HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in... by Augustine T Choko, Elizabeth L Corbett, Nigel Stallard, Hendramoorthy Maheswaran, Aurelia Lepine, Cheryl C Johnson, Doreen Sakala, Thokozani Kalua, Moses Kumwenda, Richard Hayes, Katherine Fielding

“…Women attending an ANC for the first time for their current pregnancy (regardless of trimester), 18 years and older, with a primary male partner not known to be on ART were enrolled in the trial after giving consent. Randomisation was to either the standard of care (SOC; with a clinic invitation letter to the male partner) or 1 of 5 intervention arms: the first arm provided women with 2 HIVST kits for their partners; the second and third arms provided 2 HIVST kits along with a conditional fixed financial incentive of $3 or $10; the fourth arm provided 2 HIVST kits and a 10% chance of receiving $30 in a lottery; and the fifth arm provided 2 HIVST kits and a phone call reminder for the women's partners. …”
Get full text

Study of hereditary non-syndromic ophthalmic pathology of child population of the Karachay-Cherkess Republic: features and structure of nosological spectrum by V.V. Kadyshev, A.V. Marakhonov, S.I. Kutsev, R.A. Zinchenko

“…<br> <b>Patients and Methods:</b> 90793 children from 10 regions of the Karachay-Cherkess Republic between the ages of 0 and 18 were examined, of which 121 people were enrolled in set. To solve the problem, genetic and epidemiological, clinical, paraclinical examination methods were used.…”
Get full text

Analyzing the efficacy of a novel method for detecting achromatopsia by N.V. Sukhanova, S.I. Rychkova, V.G. Likhvantseva, R.I. Sandimirov, V.V. Kadyshev, R.A. Zinchenko

“…</p> <p> <b>Patients and Methods:</b> twenty patients with congenital achromatopsia established by genetic testing were enrolled. Sixteen (80%) patients were diagnosed with mutations in the CNGB3 gene and 4 (20%) patients were diagnosed with mutations in the CNGA3 gene. …”
Get full text

CHARACTERISTICS OF CIRCADIAN BLOOD PRESSURE PROFILE IN PATIENTS WITH ACUTE CORONARY SYNDROME AND THEIR ASSOCIATION WITH THYROID FUNCTION by Nataliia Kuz, Tetiana Solomenchuk

“…To study thyroid function in patients enrolled, TSH and FT4 levels were determined by chemiluminescent immunoassay method on the ARCHITECT iSystem analyzer using reagent kits for the quantitative determination of TSH (ARCHITECT TSH) and FT4 (ARCHITECT Free T4). …”
Get full text

Direct maternal morbidity and the risk of pregnancy-related deaths, stillbirths, and neonatal deaths in South Asia and sub-Saharan Africa: A population-based prospective cohort stu... by Fahad Aftab, Imran Ahmed, Salahuddin Ahmed, Said Mohammed Ali, Seeba Amenga-Etego, Shabina Ariff, Rajiv Bahl, Abdullah H Baqui, Nazma Begum, Zulfiqar A Bhutta, Godfrey Biemba, Simon Cousens, Vinita Das, Saikat Deb, Usha Dhingra, Arup Dutta, Karen Edmond, Fabian Esamai, Amit Kumar Ghosh, Peter Gisore, Caroline Grogan, Davidson H Hamer, Julie Herlihy, Lisa Hurt, Muhammad Ilyas, Fyezah Jehan, Mohammed Hamad Juma, Michel Kalonji, Rasheda Khanam, Betty R Kirkwood, Aarti Kumar, Alok Kumar, Vishwajeet Kumar, Alexander Manu, Irene Marete, Usma Mehmood, Nicole Minckas, Shambhavi Mishra, Dipak K Mitra, Mamun Ibne Moin, Karim Muhammad, Sam Newton, Serge Ngaima, Andre Nguwo, Muhammad Imran Nisar, John Otomba, Mohammad Abdul Quaiyum, Sophie Sarrassat, Sunil Sazawal, Katherine E Semrau, Caitlin Shannon, Vinay Pratap Singh, Sajid Soofi, Seyi Soremekun, Atifa Mohammed Suleiman, Venantius Sunday, Thandassery R Dilip, Antoinette Tshefu, Yaqub Wasan, Kojo Yeboah-Antwi, Sachiyo Yoshida, Anita K Zaidi, Alliance for Maternal and Newborn Health Improvement (AMANHI) maternal morbidity study group

“…We measured blood pressure and proteinuria to define hypertensive disorders of pregnancy and woman's self-report to identify obstetric haemorrhage, pregnancy-related infection, and prolonged or obstructed labour. Enrolled women whose pregnancy lasted at least 28 weeks or those who died during pregnancy were included in the analysis. …”
Get full text

Construction of a prognostic model for gastric cancer based on immune infiltration and microenvironment, and exploration of MEF2C gene function by Si-yu Wang, Yu-xin Wang, Lu-shun Guan, Ao Shen, Run-jie Huang, Shu-qiang Yuan, Yu-long Xiao, Li-shuai Wang, Dan Lei, Yin Zhao, Chuan Lin, Chang-ping Wang, Zhi-ping Yuan

“…Finally, 10 patients with advanced GC were enrolled from Sun Yat-sen University Cancer Center, including paired tumor tissues, paracancerous tissues and peritoneal metastases, for preparing sequencing library, in order to perform external validation. …”
Get full text

The prognosis and metabolite changes of NSCLC patients receiving first‐line immunotherapy combined chemotherapy in different M1c categories according to 9th edition of TNM classifi... by Liang Zheng, Fang Hu, Wei Nie, Jun Lu, Bo Zhang, Jianlin Xu, Shuyuan Wang, Ying Li, Xiaoxuan Zheng, Wei Zhang, Yinchen Shen, Runbo Zhong, Tianqing Chu, Baohui Han, Hua Zhong, Xueyan Zhang

“…Method In this study, 33 NSCLC patients lacking driver gene mutations diagnosed with M1c1, and 22 similarly diagnosed with M1c2 according to the 9th edition of TNM Classification, were enrolled. These patients received first‐line PD‐1 inhibitor plus chemotherapy. …”
Get full text

Clinical and experimental rationale for using phenylephrine with hypromellose for the treatment of extra accommodation strain in patients with myopia by M.V. Makhova, E.V. Shikh, V.V. Strakhov, D.S. Blinov, G.K. Poluosmak, E.V. Semeleva, E.V. Blinova

“…</p> <p> <b>Patients and Methods:</b> this clinical study enrolled 122 schoolchildren, 11–17 years old, with extra accommodation strain of various severity. …”
Get full text

Pegilated interferon alpha 2b «Pegaltevir» chronic hepatitis C treatment (randomized clinical trial) by Marina V. Mayevskaya, Ye. N. Bessonova, P. O. Bogomolov, N. I. Geyvandova, K. V. Zhdanov, V. G. Morozov, V. D. Pasechnikov, I. Yu. Khomenko, A. V. Yagoda, V. T. Ivashkin

“…Assessment of Pegaltevir® efficacy was carried out in 4 weeks (rapid virologic response, RVR) and 12 weeks of treatment (early virologic response, EVR) in groups 1 and 3 in comparison to corresponding scores in groups 2 and 4 (primary criteria of efficacy were estimated in all 140 patients enrolled in original study. The response rate at the moment of secession of antiviral therapy, the sustained virologic response (SVR), histologic response (comparison of paired liver biopsies) served as secondary efficacy criteria and were estimated in 129 patients who completed treatment. …”
Get full text

Editorial by Ann-Kristin Kölln, Antony Mason, Jörg Tremmel, Markus Rutsche, Maria Lenk

“…Drawing on social network and political participation theory and novel survey data from Belgium, Paulis explores what network patterns contribute to young people’s enrolment in a political party. He discovers strong social ties between young party members and suggests that this indicates “a certain exclusivity in recruitment patterns of political parties”. …”
Get full text

The efficacy and safety of Ginkgo biloba L. leaves extract combined with ACEI/ARB on diabetic kidney disease: a systematic review and meta-analysis of 41 randomized controlled tria... by Zehua Zhang, Shiyun Tang, Shiyu Liu, Yulin Leng, Xiaoxu Fu, Hongyan Xie, Hong Gao, Hong Gao, Chunguang Xie, Chunguang Xie

“…The publication bias was evaluated with the funnel plot and Egger’s test, and the evidence quality was evaluated by the Grading of Recommendations Assessment, Development and Evaluation (GRADE) method.ResultsA total of 41 studies with 3,269 patients were finally enrolled in this study. None of the included studies reported whether renal or cardiovascular disease progression events occurred. …”
Get full text

Application of cellular microstructural diffusion MRI (cell size imaging) in rectal lesions: a preliminary study by Peisi Kou, Liangjie Lin, Ying Li, Hui Qin, Kun Zhang, Wenhua Zhang, Juan Li, Yong Zhang, Jingliang Cheng

“…ObjectivesTo explore the value of cellular microstructural mapping by IMPULSED (imaging microstructural parameters using limited spectrally edited diffusion) method in evaluating the histological type and prognostic factors of rectal lesions.Materials and methodsSixty-six patients with rectal lesions were enrolled in this study. All subjects underwent MRI scans including conventional diffusion weighted imaging (DWI) and the IMPULSED MRI scans of oscillating gradient spin-echo (OGSE) and pulse gradient spin-echo (PGSE) sequences. …”
Get full text

An alternative to the straddle-arm technique for a conscious infant who is choking: Towards a more universal skill by Ada Chan, Adam Gesicki

“…Results &amp; Conclusion Of the 40 initially enrolled, 37 participants completed the study protocol. …”
Get full text

A survey of knowledge about health education and self-management behavior in 118 patients with early diabetic nephropathy (118例早期糖尿病肾病患者健康教育知识水平及自我管理行为现状调查)... by CHEN Furong (陈芙蓉), ZHOU Jianping (周建平), MAO Dandan (毛丹旦), BO Jing (薄静), ZHUANG Ji (庄姬)

“…Methods A convenience sample of 118 patients with early diabetic nephropathy was enrolled. The general information, patients’ knowledge about health education and their self-management behavior were assessed by self-made Knowledge Assessment Scale and the Summary of Diabetes Self-Care Activities Measure(SDSCA). …”
Get full text

Effect of Chinese herbal medicine pack hot compress on relieving the pruritus in diabetes patients with deficiency of both Qi and Yin syndrome (药包热敷器治疗气阴两虚型糖尿病皮肤瘙痒效果观察)... by YUAN Zheng (袁铮), LIU Qing (刘青), CHEN Yuanyuan (陈媛媛), LI wei (李伟)

“…Using Traditional Chinese Medicine syndrome integral scale, Visual Analogue Scale(VAS) and Pittsburgh Sleep Quality Index (PSQI) to measure the degree of pruritus symptoms and sleep quality before enrollment and 14 days after treatment. Results The pruritus response rate in the intervention group was 96. 88% (31/32) and 75%(24/32) in the control group, with as significant difference (P＜0. 05). …”
Get full text

The study of interactome in Russian patients with Usher syndrome to select priority approaches in pathogenetically oriented treatment by M.E. Ivanova, D.S. Atarshchikov, A.M. Demchinsky, V.V. Strelnikov, D. Barh, G.V. Poryadin, L.M. Balashova, J.M. Salmasi

“…</i> </p> <p> <i><b>Patients and Methods: </b>28 patients with USH were enrolled in the study and underwent examinations (clinical trial protocol No. …”
Get full text

Clonal hematopoiesis of indeterminate potential and type 2 diabetes mellitus among patients with STEMI: from a prospective cohort study combing bidirectional Mendelian randomizatio... by Xiaoxiao Zhao, Jiannan Li, Shaodi Yan, Yu Tan, Runzhen Chen, Nan Li, Jinying Zhou, Chen Liu, Peng Zhou, Yi Chen, Hongbing Yan, Hanjun Zhao, Li Song

“…(iv) The correlation between PCSK9 and the Tet2-CHIP mutation was observed in both the T2DM cohort (correlation = 0.1215, P = 0.011) and the overall enrolled cohort (correlation = 0.0578, P = 0.0382). …”
Get full text

Training Psychological Skills: Efficacy and Assessment of a Nonclinical Psychological Sports Coaching E-Intervention for Young Elite Athletes by Raphaël Bonetti, Fabienne Crettaz von Rotten, Denis Hauw

“…Participants aged 13 to 18 (M = 14.67, SD = 1.13) trained an average of 4.10 times per week (SD = 1.01) and had been practicing their sport for an average of 8.65 years (SD = 2.46). All athletes were enrolled in training centers recognized by their regional committees and were potential candidates for national youth teams. …”
Get full text

“CPR Posture” for Hemorrhage Control

“…Results: Thirty participants were enrolled and had data available for analysis. Demographics were statistically similar across groups. …”
Get full text

Level-8 Ph.D. Programs In Medical Sciences: High Time For The Higher Education Commission (HEC) Of Pakistan To Establish A Medical Wing by Wafa Omer

“…These degrees are full-time on-campus programs and face-to-face learning during the course is essential. The PhD trainees enrolled across all fields of Pathology are deputed in the diagnostic medical laboratories of the affiliated hospitals and are involved in clinical diagnostic work along with research. …”
Get full text