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The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches
Published 2024-12-01“…This narrative review underscores the need for continued research into the molecular mechanisms underlying these interactions and suggests future directions for therapeutic development, including clinical trials, biomarker discovery, and combination therapies that synergistically target aging processes.…”
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42
The aging hematopoietic stem cell niche: a mini review
Published 2025-02-01“…We will highlight current controversies, research gaps, and future directions.…”
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Stem Cell Interaction with Somatic Niche May Hold the Key to Fertility Restoration in Cancer Patients
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44
CATALYSTS AND INHIBITORS OF POLITICAL CAREER IN RUSSIA
Published 2020-02-01“…The analysis of the career background of “young” politicians, the main political career elevators, its catalysts and inhibitors, and the speed of professional formation has been reflected in our research. The research was carried out on the base of biographies of 370 civil servants who, as of March 1, 2019, held the posts of deputy ministers or deputy heads of federal departments. …”
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Gaps Manifesting in African Social Work: Eclectic Contexts in Africa
Published 2024-12-01“…The paper used a review of the literature methodology that drew variegated literature from different research engines such as Google Scholar, EBSCOhost, Research Gate, and a few books and book chapters. …”
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46
Traditional food for a sustainable future? exploring vulnerabilities and strengths in Italy’s foodscape and short agrifood chains
Published 2023-08-01“…The analysis is part of the “NODES- Nord Ovest Digitale e Sostenibile” project funded by the Italian Ministry of University and Research.…”
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Exosomal miR-141-3p from PDLSCs Alleviates High Glucose-Induced Senescence of PDLSCs by Activating the KEAP1-NRF2 Signaling Pathway
Published 2023-01-01“…We discovered that PDLSCs underwent premature senescence due to high glucose culture, but they were rejuvenated by PDLSC-Exos. The rejuvenating effects of PDLSC-Exos were notably reversed by cotreatment with ML385, an inhibitor of nuclear factor erythroid 2-related factor 2 (NRF2), indicating that this recovery depended on NRF2 activation. …”
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Advancements in lung regeneration: from bench to bedside
Published 2025-02-01“…From stem cell and cell-based therapies to the utilization of biological and synthetic materials, as well as the strategic deployment of growth factors, a diverse array of strategies is being explored to rejuvenate lung function. By critical analysis of in vitro, preclinical, and clinical studies, this review aims to provide a comprehensive overview of the emerging technology of lung regeneration research, shedding light on promising avenues for future therapeutic interventions.…”
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Synergy Between Smallholder Palm Oil Replanting Policies and Green Energy Initiatives: A Study of Impacts and Policies in Indonesia
Published 2025-01-01“…PSR projects, focused on rejuvenating aging oil palm plantations and adopting environmentally friendly technologies, support more efficient bioenergy production. …”
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University Environment in Student Assessments: Case of the Russian University of Transport
Published 2023-07-01“…Therefore, the attitude of students to their university environment is an actual research topic. The Russian University of Transport (RUT (MIIT)) conducted the online survey of students, during which they were asked an open question regarding university problems and university development. …”
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51
Pluripotency of Dental Pulp Cells and Periodontal Ligament Cells Was Enhanced through Cell-Cell Communication via STAT3/Oct-4/Sox2 Signaling
Published 2021-01-01“…Alternation in culture environment due to cell-cell communications can rejuvenate the biological activity of aged/differentiated cells and stimulate the expression of pluripotency markers. …”
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Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade
Published 2025-02-01“…These modified EVs were then utilized to rejuvenate exhausted CD8+ T cells blocking PD-L1, resulting in significant therapeutic benefits for GBM treatment. …”
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Effectiveness of Retail Promotions in the Green Industry by Age Group: A Case Study
Published 2020-03-01“…The local and ‘grow your own food’ movements are likely the main drivers of increased interest in edible and food producing plants (National Gardening Association, 2013). To date, research addressing retail promotions in the green industry by age segments has not been adequately addressed. …”
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Effectiveness of Retail Promotions in the Green Industry by Age Group: A Case Study
Published 2020-03-01“…The local and ‘grow your own food’ movements are likely the main drivers of increased interest in edible and food producing plants (National Gardening Association, 2013). To date, research addressing retail promotions in the green industry by age segments has not been adequately addressed. …”
Get full text
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