regimens to inform future clinical trials, while exploring mechanisms within the intracerebroventricular (ICV) streptozotocin (STZ) model.ResultsFive weeks of daily IN dosing of Long Evans rats with 15 μL of a 1% (0.3 mg), but not 0.1% (0.03 mg), solution of DFO rescued cognitive impairment caused by ICV STZ administration as assessed with the Morris Water Maze (MWM) test of spatial memory and learning. …”
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Construction and validation of a prognostic model for NK/T-cell lymphoma based on random survival forest algorithm by HUANG Zhen, HUANG Zhen, WU Yazhou

“…Both models effectively stratified the patients into poor and favorable prognosis groups, with the OS of patients in the poor prognosis group being significantly shorter than that of the favorable prognosis group (P<0.000 1). …”
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Effect of Task Oriented Training on Gross Motor Dysfunction for Children with Cerebral Palsy： A Meta-Analysis by LI Yang, CHEN Ying, ZHU Xiangyu, SHI Jiehong, FENG Yuan, WU Wenlei, FU Ruochen

“…Meta-analysis results showed that, compared with the control group, the GMFM scale standing score in the experimental group was higher [<italic>SMD</italic>=0.78, 95% <italic>CI</italic> (0.59, 0.98), <italic>P</italic>&lt;0.000 01], walking, running and jumping scores was higher [<italic>SMD</italic>=4.05, 95% <italic>CI</italic> (2.06, 6.05), <italic>P</italic>&lt;0.000 01], GMFM scale overall score was higher [<italic>SMD</italic>=10.23, 95% <italic>CI</italic> (7.00, 13.46), <italic>P</italic>&lt;0.000 01], PEDI score was higher [<italic>SMD</italic>=6.87, 95% <italic>CI</italic> (4.19, 9.54), <italic>P</italic>&lt;0.000 01], TUG test time was shorter [<italic>SMD</italic>=-3.17, 95% <italic>CI</italic> (-4.84, -1.49), <italic>P</italic>=0.000 2], and BBS score was higher [<italic>SMD</italic>=5.26, 95% <italic>CI</italic> (4.05, 6.46), <italic>P</italic>&lt;0.000 01].ConclusionTask oriented training can effectively improve the gross motor function (such as walking, running, jumping, etc.) of children with cerebral palsy, shorten the TUG test time, and improve their balance function and activities of daily living.…”
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Mortality of elder financial and psychological abuse victims in rural Malaysia: a prospective cohort study by Raudah Mohd Yunus, Farizah Hairi, Noran N Hairi, Wan Yuen Choo, Sajaratulnisah Othman, Rajini Sooryanarayana, Norliana Ismail, Sharifah Nor Ahmad, Inayah Abdul Razak, Devi Peramalah, Awang Bulgiba Awang Mahmud, Halima B Awang, Siti Zaharah Jamaludin, Jamali Samsuddin, Mohammad Mafrukhin Mokhtar, Syed Mohd Fauzi, Zainudin Mohd Ali

“…Kaplan-Meier curves showed shorter survival among abuse victims, but Cox regression found no significant impact of financial and psychological abuse on mortality risk (HR 1.05, 95% CI 0.78 to 1.41). …”
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Prognostic and Clinicopathological Significance of MUC Family Members in Colorectal Cancer: A Systematic Review and Meta-Analysis by Chao Li, Didi Zuo, Tao Liu, Libin Yin, Chenyao Li, Lei Wang

“…Furthermore, a high level of MUC1 expression (HR=1.99; 95% CI, 0.99–3.99; P=0.05) was associated with shorter DFS/RFS. However, patients with a low level of MUC2 tumors showed better DFS/RFS than patients with a high level of MUC2 tumors (HR=0.71; 95% CI, 0.49–1.04; P=0.08; P=0.0.009, I2=67%) and MUC5AC expression (HR=0.56; 95% CI, 0.38–0.82; P=0.003) was associated with longer DFS/RFS. …”
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Uncovering the role of tumor cGAS expression in predicting response to PD-1/L1 inhibitors in non-small cell lung cancer by Yuichi Ozawa, Yasuhiro Koh, Ryota Shibaki, Yuhei Harutani, Hiroaki Akamatsu, Atsushi Hayata, Takeya Sugimoto, Yuka Kitamura, Junya Fukuoka, Masanori Nakanishi, Nobuyuki Yamamoto

“…Unexpectedly, patients with high cGAS (H-score ≥ 220) demonstrated significantly shorter progression-free survival (PFS) of PD-1/L1 inhibitors when the PD-L1 TPS was high (median PFS: 143 days vs. not reached; p = 0.028); PFS at 18 months was 7% and 53% in the high and low cGAS groups, respectively while STING expression did not impact PFS. …”
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THC degradation does not impair the accuracy of THC doses aerosolized by the metered-dose SyqeAir inhaler: a 24-month stability trial by Joshua Aviram, Daniella Atzmony, Anna Frenklakh, Asaf Kroll, Ilana Zaks, Arno Hazekamp

“…Storage at 30°C revealed a steeper change in phytocannabinoid concentrations within an even shorter period. Despite the significant change of relative cannabinoid composition within the cartridge, the actual THC dose present in the aerosol remained relatively stable throughout this period and within the dosage range of 500mcg±25% required for pharmaceutical-grade inhalers. …”
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Inferior outcome of stand-alone short versus long tibial stem in revision total knee arthroplasty. A retrospective comparative study with minimum 2 year follow-up by Abdelatif Elsayed Ahmed, Abu Mukh Assala, Elsaid Ahmed Nady Saleh, Youssef Ahmed Omar, Foissey Constant, Servien Elvire, Lustig Sebastien

“…Time-to-re-revision was shorter in SS group and occurred at a mean of 3.1 years, while LS failed at a mean of 5.1 years (p < 0.001). …”
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Evaluation of the Back-in-Action test Battery In Uninjured High School American Football Players by Marcel Rohde, Alina Ruhlemann, Andre Busch, Ulrich Grunwald, Marcus Jaeger, Constantin Mayer

“… # Methods Fifty-three healthy male American football players underwent a functional assessment using the “Back-in-action” test battery evaluating agility, speed (Parkour-Jumps and Quick-Feet test), balance (using a PC based balance board), and power (Counter-Movement-Jump [CMJ]) as objective measures. …”
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Feasibility of teleyoga for people with post COVID-19 condition– a mixed method design by Marie Lundberg, Leonie Klompstra, Lotti Orwelius, Mirjam Schimanke, Cecilia Olsson, Anna Strömberg

“…Conclusion Adherence to the online yoga sessions was quite low and might be improved with shorter yoga sessions. Online yoga was safe, but some participants experienced an increase in symptoms. …”
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Effects of physical exercise on anxiety depression and emotion regulation in children with attention deficit hyperactivity disorder: a systematic review and meta-analysis by Yagang Song, Shuqi Jia, Xing Wang, Aiwei Wang, Tao Ma, Shufan Li, Jiwei Chen, Zhaohui Guo, Feng Ding, Yuxi Ren, Man Qin

“…Exercise programs featuring mixed modalities, longer duration, moderate to high frequencies, shorter duration, and low intensity yielded the most significant improvements in emotional regulation.ConclusionsResearch demonstrates that physical exercise mitigates anxiety and depression and improves emotional regulation in children with ADHD. …”
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Inspiratory muscle training facilitates liberation from mechanical ventilation in subacute critically ill patients—a randomized controlled trial by Shu-Jane Wang, Tien-Pei Fang, Tien-Pei Fang, Daniel D. Rowley, Nan-Wei Liu, Jui-O Chen, Jui-Fang Liu, Jui-Fang Liu, Hui-Ling Lin, Hui-Ling Lin, Hui-Ling Lin

“…The IMT group had significantly shorter ventilator days (12.6 ± 5.2 vs. 18.1 ± 8.8, p = 0.04). …”
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The expression of exosomal and cellular miRNAs in predicting oxaliplatin resistance in colorectal cancer cells: an in silico and in vitro study by Hoda Deli, Zeynab Vakili-Ghartavol, Yazdan Asgari, Gholamreza Tavoosidana, Ebrahim Eftekhar, Mohammad Hossein Ghahremani

“…Therefore, it is crucial to comprehend the molecular mechanisms of oxaliplatin resistance and develop effective strategies to counter drug resistance. Numerous studies have demonstrated the close association between microRNAs (miRNAs) and drug resistance in CRC. …”
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Safety and Effectiveness of BPaL-Based Regimens to Treat Multidrug-Resistant TB: First Experience of an Italian Tuberculosis Referral Hospital by Gina Gualano, Maria Musso, Paola Mencarini, Silvia Mosti, Carlotta Cerva, Pietro Vittozzi, Antonio Mazzarelli, Angela Cannas, Assunta Navarra, Stefania Ianniello, Paolo Faccendini, Fabrizio Palmieri

“…<b>Conclusions</b>: BPaL-containing regimens also serve as promising options for patients with RR/MDR-TB in terms of real-life experience, but further multicentric studies are required in Europe to confirm the efficacy of shorter regimens to eliminate MDR TB.…”
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Delta large-channel endoscopy versus unilateral biportal endoscopy decompressive laminectomy for lumbar spinal stenosis: a prospective randomized controlled trial by Rushuo Wei, Weiqiang Liu, Mingdong Yu, Yushan Zhu, Ruzhan Yao, Bingwu Wang, Jesse Li-Ling

“…Operation times were shorter in the Delta group (P < 0.001). Hospitalization costs and intraoperative blood loss were slightly higher in the UBE group (P < 0.001). …”
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Transforaminal Endoscopic Lumbar Discectomy versus Coblation Nucleoplasty Combined with Collagenase Chemonucleolysis for Lumbar Disc Herniation with Grade I Degenerative Spondyloli... by Yuyu Guo, Liuhu Han, Tingting Li, Bingbing Xu, Penghui Ke, Jun Hu, Rongyi Zhang, Yan Guo, Long Zhao, Likui Wang

“…Compared with CN combined with CCNL, TELD had more significant improvement in early lower back and leg pain and shorter post-operative duration of hospitalization. …”
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Efficacy of medical thoracoscopy combined with fibrinolytic therapy in the treatment of complicated parapneumonic effusions and empyema by Feng-Fu Zhan, Mao-Hong Huang, Yan-Ping Du, Yan Chen, Han-Han Chen, Yi-Li Lin, Yi-Yuan Chen, Ling Cai, Xiao-Bin Zhang

“…Compared to the traditional treatment group, the thoracoscopy group exhibited significantly lower postoperative inflammatory marker levels (P < 0.05), alongside shorter durations of postoperative fever, pleural drainage, intravenous antibiotic use, and hospital stay (all P < 0.05). …”
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Management Outcomes of Variceal Bleeding in Northern Tanzania: Insights From a Single‐Center Retrospective Analysis by Eliada B. Nziku, Elifuraha W. Mkwizu, Abid M. Sadiq, Fuad H. Said, Doreen T. Eliah, Ibrahim Ali Ibrahim Muhina, Tumaini E. Mirai, Furaha S. Lyamuya, Nyasatu G. Chamba, Elichilia R. Shao, Kajiru G. Kilonzo, Sarah J. Urasa

“…In‐hospital mortality was 8.1%, and factors associated with mortality were a shorter length of stay (p = 0.045), patients without comorbidities (p = 0.041), and grade II esophageal varices (p = 0.043). …”
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